Improved contrast of enhancing brain lesions on postgadolinium, T1-weighted spin-echo images with use of magnetization transfer.
Radiology
; 190(2): 553-9, 1994 Feb.
Article
em En
| MEDLINE
| ID: mdl-8284415
ABSTRACT
PURPOSE:
To prove that the contrast of enhancing brain lesions on post-gadolinium T1-weighted spin-echo (SE) images can be statistically significantly improved with magnetization-transfer (MT) indirect saturation. MATERIALS ANDMETHODS:
The contrast-to-noise ratios (C/Ns) of 201 enhancing brain lesions in 110 patients were compared on conventional and MT T1-weighted SE images obtained at 1.5 T after injection of 0.05-0.10 mmol/kg gadopentetate dimeglumine or gadodiamide.RESULTS:
The MT T1-weighted SE images showed a 37% reduction in signal intensity of background white matter and thereby provided a 108% improvement in the C/N of enhancing brain lesions over the conventional T1-weighted SE images (P < .001).CONCLUSION:
The C/Ns obtained with single-dose gadolinium and the MT T1-weighted SE technique were twice those obtained with the conventional technique and are at least equivalent to reported values obtained with triple-dose gadolinium and conventional T1-weighted SE images.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Encefalopatias
/
Imageamento por Ressonância Magnética
/
Aumento da Imagem
/
Meios de Contraste
/
Ácido Pentético
/
Meglumina
Limite:
Humans
Idioma:
En
Revista:
Radiology
Ano de publicação:
1994
Tipo de documento:
Article