[Interactions between chronic viral hepatitis C and pregnancy]. / Interactions entre l'hépatite virale chronique C et la grossesse.
Gastroenterol Clin Biol
; 19(5): 520-4, 1995 May.
Article
em Fr
| MEDLINE
| ID: mdl-7590005
ABSTRACT
OBJECTIVES AND METHODS:
In France, the positive rate for unit-HCV antibodies in the sera of pregnant women is usually found to be between 0.7 and 3.9%. The aim of our prospective study was to determine the interactions between pregnancy and chronic viral hepatitis C in 12 pregnant women.RESULTS:
In our study, chronic viral hepatitis C did not influence maternal or neonatal outcome. The mean gestational age was 38.4 +/- 3 weeks. During follow-up, mean serum ALT levels were significantly lower (36 +/- 17 mU/mL) during the last three months of pregnancy compared to before pregnancy (237 +/- 144 mU/mL, P < 0.002) and after pregnancy (141 +/- 62 mU/mL, P < 0.0005). During the third trimester, serum ALT levels were normal in 90% of the women. However, the persistence of viremia during pregnancy and a rebound in serum ALT during the post-partum period have been noticed.CONCLUSION:
The normalization of serum ALT levels during pregnancy, the persistence of viremia, and a rebound in serum ALT during post-partum could be related to pregnancy-induced changes in the immune system.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
RNA Viral
/
Anticorpos Anti-Hepatite
/
Hepatite C
/
Alanina Transaminase
/
Hepatite Crônica
Tipo de estudo:
Observational_studies
/
Prevalence_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
País/Região como assunto:
Europa
Idioma:
Fr
Revista:
Gastroenterol Clin Biol
Ano de publicação:
1995
Tipo de documento:
Article