Pharyngeal carriage of Neisseria meningitidis before and after treatment of meningococcal disease.
J Med Microbiol
; 41(5): 339-42, 1994 Nov.
Article
em En
| MEDLINE
| ID: mdl-7966206
ABSTRACT
The aim of the study was to determine whether patients with meningococcal disease carry meningococci in the throat both before and after treatment for the disease. During the 7 months of the study 106 patients with confirmed meningococcal disease were admitted to Danish hospitals, of whom 77 (73%) had a throat swab examined at least once and were included in the study. Sixty-two patients were examined on admission and 52 were examined on discharge; 37 were examined on both occasions. On admission, meningococci were isolated from 18 (49%) of 37 throat specimens examined selectively for pathogenic Neisseria spp. Meningococci were not isolated from any throat specimen taken on discharge from hospital; 47 (90%) of 52 of these specimens had been examined adequately. From an observed carriage rate of 0 out of 47 it can be judged that the carrier rate does not exceed 6.4% (95% confidence limit). From these results we conclude that it is unlikely that patients who have been treated for meningococcal disease according to the regimens used in Denmark can be the source of infection for secondary cases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Faringe
/
Portador Sadio
/
Infecções Meningocócicas
/
Neisseria meningitidis
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
J Med Microbiol
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Dinamarca