Risk factors for infection by Pseudomonas aeruginosa in patients with ventilator-associated pneumonia.
Intensive Care Med
; 20(3): 193-8, 1994.
Article
em En
| MEDLINE
| ID: mdl-8014285
ABSTRACT
OBJECTIVE:
to investigate the epidemiology of infection by Pseudomonas aeruginosa in patients with ventilator-associated pneumonia (VAP).DESIGN:
prospective clinical study.SETTING:
a medical-surgical ICU in a university hospital. PATIENTS we followed-up 568 mechanically ventilated patients and 83 episodes of VAP with etiologic diagnosis in 72 patients were retained for analysis.RESULTS:
Ps. aeruginosa was isolated in 22 (26.5%) episodes in 18 patients. Of these episodes 7 were directly responsible for death. Using logistic regression analysis, the risk of VAP due to Ps. aeruginosa was increased in patients with chronic obstructive pulmonary disease (relative risk (RR) = 29.9, 95% confidence interval (CI) = 4.86-184.53), a mechanical ventilation period longer than 8 days (RR = 8.1, 95% CI = 1.01-65.40) and prior use of antibiotics (RR = 5.5, 95% CI = 0.88-35.01).CONCLUSIONS:
patients with VAP and these factors have a greater risk of infection by Ps. aeruginosa and empirical therapy for these episodes should include anti-pseudomonal activity until etiologic diagnosis is established.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia
/
Pseudomonas aeruginosa
/
Infecções por Pseudomonas
/
Respiração Artificial
/
Infecção Hospitalar
/
Controle de Infecções
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Intensive Care Med
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Espanha