Utilization of dietary nucleic acid purines for nucleotide and nucleic acid synthesis in the mouse.
Can J Biochem
; 54(5): 500-6, 1976 May.
Article
em En
| MEDLINE
| ID: mdl-776369
ABSTRACT
Three preparations of radioactive yeast nucleic acids were fed to mice. One was labeled predominantly in the guanine moiety, one was labeled predominantly in the adenine moiety, and in one adenine and guanine were labeled equally. Most of the nucleic acid purines produced by digestion were excreted in the urine. However, a small amount was utilized for nucleotide and nucleic acid synthesis in the mouse tissues. Small intestine, liver and skeletal muscle contained most of the purines that were retained in the tissues. Dietary nucleic acid adenine appeared to be utilized somewhat more efficiently than was dietary nucleic acid guanine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Purinas
/
DNA
/
RNA
Limite:
Animals
Idioma:
En
Revista:
Can J Biochem
Ano de publicação:
1976
Tipo de documento:
Article