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1.

The PI3K Pathway in Human Disease.

Fruman, David A; Chiu, Honyin; Hopkins, Benjamin D; Bagrodia, Shubha; Cantley, Lewis C; Abraham, Robert T.

Cell; 170(4): 605-635, 2017 Aug 10.

Artículo en Inglés | MEDLINE | ID: mdl-28802037

2.

Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.

Baltgalvis, Kristen A; Lamb, Kelsey N; Symons, Kent T; Wu, Chu-Chiao; Hoffman, Melissa A; Snead, Aaron N; Song, Xiaodan; Glaza, Thomas; Kikuchi, Shota; Green, Jason C; Rogness, Donald C; Lam, Betty; Rodriguez-Aguirre, Maria E; Woody, David R; Eissler, Christie L; Rodiles, Socorro; Negron, Seth M; Bernard, Steffen M; Tran, Eileen; Pollock, Jonathan; Tabatabaei, Ali; Contreras, Victor; Williams, Heather N; Pastuszka, Martha K; Sigler, John J; Pettazzoni, Piergiorgio; Rudolph, Markus G; Classen, Moritz; Brugger, Doris; Claiborne, Christopher; Plancher, Jean-Marc; Cuartas, Isabel; Seoane, Joan; Burgess, Laurence E; Abraham, Robert T; Weinstein, David S; Simon, Gabriel M; Patricelli, Matthew P; Kinsella, Todd M.

Nature; 629(8011): 435-442, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38658751

3.

Self-eating limits EGFR-dependent tumor growth.

Fantin, Valeria R; Abraham, Robert T.

Cell; 154(6): 1184-6, 2013 Sep 12.

Artículo en Inglés | MEDLINE | ID: mdl-24034240

4.

The Pten-Parkin Axis: At the Nexus of Cancer and Neurodegeneration.

Ihle, Nathan T; Abraham, Robert T.

Mol Cell; 65(6): 959-960, 2017 Mar 16.

Artículo en Inglés | MEDLINE | ID: mdl-28306509

5.

Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity.

Arensman, Michael D; Yang, Xiaoran S; Leahy, Danielle M; Toral-Barza, Lourdes; Mileski, Mary; Rosfjord, Edward C; Wang, Fang; Deng, Shibing; Myers, Jeremy S; Abraham, Robert T; Eng, Christina H.

Proc Natl Acad Sci U S A; 116(19): 9533-9542, 2019 05 07.

Artículo en Inglés | MEDLINE | ID: mdl-31019077

6.

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy.

Eng, Christina H; Wang, Zuncai; Tkach, Diane; Toral-Barza, Lourdes; Ugwonali, Savuth; Liu, Shanming; Fitzgerald, Stephanie L; George, Elizabeth; Frias, Elizabeth; Cochran, Nadire; De Jesus, Rowena; McAllister, Gregory; Hoffman, Gregory R; Bray, Kevin; Lemon, LuAnna; Lucas, Judy; Fantin, Valeria R; Abraham, Robert T; Murphy, Leon O; Nyfeler, Beat.

Proc Natl Acad Sci U S A; 113(1): 182-7, 2016 Jan 05.

Artículo en Inglés | MEDLINE | ID: mdl-26677873

7.

A metabolic (re-)balancing act.

Abraham, Robert T; Eng, Christina H.

Mol Cell; 38(4): 481-2, 2010 May 28.

Artículo en Inglés | MEDLINE | ID: mdl-20513422

8.

The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.

Zhang, You-Wei; Brognard, John; Coughlin, Chris; You, Zhongsheng; Dolled-Filhart, Marisa; Aslanian, Aaron; Manning, Gerard; Abraham, Robert T; Hunter, Tony.

Mol Cell; 35(4): 442-53, 2009 Aug 28.

Artículo en Inglés | MEDLINE | ID: mdl-19716789

9.

The PI3K, metabolic, and autophagy networks: interactive partners in cellular health and disease.

Shanware, Naval P; Bray, Kevin; Abraham, Robert T.

Annu Rev Pharmacol Toxicol; 53: 89-106, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23294306

10.

Moving out: mobilizing activated T cells from lymphoid tissues.

Berstein, Gabriel; Abraham, Robert T.

Nat Immunol; 9(5): 455-7, 2008 May.

Artículo en Inglés | MEDLINE | ID: mdl-18425096

11.

The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics.

Gerber, Hans-Peter; Koehn, Frank E; Abraham, Robert T.

Nat Prod Rep; 30(5): 625-39, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23525375

12.

Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.

Kemp, Michael G; Akan, Zafer; Yilmaz, Seçil; Grillo, Mary; Smith-Roe, Stephanie L; Kang, Tae-Hong; Cordeiro-Stone, Marila; Kaufmann, William K; Abraham, Robert T; Sancar, Aziz; Unsal-Kaçmaz, Keziban.

J Biol Chem; 285(22): 16562-71, 2010 May 28.

Artículo en Inglés | MEDLINE | ID: mdl-20233725

13.

Multimodal biomarker investigation on efficacy and mechanism of action for the mammalian target of rapamycin inhibitor, temsirolimus, in a preclinical mammary carcinoma OncoMouse model: a translational medicine study in support for early clinical development.

Wang, Xinkang; Zhan, Yutian; Zhao, Lei; Alvarez, John; Chaudhary, Inder; Zhou, Bin-Bing; Abraham, Robert T; Feuerstein, Giora Z.

J Pharmacol Exp Ther; 339(2): 421-9, 2011 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-21835932

14.

A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1.

Plattner, Rina; Irvin, Brenda J; Guo, Shuling; Blackburn, Kevin; Kazlauskas, Andrius; Abraham, Robert T; York, John D; Pendergast, Ann Marie.

Nat Cell Biol; 5(4): 309-19, 2003 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-12652307

15.

Sustained mTORC1 activity during palbociclib-induced growth arrest triggers senescence in ER+ breast cancer cells.

Maskey, Reeja S; Wang, Fang; Lehman, Elyssa; Wang, Yiqun; Emmanuel, Natasha; Zhong, Wenyan; Jin, Guixian; Abraham, Robert T; Arndt, Kim T; Myers, Jeremy S; Mazurek, Anthony.

Cell Cycle; 20(1): 65-80, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33356791

16.

Direct control of CAR T cells through small molecule-regulated antibodies.

Park, Spencer; Pascua, Edward; Lindquist, Kevin C; Kimberlin, Christopher; Deng, Xiaodi; Mak, Yvonne S L; Melton, Zea; Johnson, Theodore O; Lin, Regina; Boldajipour, Bijan; Abraham, Robert T; Pons, Jaume; Sasu, Barbra Johnson; Van Blarcom, Thomas J; Chaparro-Riggers, Javier.

Nat Commun; 12(1): 710, 2021 01 29.

Artículo en Inglés | MEDLINE | ID: mdl-33514714

17.

Differential regulation of TCR-mediated gene transcription by Vav family members.

Zakaria, Shaheen; Gomez, Timothy S; Savoy, Doris N; McAdam, Simon; Turner, Martin; Abraham, Robert T; Billadeau, Daniel D.

J Exp Med; 199(3): 429-34, 2004 Feb 02.

Artículo en Inglés | MEDLINE | ID: mdl-14757747

18.

Jurkat T cells and development of the T-cell receptor signalling paradigm.

Abraham, Robert T; Weiss, Arthur.

Nat Rev Immunol; 4(4): 301-8, 2004 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15057788

19.

Anti-tumor immunity influences cancer cell reliance upon ATG7.

Arensman, Michael D; Yang, Xiaoran S; Zhong, Wenyan; Bisulco, Stephanie; Upeslacis, Erik; Rosfjord, Edward C; Deng, Shibing; Abraham, Robert T; Eng, Christina H.

Oncoimmunology; 9(1): 1800162, 2020 08 23.

Artículo en Inglés | MEDLINE | ID: mdl-32923161

20.

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.

Villalba, Martin; Bi, Kun; Hu, Junru; Altman, Yoav; Bushway, Paul; Reits, Eric; Neefjes, Jacques; Baier, Gottfried; Abraham, Robert T; Altman, Amnon.

J Cell Biol; 157(2): 253-63, 2002 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-11956228

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