Impaired Leydig cell reserve and altered serum androgen binding in the aging male.
Fertil Steril
; 27(7): 812-4, 1976 Jul.
Article
em En
| MEDLINE
| ID: mdl-950050
ABSTRACT
The hormonal profile of the aging male reveals an associated decrease in free testosterone and 5 alpha-dihydrotestosterone (DHT) levels and increased luteinizing hormone levels. Later events consist of a decrease in total testosterone, stable DHT, and increased follicle-stimulating hormone and estradiol levels. Although most available information supports the concept of impaired Leydig cell reserve, our study suggests some degree of hypothalamic-pituitary dysfunction. The signal for increased androgen binding with age is not clear. There is a great deal of individual variation in the time of onset of these events.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ligação Proteica
/
Di-Hidrotestosterona
/
Testosterona
/
Envelhecimento
/
Hormônio Luteinizante
/
Células Intersticiais do Testículo
Limite:
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Fertil Steril
Ano de publicação:
1976
Tipo de documento:
Article