Effects of glycemic control on saliva flow rates and protein composition in non-insulin-dependent diabetes mellitus.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
; 83(4): 465-70, 1997 Apr.
Article
em En
| MEDLINE
| ID: mdl-9127379
ABSTRACT
OBJECTIVE:
The objective of this study was to determine whether improvements in the level of diabetic control in a group of subjects with poorly controlled non-insulin-dependent diabetes mellitus influence salivary output and composition. STUDYDESIGN:
Repeated whole unstimulated and stimulated parotid saliva samples were collected from diabetic patients attending an outpatient diabetes education program and a matched nondiabetic control group. Saliva was analyzed for flow rates, parotid protein concentration and composition, and amylase activity. Subjective responses to questions about salivary hypofunction were tested.RESULTS:
There were no significant differences in whole unstimulated and stimulated parotid flow rates or stimulated parotid protein concentration and composition between diabetics and the control group. Amylase activity was higher in diabetics and decreased with improved glycemic control. Subjects reporting taste alterations had higher mean blood glucose levels than subjects with normal taste sensation.CONCLUSIONS:
Poorly controlled non-insulin-dependent diabetes mellitus has no influence on saliva output, although amylase activity may be elevated, and there may be taste alterations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Saliva
/
Proteínas e Peptídeos Salivares
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Estados Unidos