Study of the delivery of the gD gene of pseudorabies virus to one-day-old piglets by adenovirus or plasmid DNA as ways to by-pass the inhibition of immune response by colostral antibodies.
Vet Microbiol
; 55(1-4): 75-80, 1997 Apr.
Article
em En
| MEDLINE
| ID: mdl-9220598
ABSTRACT
In the present study, it was shown that piglets with maternal antibodies, which had been primed with a replication-defective adenovirus that expresses the pseudorabies virus (PRV) glycoprotein gD and boosted with the Bartha vaccine strain at 10 weeks of age are equally protected clinically upon a challenge as piglets without maternal antibodies vaccinated with the same approach or with the Bartha vaccine strain alone. Priming with a plasmid that expresses gD was less efficient.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pseudorraiva
/
Vacinas Virais
/
Proteínas do Envelope Viral
/
Técnicas de Transferência de Genes
/
Colostro
/
Herpesvirus Suídeo 1
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Vet Microbiol
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
França