[The characteristics of pneumococcal contamination of the respiratory tract in healthy and sick children]. / Osoblyvosti kontaminatsiï pnevmokokom verkhnikh dykhal'nykh shliakhiv zdorovykh ta khvorykh ditei.

ABSTRACT

The results of six-year-long investigations of microbiological indices of pneumococcal microflora in healthy carriers and in children with chronic respiratory pathology are presented in the paper. Peculiarities of pneumococcal contamination of nasopharynx mucosa in the both groups were detected. A difference in the intensity of pneumococcus colonization and localization in upper respiratory tract between healthy and sick children was found. Data on adhesive and lysozyme activity of the obtained stocks as factors favourable for microflora contamination and persistence on nasopharynx mucosa are given. An analysis of antibiograms of the obtained pneumococcus cultures was performed. The recent trend of preservation of pneumococcus sensitivity to the main groups of commonly used antibiotic preparations has been affirmed.