Perinatal transmission of HIV-2 infection in malnourished children in Guinea Bissau.
New Microbiol
; 17(1): 61-4, 1994 Jan.
Article
em En
| MEDLINE
| ID: mdl-8127231
ABSTRACT
Since there have been a few reports of pediatric HIV-2 infection. We therefore investigated the perinatal transmission of HIV-2 in 147 malnourished and 164 well-nourished children attending a health center in the northern part of Guinea Bissau. Specific HIV-2 antibodies were detected in 17 mothers and in 2 malnourished children, one of them with pediatric AIDS. This study demonstrates that mother to child transmission of HIV-2 infection occurs in Guinea Bissau and suggests that there is an increased likelihood of detecting HIV-2 infection in malnourished children. The high seroprevalence of HIV-2 in a rural population without known risk factors may represent a hidden threat to mother/child health.
ABSTRACT
PIP The authors tested blood samples of 147 malnourished children, 164 well-nourished children, and their 205 mothers with the goal of exploring the extent to which HIV-1 and HIV-2 were being transmitted perinatally in Guinea-Bissau. The children were attending a health center in the northern part of Guinea-Bissau and had been breast fed from birth to 20 months of age or longer. Analysis found antibodies to HIV-2 in 17 mothers and 2 malnourished children, one with pediatric AIDS. These findings demonstrate the occurrence of mother-to-child transmission of HIV-2 in the country and suggest a possible increased likelihood of detecting HIV-2 infection in malnourished children. The high seroprevalence of HIV-2 infection in a rural population without known risk factors may represent a hidden threat to the health of mothers and children.
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Base de dados:
MEDLINE
Assunto principal:
Transtornos da Nutrição Infantil
/
Infecções por HIV
/
Síndrome da Imunodeficiência Adquirida
/
HIV-2
Tipo de estudo:
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
New Microbiol
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
1994
Tipo de documento:
Article