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Biodemography Soc Biol ; 62(2): 198-207, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27337554

RESUMEN

Enterocolitis due to Clostridium difficile is major emerging cause of death in the U.S. Between 1999 and 2012, C. diff. deaths rose by a staggering almost ten-fold amount, to 7,739 from 793. This article has three goals. First, we present a demographic description of C. diff. mortality in the U.S. since 1999. Second, we test a hypothesis that the increase in C. diff. deaths is due to population aging. We find that the emergence of this cause of death follows a proportional hazard pattern above age 40. Thus, population aging is not the only factor responsible for the increase in C. diff. deaths. This, combined with a contributory cause of death analysis, points towards health care-based strategies to combat C. diff. Third, we demonstrate a simple weighted least squares technique for estimating Gompertz models that gives parameter estimates that are closer to full maximum likelihood than conventional approaches.


Asunto(s)
Factores de Edad , Causas de Muerte/tendencias , Clostridioides difficile/patogenicidad , Infecciones por Clostridium/mortalidad , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Infecciones por Clostridium/epidemiología , Femenino , Humanos , Lactante , Masculino , Persona de Mediana Edad , Modelos de Riesgos Proporcionales , Estados Unidos/epidemiología
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