Anatomical site-specific modalities for hyperthermia.
Cancer Res
; 44(10 Suppl): 4842s-4852s, 1984 Oct.
Article
em En
| MEDLINE
| ID: mdl-6467237
ABSTRACT
The clinical application of hyperthermia in the treatment of deep-seated tumors remains an empirical science. The pleomorphic nature of the neoplasms and the great diversity in the anatomy and physiology of the individual tumor locations make the treatment of nearly every neoplasm a unique challenge. A wide variety of devices is required, both for the administration of hyperthermia and for the measurement of the temperatures achieved. At Stanford University, these include the BSD Medical Corp. annular phased array system, an isospherical ultrasound device, and interstitial radiofrequency for deep heating. Ultrasound transducers and a variety of microwave applicators are used for superficial hyperthermia. Six illustrative case studies, selected from the 91 patients treated in our program since October 1981, are presented, with discussion and comparison of treatment devices. Difficulties in deep heating were encountered in several instances, believed secondary to the thickness of the s.c. fat, the relatively high heat-induced tumor blood flow, and the presence of adjacent bone. It is suggested that ultimate improvement in clinical results will be possible once a better understanding is achieved of such anatomical and physiological factors.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia por Ultrassom
/
Carcinoma de Células Escamosas
/
Adenocarcinoma
/
Neoplasias do Colo
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Neoplasias de Cabeça e Pescoço
/
Hipertermia Induzida
/
Micro-Ondas
/
Neoplasias
Limite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Cancer Res
Ano de publicação:
1984
Tipo de documento:
Article