Detalles de la búsqueda
1.
Identification of novel ureido benzothiophenes as dual VEGFR-2/EGFR anticancer agents.
Bioorg Chem;
143: 107037, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38134521
2.
Design and synthesis of benzo[b]thiophene-based hybrids as novel antitubercular agents against MDR/XDR Mycobacterium tuberculosis.
Arch Pharm (Weinheim);
357(2): e2300529, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37946574
3.
Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt.
J Enzyme Inhib Med Chem;
38(1): 2224944, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37369580
4.
Biological evaluation, docking studies, and in silico ADME prediction of some pyrimidine and pyridine derivatives as potential EGFRWT and EGFRT790M inhibitors.
J Enzyme Inhib Med Chem;
38(1): 176-191, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36317648
5.
Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators.
J Enzyme Inhib Med Chem;
38(1): 2157825, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36629421
6.
1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights.
Molecules;
28(7)2023 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37049966
7.
GC-MS metabolites profiling of anethole-rich oils by different extraction techniques: antioxidant, cytotoxicity and in-silico enzymes inhibitory insights.
J Enzyme Inhib Med Chem;
37(1): 1974-1986, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35850583
8.
Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment.
J Enzyme Inhib Med Chem;
37(1): 2256-2264, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36000171
9.
Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights.
J Enzyme Inhib Med Chem;
37(1): 1227-1240, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35470754
10.
Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII.
J Enzyme Inhib Med Chem;
37(1): 2635-2643, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36146927
11.
Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms.
J Enzyme Inhib Med Chem;
37(1): 531-541, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34991416
12.
Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis.
Molecules;
27(24)2022 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36557937
13.
Synthesis and Biological Activity Screening of Newly Synthesized Trimethoxyphenyl-Based Analogues as Potential Anticancer Agents.
Molecules;
27(14)2022 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35889493
14.
Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells.
Molecules;
27(12)2022 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35745081
15.
Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations.
Bioorg Chem;
110: 104748, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33684714
16.
Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3ß inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies.
J Enzyme Inhib Med Chem;
36(1): 270-285, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33327806
17.
Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer.
J Enzyme Inhib Med Chem;
36(1): 1424-1435, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34176414
18.
Development of novel isatin-nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing-bacteria.
J Enzyme Inhib Med Chem;
36(1): 384-393, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33406941
19.
Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells.
J Enzyme Inhib Med Chem;
36(1): 319-328, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33345633
20.
Recent advancements of coumarin-based anticancer agents: An up-to-date review.
Bioorg Chem;
103: 104163, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32890989