Importance of tumor size and repopulation for radiocurability of skin cancer.
Neoplasma
; 40(1): 51-4, 1993.
Article
em En
| MEDLINE
| ID: mdl-8350948
ABSTRACT
Data on 946 skin cancers treated by radiation were used to estimate the importance of repopulation. Six different treatment regimes were used from a single dose to 74 Gy given in 47 fractions. High local control of the small skin cancers (L 1 cm) was independent of dose fractionation. For large tumors, only 74 Gy in 47 fractions was the optimal treatment. Time factor analysis showed a steep increase in the NTD50 values between day 28 and 65 of treatment. This implies that tumor clonogen repopulation starts around 4 weeks of treatment. The present results showed a three-component dose response curve instead of the two-component curves which were found for head and neck and bladder cancer.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Recidiva Local de Neoplasia
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Neoplasma
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Polônia