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1.

The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells.

Ng, Charles; Aichinger, Martin; Nguyen, Tung; Au, Christy; Najar, Tariq; Wu, Lin; Mesa, Kai R; Liao, Will; Quivy, Jean-Pierre; Hubert, Benjamin; Almouzni, Genevieve; Zuber, Johannes; Littman, Dan R.

Genes Dev; 33(11-12): 669-683, 2019 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-30975723

2.

Human blood vessel organoids as a model of diabetic vasculopathy.

Wimmer, Reiner A; Leopoldi, Alexandra; Aichinger, Martin; Wick, Nikolaus; Hantusch, Brigitte; Novatchkova, Maria; Taubenschmid, Jasmin; Hämmerle, Monika; Esk, Christopher; Bagley, Joshua A; Lindenhofer, Dominik; Chen, Guibin; Boehm, Manfred; Agu, Chukwuma A; Yang, Fengtang; Fu, Beiyuan; Zuber, Johannes; Knoblich, Juergen A; Kerjaschki, Dontscho; Penninger, Josef M.

Nature; 565(7740): 505-510, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-30651639

3.

Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin, Shane J F; Seehus, Corey; Weidinger, Adelheid; Talbot, Sebastien; Reissig, Sonja; Seifert, Markus; Pierson, Yann; McNeill, Eileen; Longhi, Maria Serena; Turnes, Bruna Lenfers; Kreslavsky, Taras; Kogler, Melanie; Hoffmann, David; Ticevic, Melita; da Luz Scheffer, Débora; Tortola, Luigi; Cikes, Domagoj; Jais, Alexander; Rangachari, Manu; Rao, Shuan; Paolino, Magdalena; Novatchkova, Maria; Aichinger, Martin; Barrett, Lee; Latremoliere, Alban; Wirnsberger, Gerald; Lametschwandtner, Guenther; Busslinger, Meinrad; Zicha, Stephen; Latini, Alexandra; Robson, Simon C; Waisman, Ari; Andrews, Nick; Costigan, Michael; Channon, Keith M; Weiss, Guenter; Kozlov, Andrey V; Tebbe, Mark; Johnsson, Kai; Woolf, Clifford J; Penninger, Josef M.

Nature; 572(7769): E18, 2019 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-31363232

4.

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin, Shane J F; Seehus, Corey; Weidinger, Adelheid; Talbot, Sebastien; Reissig, Sonja; Seifert, Markus; Pierson, Yann; McNeill, Eileen; Longhi, Maria Serena; Turnes, Bruna Lenfers; Kreslavsky, Taras; Kogler, Melanie; Hoffmann, David; Ticevic, Melita; da Luz Scheffer, Débora; Tortola, Luigi; Cikes, Domagoj; Jais, Alexander; Rangachari, Manu; Rao, Shuan; Paolino, Magdalena; Novatchkova, Maria; Aichinger, Martin; Barrett, Lee; Latremoliere, Alban; Wirnsberger, Gerald; Lametschwandtner, Guenther; Busslinger, Meinrad; Zicha, Stephen; Latini, Alexandra; Robson, Simon C; Waisman, Ari; Andrews, Nick; Costigan, Michael; Channon, Keith M; Weiss, Guenter; Kozlov, Andrey V; Tebbe, Mark; Johnsson, Kai; Woolf, Clifford J; Penninger, Josef M.

Nature; 563(7732): 564-568, 2018 11.

Artículo en Inglés | MEDLINE | ID: mdl-30405245

5.

Pharmacodynamic and Antitumor Activity of BI 836880, a Dual Vascular Endothelial Growth Factor and Angiopoietin 2 Inhibitor, Alone and Combined with Programmed Cell Death Protein-1 Inhibition.

Hofmann, Irmgard; Baum, Anke; Hofmann, Marco H; Trapani, Francesca; Reichel-Voda, Claudia; Ehrensperger, Diane; Aichinger, Martin; Ebner, Florian; Budano, Nicole; Schweifer, Norbert; Sykora, Martina; Depla, Erik; Boucneau, Joachim; Gschwind, Andreas; Kraut, Norbert; Hilberg, Frank; Künkele, Klaus-Peter.

J Pharmacol Exp Ther; 384(3): 331-342, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36241203

6.

Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance.

Hinterberger, Maria; Aichinger, Martin; Prazeres da Costa, Olivia; Voehringer, David; Hoffmann, Reinhard; Klein, Ludger.

Nat Immunol; 11(6): 512-9, 2010 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-20431619

7.

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.

Michlits, Georg; Hubmann, Maria; Wu, Szu-Hsien; Vainorius, Gintautas; Budusan, Elena; Zhuk, Sergei; Burkard, Thomas R; Novatchkova, Maria; Aichinger, Martin; Lu, Yiqing; Reece-Hoyes, John; Nitsch, Roberto; Schramek, Daniel; Hoepfner, Dominic; Elling, Ulrich.

Nat Methods; 14(12): 1191-1197, 2017 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-29039415

8.

Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance.

Klein, Ludger; Hinterberger, Maria; von Rohrscheidt, Julia; Aichinger, Martin.

Trends Immunol; 32(5): 188-93, 2011 May.

Artículo en Inglés | MEDLINE | ID: mdl-21493141

9.

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.

Nedjic, Jelena; Aichinger, Martin; Emmerich, Jan; Mizushima, Noboru; Klein, Ludger.

Nature; 455(7211): 396-400, 2008 Sep 18.

Artículo en Inglés | MEDLINE | ID: mdl-18701890

10.

Tumor microenvironment mimicking 3D models unveil the multifaceted effects of SMAC mimetics.

Pinto, Catarina; Slavic-Obradovic, Ksenija; Fürweger, Daniela; Thaler, Barbara; Souabni, Abdallah; Carotta, Sebastian; Aichinger, Martin; Reiser, Ulrich; Impagnatiello, Maria Antonietta; Tirapu, Iñigo.

iScience; 26(4): 106381, 2023 Apr 21.

Artículo en Inglés | MEDLINE | ID: mdl-37009211

11.

VÎ³9VÎ´2 T Cells: Can We Re-Purpose a Potent Anti-Infection Mechanism for Cancer Therapy?

Künkele, Klaus-Peter; Wesch, Daniela; Oberg, Hans-Heinrich; Aichinger, Martin; Supper, Verena; Baumann, Christoph.

Cells; 9(4)2020 03 30.

Artículo en Inglés | MEDLINE | ID: mdl-32235616

12.

Generation of blood vessel organoids from human pluripotent stem cells.

Wimmer, Reiner A; Leopoldi, Alexandra; Aichinger, Martin; Kerjaschki, Dontscho; Penninger, Josef M.

Nat Protoc; 14(11): 3082-3100, 2019 11.

Artículo en Inglés | MEDLINE | ID: mdl-31554955

13.

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

Skucha, Anna; Ebner, Jessica; Schmöllerl, Johannes; Roth, Mareike; Eder, Thomas; César-Razquin, Adrián; Stukalov, Alexey; Vittori, Sarah; Muhar, Matthias; Lu, Bin; Aichinger, Martin; Jude, Julian; Müller, André C; Gyorffy, Balázs; Vakoc, Christopher R; Valent, Peter; Bennett, Keiryn L; Zuber, Johannes; Superti-Furga, Giulio; Grebien, Florian.

Nat Commun; 9(1): 1983, 2018 05 18.

Artículo en Inglés | MEDLINE | ID: mdl-29777171

14.

Thymic epithelial cells use macroautophagy to turn their inside out for CD4 T cell tolerance.

Wu, Chunyan; Aichinger, Martin; Nedjic, Jelena; Klein, Ludger.

Autophagy; 9(6): 931-2, 2013 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-23548947

15.

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance.

Aichinger, Martin; Wu, Chunyan; Nedjic, Jelena; Klein, Ludger.

J Exp Med; 210(2): 287-300, 2013 Feb 11.

Artículo en Inglés | MEDLINE | ID: mdl-23382543

16.

Probing gene function in thymic epithelial cells.

Aichinger, Martin; Hinterberger, Maria; Klein, Ludger.

Eur J Cell Biol; 91(1): 24-30, 2012 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-21392839

17.

Loss of Roquin induces early death and immune deregulation but not autoimmunity.

Bertossi, Arianna; Aichinger, Martin; Sansonetti, Paola; Lech, Maciej; Neff, Frauke; Pal, Martin; Wunderlich, F Thomas; Anders, Hans-Joachim; Klein, Ludger; Schmidt-Supprian, Marc.

J Exp Med; 208(9): 1749-56, 2011 Aug 29.

Artículo en Inglés | MEDLINE | ID: mdl-21844204

18.

Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules.

Nedjic, Jelena; Aichinger, Martin; Mizushima, Noboru; Klein, Ludger.

Curr Opin Immunol; 21(1): 92-7, 2009 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-19246181

19.

Autophagy and T cell education in the thymus: eat yourself to know yourself.

Nedjic, Jelena; Aichinger, Martin; Klein, Ludger.

Cell Cycle; 7(23): 3625-8, 2008 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-19029805

20.

A novel role for autophagy in T cell education.