Biochemical effect of ozone exposure in rats exposed to cigarette smoke.
Arch Environ Health
; 31(6): 290-2, 1976.
Article
em En
| MEDLINE
| ID: mdl-999341
ABSTRACT
Rats were exposed to three cigarettes per day for 35 days, under realistic conditions. Pulmonary glucose-6-phosphate dehydrogenase (G-6-PD) activity in the exposed animals increased 27% over control values (P less than .05). Subsequent exposure to acute, high-dose ozone (3 ppm for 4 hr) decreased the augmented G-6-PD activities to near normal levels, whereas ozone exposures in animals not exposed to cigarette smoke caused mild decreases in pulmonary G-6-PD activities. The importance of these findings with respect to the susceptibility of the smoker to oxidant exposures is unknown.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ozônio
/
Fumar
/
Glucosefosfato Desidrogenase
/
Pulmão
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Arch Environ Health
Ano de publicação:
1976
Tipo de documento:
Article