Repeated treatment with fluoxetine decreases the number of spontaneously active cells per track in frontal cortex.
Eur J Pharmacol
; 271(1): 231-4, 1994 Dec 12.
Article
em En
| MEDLINE
| ID: mdl-7698206
ABSTRACT
Repeated (10 mg/kg i.p. x 14 days, once daily), but not acute (10 and 40 mg/kg i.p., 30 min), treatment with fluoxetine decreased the number of active neurons in the frontal cortex 30 min (-55%) or 24 h (-62%) after the last drug injection. This result supports the view that repeated, but not acute, treatment with fluoxetine decreases the function of the frontal cortex.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fluoxetina
/
Lobo Frontal
Limite:
Animals
Idioma:
En
Revista:
Eur J Pharmacol
Ano de publicação:
1994
Tipo de documento:
Article