Platelet-bound IgG in systemic lupus erythematosus with and without thrombocytopenia.
J Immunol Methods
; 45(3): 275-81, 1981.
Article
em En
| MEDLINE
| ID: mdl-7288196
ABSTRACT
A new assay for IgG bound to autologous platelets is described, in which IgG is dissociated from platelets washed at low pH, then measured by radioimmunoassay. Platelet-bound IgG was found to be elevated in thrombocytopenic patients with SLE and reduced in non-thrombocytopenic patients with this disease. There was a close inverse correlation of platelet-bound IgG and platelet count. Immune complexes did not interfere with the assay.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sítios de Ligação de Anticorpos
/
Plaquetas
/
Imunoglobulina G
/
Lúpus Eritematoso Sistêmico
Limite:
Humans
Idioma:
En
Revista:
J Immunol Methods
Ano de publicação:
1981
Tipo de documento:
Article