The impact of Alzheimer disease genetics on expert and advanced gerontological nursing practice.
AACN Clin Issues
; 9(4): 513-23, 1998 Nov.
Article
em En
| MEDLINE
| ID: mdl-9855861
ABSTRACT
Alzheimer disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in the United States, affecting as many as 4 million people. Extensive research is under way to identify environmental and genetic risk factors for this complex disease. Currently, four genes are associated with an increased risk for AD the amyloid precursor protein gene on chromosome 21, the Presenilin I gene on chromosome 14, the Presenilin II gene on chromosome 1, and the apolipoprotein E gene on chromosome 19. Expert and advanced practice gerontological nurses are faced with new challenges as a result of these gene discoveries. Gerontological nurses should assess for relevant environmental and genetic risk factors; obtain comprehensive family health histories recorded as pedigrees; integrate genetic information into diagnosis, intervention, and evaluation strategies; initiate and coordinate referrals to genetic specialists; and provide ongoing emotional and decision-making support for patients and families experiencing AD.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testes Genéticos
/
Doença de Alzheimer
/
Enfermagem Geriátrica
/
Enfermeiros Clínicos
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
Idioma:
En
Revista:
AACN Clin Issues
Assunto da revista:
ENFERMAGEM
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Estados Unidos