RESUMEN
The current study focuses on adolescents with sex offense histories and examines sexual reoffending patterns within 2 years of a prior sex offense. We employed inductive statistical models using archival official records maintained by the Florida Department of Juvenile Justice (FDJJ), which provides social, offense, placement, and risk assessment history data for all youth referred for delinquent behavior. The predictive accuracy of the random forest models is tested using receiver operator characteristic (ROC) curves, the area under the curve (AUC), and precision/recall plots. The strongest predictor of sexual recidivism was the number of prior felony and misdemeanor sex offenses. The AUC values range between 0.71 and 0.65, suggesting modest predictive accuracy of the models presented. These results parallel the existing literature on sexual recidivism and highlight the challenges associated with predicting sex offense recidivism. Furthermore, results inform risk assessment literature by testing various factors recorded by an official institution.
Asunto(s)
Delincuencia Juvenil , Modelos Estadísticos , Reincidencia , Delitos Sexuales , Adolescente , Área Bajo la Curva , Niño , Florida , Humanos , Aprendizaje Automático , Curva ROC , Medición de Riesgo/métodosRESUMEN
OBJECTIVE: Early and medium-term improvement of functional capacity and regression of left ventricular hypertrophy was evaluated in the young adult patient group following application of 21 mm or 23 mm bileaflet aortic mechanical valve prosthesis due to aortic stenosis. Methods : Twenty two patients (10 male, 12 female; mean age 27+-8.2 (19-43)) who underwent isolated aortic valve replacement due to rheumatic aortic stenosis, were included in the study. 21 mm and 23 mm bileaflet mechanical prosthesis was used respectively in eight and fourteen patients. The mean body surface area was 1.86 m(2) and 1.68 m(2) respectively in 23 mm and 21 mm prosthesis while 1.73 ±0.25 m(2) for the whole group. Functional capacity was New York Heart Association (NYHA) class II in 9 patients and class III in thirteen patients. Implantation was performed without enlarging the aortic root in all except four patients. In all patients transvalvular gradients, effective orifice area and the diameter of left ventricle were measured with transthoracic echocardiography during rest and after maximal exercise. Mean follow-up was 34±12 months (range 11-57 months). RESULTS: There were no postoperative complications or deaths. All the patients were assessed as NYHA class I with regards to functional capacity (p=0.01). Significant improvements were determined in postoperative mean transvalvular gradient (p=0.005) and left ventricular mass index (p=0.01) when compared with preoperative values. CONCLUSION: Our findings show that replacement with 21 mm and 23 mm mechanical prosthesis provides a significant improvement in regression of symptoms and increase of functional capacity in young adults in early and mid-period without increasing mortality and morbidity.
RESUMEN
This study examines the potential relationship between eating disorders and antisocial behaviors through the lenses of the general theory of crime and general strain theory. We utilized the data from the National Longitudinal Study of Adolescent to Adult Health, a longitudinal study of a nationally representative sample of juveniles in grades 7 to 12 in the United States between 1994 and 2008. We constructed three separate measures of eating disorders and examined their relationships with both petty theft and aggressive behaviors. Results indicated that previous traumatic experiences (such as sexual abuse) are consistent risk factors for eating disorders, and that eating disorders can increase antisocial involvements. Moreover, eating disorders can diminish self-control and agitate depressed moods, which may increase the likelihood of both petty theft and violent conduct, and this effect can extend to later adulthood as well.
Asunto(s)
Trastorno de Personalidad Antisocial/psicología , Trastornos de Alimentación y de la Ingestión de Alimentos/psicología , Problema de Conducta , Distrés Psicológico , Autocontrol , Adolescente , Adulto , Agresión , Crimen , Femenino , Humanos , Delincuencia Juvenil , Estudios Longitudinales , Masculino , Factores de Riesgo , Estados Unidos , Adulto JovenRESUMEN
Venous ulcers that occur due to chronic venous insufficiency are seen on the upper medial malleol of the ankle. Treatment of venous ulcers is protracted and generally the success rate is low. Co-morbid factors play an important role in the success of treatment of venous ulcers. In this case report, we demonstrate successful venous ulcer treatment in a morbidly obese patient with co-morbid conditions.
Asunto(s)
Ablación por Catéter , Obesidad Mórbida/diagnóstico , Vena Safena/cirugía , Úlcera Varicosa/diagnóstico , Insuficiencia Venosa/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Obesidad Mórbida/cirugía , Vena Safena/patología , Resultado del Tratamiento , Ultrasonografía Doppler Dúplex , Úlcera Varicosa/cirugía , Insuficiencia Venosa/cirugíaRESUMEN
BACKGROUND: Surgery of thoracoabdominal aortic aneurysms (TAAA) is associated with high incidence of serious complications. Ischemia/reperfusion (I/R) injury may be responsible for these complications. We investigated the effect of degree of anticoagulation on remote organ I/R injuries and whether heparin is protective against I/R injury in addition to its anticoagulant properties. METHODS: Spraque Dawley rats were used to determine both liver and kidney concentrations of HSP-70,IL-6, MPO in four groups: ischemic control (operation with cross-clamping and intraperitoneal administration of 0.9% saline, n = 7), sham (operation without cross-clamping, n = 7), heparin (ACT level about 200), and high dose heparin (ACT level up to 600). Histological analyses of the organs were performed. RESULTS: Histopathological evaluation of kidney presented significant differences between groups with regards to the cytoplasmic vacuole formation, hemorrhage, tubular cell degeneration and tubular dilatation while heparinized group had best results. The kidney MPO and HSP-70 levels significantly decreased (p < 0.05), but IL-6 level was not significant (p > 0.05) in heparinized group when compared to ischemic control group. No statistically significant intergroup differences were detected in the tissue samples of liver. Immunohistochemical markers of the liver were compared and no statistically significant difference was found among the groups. CONCLUSION: Heparin is an important anticoagulation agent in TAAA surgical procedures but the use of higher levels of heparin in the present study revealed no beneficial effects. Bleeding complications is much less when heparin is used in the real-world clinical practice as ACT levels of 200.
Asunto(s)
Aneurisma de la Aorta Torácica/complicaciones , Heparina/farmacología , Riñón/irrigación sanguínea , Hígado/irrigación sanguínea , Sustancias Protectoras/farmacología , Daño por Reperfusión/tratamiento farmacológico , Animales , Inmunohistoquímica , Riñón/química , Riñón/efectos de los fármacos , Hígado/química , Hígado/efectos de los fármacos , Masculino , Ratas , Ratas Sprague-DawleyRESUMEN
BACKGROUND: We evaluated the vasodilatory effects of two antioxidants, vitamins C (ascorbic acid) and E (α-tocopherol), on radial artery and endothelium-dependent responses in patients awaiting coronary artery bypass surgery. METHODS: The study was performed in three groups. The first group took 2 g of vitamin C orally (n = 31, vitamin C group), the second group took 2 g of vitamin C with 600 mg of vitamin E orally (n = 31, vitamins C + E group), and the third group took no medication (n = 31, control group). After baseline measurements were taken of the radial artery lumen diameter, flow volume and lumen area in the non-dominant radial artery, occlusion was maintained for five minutes with a pressure cuff placed around the arm. The measurements were taken again at the time of deflating the cuff, and 60 seconds later. The measurements were repeated after medication in two of the groups and after placebo in the third group. RESULTS: We compared values of the vitamin C group with those of the vitamins C + E group, and found that the latter were higher than those of the vitamin C group but not statistically significant. In the control group, there was no statistical difference. CONCLUSION: Vitamin C or its combination with vitamin E significantly enhanced endothelium-dependent vasodilatation in the radial circulation of patients with coronary artery disease. Its combination with vitamin E was superior to vitamin C administration alone for endothelial enhancement but this difference was not statistically significant. We hypothesised that vitamin C or its combination with vitamin E may be used as antioxidants for arterial graft patency in patients undergoing coronary artery surgery.
Asunto(s)
Antioxidantes/uso terapéutico , Ácido Ascórbico/uso terapéutico , Puente de Arteria Coronaria , Enfermedad de la Arteria Coronaria/cirugía , Arteria Radial/efectos de los fármacos , Vasodilatación/efectos de los fármacos , Vitamina E/uso terapéutico , Listas de Espera , Administración Oral , Adulto , Anciano , Antioxidantes/administración & dosificación , Ácido Ascórbico/administración & dosificación , Puente de Arteria Coronaria/métodos , Enfermedad de la Arteria Coronaria/diagnóstico , Quimioterapia Combinada , Femenino , Humanos , Masculino , Persona de Mediana Edad , Arteria Radial/diagnóstico por imagen , Arteria Radial/fisiopatología , Arteria Radial/trasplante , Factores de Tiempo , Recolección de Tejidos y Órganos , Resultado del Tratamiento , Turquía , Ultrasonografía , Grado de Desobstrucción Vascular/efectos de los fármacos , Vitamina E/administración & dosificaciónRESUMEN
An 86-year-old male patient with hypertension, Parkinsonism, benign prostatic hyperplasia, cataract and chronic obstructive pulmonary disease had a history of coronary bypass surgery in two veins due to anterior myocardial infarction one year earlier. He presented with pain and feelings of paresthesia below the knee of his left leg, and had fallen twice. He had used compressions and venoprotective medication for two years and had also received physiotherapy but it had not alleviated the symptoms. He had varicose dilatations in the left leg and pigmentation and a recovered venous ulcer scar were present on the medial malleolus. The patient was classed as grade 4 according to the CEAP classification. Because there was no deficiency in the superficial femoral and popliteal veins, the patient was taken for endovenous ablation. He had no pain or sensation of heaviness in the legs on postoperative day 10, and the first, third and sixth months of check up. Endovenous ablation is a procedure that increases the quality of life and comfort in elderly patients, with minimal pain. Radiofrequency catheter procedures have proven to be more successful in patients of all age groups than procedures such as standard surgery and foam therapy.