Membrane permeabilization of Listeria monocytogenes and mitochondria by the bacteriocin mesentericin Y105.
J Bacteriol
; 175(10): 3232-5, 1993 May.
Article
em En
| MEDLINE
| ID: mdl-8491741
ABSTRACT
Mesentericin Y105, a bacteriocin produced by a Leuconostoc mesenteroides strain, dissipates the plasma membrane potential of Listeria monocytogenes and inhibits the transport of leucine and glutamic acid. It also induces an efflux of preaccumulated amino acids from cells. In addition, the bacteriocin uncouples mitochondria by increasing state 4 respiration and decreasing state 3 respiration. The bacteriocin inhibits ATP synthase and adenine nucleotide translocase of the organelle while the affinity of ADP for its carrier is not modified. The results suggest that mesentericin Y105 acts by inducing, directly or indirectly, pore formation in the energy-transducing membranes, especially those of its natural target.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bacteriocinas
/
Mitocôndrias Hepáticas
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Permeabilidade da Membrana Celular
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Membranas Intracelulares
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Listeria monocytogenes
Limite:
Animals
Idioma:
En
Revista:
J Bacteriol
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
França