Brain natriuretic peptide levels in the umbilical venous plasma are elevated in fetal distress.
Biol Neonate
; 64(1): 18-25, 1993.
Article
em En
| MEDLINE
| ID: mdl-8399796
ABSTRACT
We measured, by a specific radioimmunoassay, brain-natriuretic-peptide-like immunoreactive (BNP-LI) levels in the umbilical venous and arterial plasma of normal and distressed newborns. The indicated BNP-LI level in umbilical arterial plasma of normal newborns (3.5 +/- 0.9 fmol/ml, mean +/- SEM, n = 10) was significantly higher than that in umbilical venous plasma of the same newborns (2.2 +/- 0.5 fmol/ml). In the distressed newborns at term, the indicated BNP-LI level in umbilical venous plasma was 62.2 +/- 25.7 fmol/ml (n = 4), which was 19-fold higher than that of elective cesarean section cases (3.2 +/- 0.3 fmol/ml, n = 6; p < 0.05). The findings demonstrated that BNP was present in the human fetal circulation and that the plasma BNP level was elevated under fetal distress conditions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Veias Umbilicais
/
Fator Natriurético Atrial
/
Sangue Fetal
/
Sofrimento Fetal
/
Proteínas do Tecido Nervoso
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Biol Neonate
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Japão