alpha1-antitrypsin (PI) alleles as markers of Westeuropean influence in the Baltic Sea region.
Hum Hered
; 49(1): 52-5, 1999 Jan.
Article
em En
| MEDLINE
| ID: mdl-9858859
ABSTRACT
The distribution of alpha1-antitrypsin (PI) alleles was studied in an attempt to elucidate migrations and admixture between populations in the Baltic Sea region. The frequency of the PI Z allele, a typically Northwesteuropean marker gene, showed a highly significant regional variation in the Baltic Sea region. The highest frequency (4.5%) was found in the western part of Latvia (Courland). The PI S allele, another marker of Westeuropean influence, also showed an increased frequency in the Courland population. These results indicate that among the populations east of the Baltic Sea the Curonian population has the most pronounced Westeuropean influence. Archaeological data have shown that from the 7th century and for several hundreds of years Courland received immigrations from mainland Sweden and the island of Gotland. We speculate that the increased frequencies of the PI Z alleles and S alleles in Courland may have been caused by these migrations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Marcadores Genéticos
/
Alfa 1-Antitripsina
/
Alelos
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Hum Hered
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Suécia