Detalles de la búsqueda
1.
Development of safe and antioxidant COX-2 inhibitors; Synthesis, molecular docking analysis and biological evaluation of novel pyrrolizine 5-carboxamides.
Bioorg Chem;
143: 107098, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38185010
2.
Probenecid ameliorates testosterone-induced benign prostatic hyperplasia: Implications of PGE-2 on ADAM-17/EGFR/ERK1/2 signaling cascade.
J Biochem Mol Toxicol;
37(11): e23450, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37352135
3.
Development of certain aminoquinazoline scaffolds as potential multitarget anticancer agents with apoptotic and anti-proliferative effects: Design, synthesis and biological evaluation.
Bioorg Chem;
135: 106496, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36989735
4.
Cyclooxygenase-2 activates EGFR-ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia.
Inflammopharmacology;
31(1): 499-516, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36586043
5.
Design and synthesis of new indole drug candidates to treat Alzheimer's disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy.
J Enzyme Inhib Med Chem;
37(1): 2660-2678, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36146947
6.
Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
Bioorg Chem;
116: 105394, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34619468
7.
New indomethacin analogs as selective COX-2 inhibitors: Synthesis, COX-1/2 inhibitory activity, anti-inflammatory, ulcerogenicity, histopathological, and docking studies.
Arch Pharm (Weinheim);
354(4): e2000328, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33314237
8.
Assessment of the Mechanistic Role of Cinnarizine in Modulating Experimentally-Induced Bronchial Asthma in Rats.
Pharmacology;
96(3-4): 167-74, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26304475
9.
Role of NF-κB/ICAM-1, JAK/STAT-3, and apoptosis signaling in the anticancer effect of tangeretin against urethane-induced lung cancer in BALB/c mice.
Life Sci;
325: 121749, 2023 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37142089
10.
Targeting SIRT1/FoxO3a/Nrf2 and PI3K/AKT Pathways with Rebamipide Attenuates Acetic Acid-Induced Colitis in Rats.
Pharmaceuticals (Basel);
16(4)2023 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37111290
11.
Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity.
Eur J Med Chem;
259: 115712, 2023 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37567059
12.
Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory pathways and PPAR-γ/SIRT1 cytoprotective signals.
Chem Biol Interact;
351: 109732, 2022 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34737150
13.
Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: Impact on oxidative stress and ACE2/Ang-(1-7) signaling.
Life Sci;
275: 119387, 2021 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33774027
14.
Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks.
Eur J Med Chem;
205: 112662, 2020 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32763463
15.
The potential effect of the angiotensin II receptor blocker telmisartan in regulating OVA-induced airway remodeling in experimental rats.
Pharmacol Rep;
67(5): 943-51, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26398389
Resultados
1 -
15
de 15
1
Próxima >
>>