Experimental inflammatory serous detachment of the retina.
Arch Ophthalmol
; 98(12): 2217-9, 1980 Dec.
Article
em En
| MEDLINE
| ID: mdl-7447779
ABSTRACT
Rhesus monkey eyes were studied after the development of inflammatory serous retinal detachments following internal carotid artery injection of live, yeast-phase Histoplasma capsulatum organisms. Horseradish peroxidase (HRP) was used as a tracer to examine the inner and outer blood-retinal barriers. The HRP was present in a decreasing gradient from the choroid into the subretinal space and was not found to have leaked from retinal vessels. The source of subretinal fluid in this model of inflammatory serous retinal detachment was leakage from the choroid through a defective outer blood-retinal barrier, induced by disruption of the retinal pigment epithelium. This model has relevance to understanding the serous retinal detachments common to diseases affecting the choroid.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Epitélio Pigmentado Ocular
/
Descolamento Retiniano
/
Corioidite
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Arch Ophthalmol
Ano de publicação:
1980
Tipo de documento:
Article