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1.

Biochemical characterization of the Eya and PP2A-B55α interaction.

Alderman, Christopher; Anderson, Ryan; Zhang, Lingdi; Hughes, Connor J; Li, Xueni; Ebmeier, Chris; Wagley, Marisa E; Ahn, Natalie G; Ford, Heide L; Zhao, Rui.

J Biol Chem; : 107408, 2024 May 23.

Artículo en Inglés | MEDLINE | ID: mdl-38796066

2.

Intermittent treatment of BRAF^V600E melanoma cells delays resistance by adaptive resensitization to drug rechallenge.

Kavran, Andrew J; Stuart, Scott A; Hayashi, Kristyn R; Basken, Joel M; Brandhuber, Barbara J; Ahn, Natalie G.

Proc Natl Acad Sci U S A; 119(12): e2113535119, 2022 03 22.

Artículo en Inglés | MEDLINE | ID: mdl-35290123

3.

Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol O-methyltransferase reaction.

Zhang, Jianyu; Balsbaugh, Jeremy L; Gao, Shuaihua; Ahn, Natalie G; Klinman, Judith P.

Proc Natl Acad Sci U S A; 117(20): 10797-10805, 2020 05 19.

Artículo en Inglés | MEDLINE | ID: mdl-32371482

4.

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

Masson, Glenn R; Burke, John E; Ahn, Natalie G; Anand, Ganesh S; Borchers, Christoph; Brier, Sébastien; Bou-Assaf, George M; Engen, John R; Englander, S Walter; Faber, Johan; Garlish, Rachel; Griffin, Patrick R; Gross, Michael L; Guttman, Miklos; Hamuro, Yoshitomo; Heck, Albert J R; Houde, Damian; Iacob, Roxana E; Jørgensen, Thomas J D; Kaltashov, Igor A; Klinman, Judith P; Konermann, Lars; Man, Petr; Mayne, Leland; Pascal, Bruce D; Reichmann, Dana; Skehel, Mark; Snijder, Joost; Strutzenberg, Timothy S; Underbakke, Eric S; Wagner, Cornelia; Wales, Thomas E; Walters, Benjamin T; Weis, David D; Wilson, Derek J; Wintrode, Patrick L; Zhang, Zhongqi; Zheng, Jie; Schriemer, David C; Rand, Kasper D.

Nat Methods; 16(7): 595-602, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31249422

5.

Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.

Pegram, Laurel M; Liddle, Jennifer C; Xiao, Yao; Hoh, Maria; Rudolph, Johannes; Iverson, Dylan B; Vigers, Guy P; Smith, Darin; Zhang, Hailong; Wang, Weiru; Moffat, John G; Ahn, Natalie G.

Proc Natl Acad Sci U S A; 116(31): 15463-15468, 2019 07 30.

Artículo en Inglés | MEDLINE | ID: mdl-31311868

6.

Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2.

Iverson, Dylan B; Xiao, Yao; Jones, David N; Eisenmesser, Elan Z; Ahn, Natalie G.

Biochemistry; 59(29): 2698-2706, 2020 07 28.

Artículo en Inglés | MEDLINE | ID: mdl-32643366

7.

Kinase Activation by Small Conformational Changes.

Lopez, Elias D; Burastero, Osvaldo; Arcon, Juan P; Defelipe, Lucas A; Ahn, Natalie G; Marti, Marcelo A; Turjanski, Adrian G.

J Chem Inf Model; 60(2): 821-832, 2020 02 24.

Artículo en Inglés | MEDLINE | ID: mdl-31714778

8.

Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.

Basken, Joel; Stuart, Scott A; Kavran, Andrew J; Lee, Thomas; Ebmeier, Christopher C; Old, William M; Ahn, Natalie G.

Mol Cell Proteomics; 17(4): 550-564, 2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29255136

9.

Quantitative functions of Argonaute proteins in mammalian development.

Wang, Dongmei; Zhang, Zhaojie; O'Loughlin, Evan; Lee, Thomas; Houel, Stephane; O'Carroll, Dónal; Tarakhovsky, Alexander; Ahn, Natalie G; Yi, Rui.

Genes Dev; 26(7): 693-704, 2012 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-22474261

10.

The case of the disappearing drug target.

Prince, John T; Ahn, Natalie G.

Mol Cell; 37(4): 455-6, 2010 Feb 26.

Artículo en Inglés | MEDLINE | ID: mdl-20188664

11.

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma.

Old, William M; Shabb, John B; Houel, Stephane; Wang, Hong; Couts, Kasey L; Yen, Chia-Yu; Litman, Elizabeth S; Croy, Carrie H; Meyer-Arendt, Karen; Miranda, Jose G; Brown, Robert A; Witze, Eric S; Schweppe, Rebecca E; Resing, Katheryn A; Ahn, Natalie G.

Mol Cell; 34(1): 115-31, 2009 Apr 10.

Artículo en Inglés | MEDLINE | ID: mdl-19362540

12.

A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.

Stuart, Scott A; Houel, Stephane; Lee, Thomas; Wang, Nan; Old, William M; Ahn, Natalie G.

Mol Cell Proteomics; 14(6): 1599-615, 2015 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-25850435

13.

Phosphorylation releases constraints to domain motion in ERK2.

Xiao, Yao; Lee, Thomas; Latham, Michael Parker; Warner, Lisa Rose; Tanimoto, Akiko; Pardi, Arthur; Ahn, Natalie G.

Proc Natl Acad Sci U S A; 111(7): 2506-11, 2014 Feb 18.

Artículo en Inglés | MEDLINE | ID: mdl-24550275

14.

Dynamics of protein kinases: insights from nuclear magnetic resonance.

Xiao, Yao; Liddle, Jennifer C; Pardi, Arthur; Ahn, Natalie G.

Acc Chem Res; 48(4): 1106-14, 2015 Apr 21.

Artículo en Inglés | MEDLINE | ID: mdl-25803188

15.

Slow inhibition and conformation selective properties of extracellular signal-regulated kinase 1 and 2 inhibitors.

Rudolph, Johannes; Xiao, Yao; Pardi, Arthur; Ahn, Natalie G.

Biochemistry; 54(1): 22-31, 2015 Jan 13.

Artículo en Inglés | MEDLINE | ID: mdl-25350931

16.

Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2.

Xiao, Yao; Warner, Lisa R; Latham, Michael P; Ahn, Natalie G; Pardi, Arthur.

Biochemistry; 54(28): 4307-19, 2015 Jul 21.

Artículo en Inglés | MEDLINE | ID: mdl-26132046

17.

The p38ß mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.

Beenstock, Jonah; Ben-Yehuda, Sheer; Melamed, Dganit; Admon, Arie; Livnah, Oded; Ahn, Natalie G; Engelberg, David.

J Biol Chem; 289(34): 23546-56, 2014 Aug 22.

Artículo en Inglés | MEDLINE | ID: mdl-25006254

18.

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate ß-tubulin folding.

Tracy, Christopher M; Gray, Amy J; Cuéllar, Jorge; Shaw, Tanner S; Howlett, Alyson C; Taylor, Ryan M; Prince, John T; Ahn, Natalie G; Valpuesta, José M; Willardson, Barry M.

J Biol Chem; 289(7): 4490-502, 2014 Feb 14.

Artículo en Inglés | MEDLINE | ID: mdl-24375412

19.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

Miller, Suzannah G; Hoh, Maria; Ebmeier, Christopher C; Tay, Jian Wei; Ahn, Natalie G.

Mol Biol Cell; 35(3): ar31, 2024 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-38117590

20.

Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2.

Anderson, Jake W; Vaisar, David; Jones, David N; Pegram, Laurel M; Vigers, Guy P; Chen, Huifen; Moffat, John G; Ahn, Natalie G.

Elife; 122024 Mar 27.

Artículo en Inglés | MEDLINE | ID: mdl-38537148

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