Chlorambucil-associated pneumonitis.
Chest
; 105(2): 634-6, 1994 Feb.
Article
em En
| MEDLINE
| ID: mdl-8306788
ABSTRACT
A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg). Withdrawal of drug treatment was followed by rapid improvement in the clinical condition. Bronchoalveolar lavage showed a T-lymphocytic alveolitis, whereas blood lymphocytes were predominantly of the B phenotype. The T-lymphocytic alveolitis persisted 6 weeks after drug therapy cessation with a predominant CD8+ phenotype, as observed in some hypersensitivity pneumonitis induced by drugs.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Clorambucila
/
Doenças Pulmonares Intersticiais
/
Alveolite Alérgica Extrínseca
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Chest
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
França