Stem cell carcinoma in the small intestine of mice treated transplacentally with N-ethyl-N-nitrosourea: some quantitative and histological aspects.
Cancer Lett
; 25(1): 71-9, 1984 Nov.
Article
em En
| MEDLINE
| ID: mdl-6518453
ABSTRACT
A high incidence of tumours of the small intestine occurred in mice of the B10.A/SgSnA strain treated transplacentally with N-ethyl-N-nitrosourea (ENU). In these adenocarcinomas, histologically different tumour cells which resembled the 4 cell types of the normal intestinal epithelium were present. Since normal intestinal epithelial cells are thought to originate from common stem cells, the tumours seem to be derived from these stem cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Células-Tronco Neoplásicas
/
Adenocarcinoma
/
Neoplasias Intestinais
/
Intestino Delgado
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Cancer Lett
Ano de publicação:
1984
Tipo de documento:
Article