Prolongation of rat islet allograft survival by direct ultraviolet irradiation of the graft.
Science
; 223(4636): 607-9, 1984 Feb 10.
Article
em En
| MEDLINE
| ID: mdl-6420888
ABSTRACT
Ultraviolet irradiation of rat dendritic cells completely abrogated their allostimulatory capacity in a mixed lymphocyte reaction. Rat islets of Langerhans similarly irradiated remained hormonally functional when transplanted into syngeneic diabetic rats. Allogeneic transplantation across a major histocompatibility barrier of islets initially treated in vitro with ultraviolet irradiation resulted in prolonged allograft survival without the use of any immunosuppressive agents.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Raios Ultravioleta
/
Transplante das Ilhotas Pancreáticas
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1984
Tipo de documento:
Article