Lidocaine as a diluent for ceftriaxone in the treatment of gonorrhea. Does it reduce the pain of the injection?
Arch Pediatr Adolesc Med
; 148(1): 72-5, 1994 Jan.
Article
em En
| MEDLINE
| ID: mdl-8143016
ABSTRACT
OBJECTIVE:
To compare the pain associated with ceftriaxone sodium injections by using two different diluents, ie, lidocaine hydrochloride and sterile water.DESIGN:
Prospective study of adolescents who were culture positive for gonorrhea. Random selection of the diluent used for the intramuscular ceftriaxone therapy.SETTING:
Urban, hospital-based adolescent medicine service.SUBJECTS:
Thirty-nine adolescents and young adults, predominantly of black or Hispanic backgrounds, ranging in age between 14 and 23 years (mean age, 17.6 years; median age, 17 years), of whom 27 were females.METHODS:
Pain predictions were elicited from the adolescents before treatment. Pain ratings were obtained at five time intervals after the injections. All ratings were obtained by using a visual analog scale.RESULTS:
No pain prediction differences before the injection were noted between the two groups. Individual t tests showed significant pain differences between the two groups at the time after the injection and at 10- and 20-minute and 6-hour intervals. Repeated-measures analysis of variance models showed that the diluent effect on pain was significant.CONCLUSION:
Lidocaine can reduce the amount of pain of an intramuscular injection of ceftriaxone when compared with sterile water as a diluent. These findings have implications not only for the treatment of gonorrhea but also for other situations where intramuscular injections utilizing a diluent may be necessary.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dor
/
Ceftriaxona
/
Gonorreia
/
Injeções Intramusculares
/
Lidocaína
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Arch Pediatr Adolesc Med
Assunto da revista:
PEDIATRIA
Ano de publicação:
1994
Tipo de documento:
Article