Human papillomavirus deoxyribonucleic acid and ribonucleic acid in seminal plasma and sperm cells.
Fertil Steril
; 65(5): 1026-30, 1996 May.
Article
em En
| MEDLINE
| ID: mdl-8612829
ABSTRACT
OBJECTIVE:
To investigate the possible presence and expression of human papillomavirus viruses (HPV) in human plasma and sperm cells.DESIGN:
Controlled clinical study.SETTING:
A major medical center affiliated with a medical college. PATIENTS Twenty-four randomly selected patients who attended Fertility Clinics at the Chang Gung Memorial Hospital.INTERVENTIONS:
Specimens of semen were collected from volunteered patients MAIN OUTCOMEMEASURE:
The presence of HPV types 16 and 18 DNA and RNA sequences were examined by polymerase chain reaction.RESULTS:
Human papillomavirus type 16 E6 and E7 DNA and RNA sequences were found in two and zero seminal plasma specimens, respectively, and in six and two sperm cells specimens, respectively. Deoxyribonucleic acid and RNA sequences of HPV type 18 were found in eight and two seminal specimens and in 11 and 5 sperm cells specimens, respectively.CONCLUSION:
These results seem to suggest that HPV cannot only infect human sperm cells, certain HPV genes are expressed actively in infected sperm cells. The virus-infected sperm cells conceivably can behave as vectors or carriers for the transmission of HPV, to sexual partner during sexual contact, to fetuses through fertilized eggs, or both.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
Sêmen
/
Espermatozoides
/
DNA Viral
/
RNA Viral
Tipo de estudo:
Clinical_trials
Limite:
Humans
/
Male
Idioma:
En
Revista:
Fertil Steril
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
China