Resistance of E. coli strains, recovered from chickens to antibiotics with particular reference to trimethoprim-sulfamethoxazole (septrin).
East Afr Med J
; 71(10): 624-7, 1994 Oct.
Article
em En
| MEDLINE
| ID: mdl-7821238
ABSTRACT
Thirty-seven strains of E. coli recovered from cases of septicaemia in chicken were tested for sensitivity to 6 antibiotics. Minimum inhibitory concentration (MIC) determinations done on the strains showed resistance to trimethoprim-sulfamethoxazole (septrin) (100%), ampicillin (62.2%), tetracycline (51.4%), kanamycin (13.5%) and gentamicin (2.7%). All were sensitive to chloramphenicol. Conjugation studies showed easy transfer of the resistance factor for septrin to the recipient sensitive strain, K12F-, a 60 megadalton plasmid was transferred in most of the cases (a number of plasmids moved across to K12F- strains). Septrin was chosen as a referral antibiotic because it is used extensively for treating diarrhoeal cases in children in Kenya. The results expressed the possibility of the chicken being the possible source of the septrin resistance gene (plasmid) for humans, and vice versa.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças das Aves Domésticas
/
Resistência a Trimetoprima
/
Combinação Trimetoprima e Sulfametoxazol
/
Galinhas
/
Sepse
/
Escherichia coli
/
Infecções por Escherichia coli
Limite:
Animals
/
Child
/
Humans
País/Região como assunto:
Africa
Idioma:
En
Revista:
East Afr Med J
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Quênia