Antireproductive effects of a potent gonadotropin-releasing hormone antagonist in the male rat.
Science
; 210(4465): 93-5, 1980 Oct 03.
Article
em En
| MEDLINE
| ID: mdl-6774418
ABSTRACT
Administration of a potent antagonist of gondadotropin-releasing hormone (GnRH) antagonist [Ac-dehydro-Pro1, pCl-D-Phe2, D-Trp3,6]-N alpha-MeLeu7-GnRH to adult male rats for 2 weeks resulted in decreased testosterone production and sexual organ weights and in disrupted spermatogenesis. The results demonstrate the essential role of gonadotropin-releasing hormone in the maintenance of reproductive functions and have implications for the regulation of male fertility.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hormônios Inibidores da Liberação de Hormônio Hipofisário
/
Hormônios Liberadores de Hormônios Hipofisários
/
Hormônio Liberador de Gonadotropina
/
Infertilidade Masculina
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1980
Tipo de documento:
Article