Stroke during sleep and obstructive sleep apnea: there is a link.

OBJECTIVES: The onset of ischemic stroke symptoms has been established to have a diurnal variation, with a sizeable proportion (8-28%) occurring during sleep. Obstructive sleep apnea (OSA) has been established as an important risk factor for ischemic stroke. However, data on the relationship between OSA and wake-up stroke (WUS) has been scarce. The aim of our study is to determine the relationship between OSA and WUS. METHODS: This is a case-control study conducted on acute stroke patients who presented to one of two major medical centers in Riyadh of Saudi Arabia. Those who woke up with the symptoms were labeled as WUS, and those whose stroke occurred while awake were labeled as non wake-up stroke (NWUS). The Berlin Questionnaire, which was submitted to either the patient or his/her partner, was used to determine the frequency of OSA in the two groups. RESULTS: One hundred seven patients (60% males) with acute stroke were admitted between March 2016 and March 2017. Of the 40 patients with WUS, 29 (72.5%) had underlying OSA based on the Berlin Questionnaire, whereas only 30 (45%) of the 67 patients with NWUS have underlying OSA. Logistic regression analysis showed OSA is highly prevalent in the patients with WUS (OR = 3.25; 95% CI = 1.397-8.38; p = 0.0053). CONCLUSION: OSA is an important risk factor for ischemic stroke during sleep. Health care providers must be vigilant in inquiring about symptoms suggestive of OSA in every ischemic stroke patient, especially the patient whose stroke occurred during sleep.

Prevalence and Determinants of Vaccine Hesitancy in Aseer Region, Saudi Arabia.

OBJECTIVES: This study aimed to assess the awareness of the general population regarding vaccines to determine the prevalence of vaccine hesitancy in Aseer Region in the southern part of Saudi Arabia. METHODS: A descriptive cross-sectional approach was used, targeting all parents in Aseer Region. The study was carried out from January to April 2020. The data for this study were collected using a structured questionnaire, which was developed by the researchers after an intensive literature review and consultation with experts. The questionnaire covered aspects such as parents' sociodemographic data, their awareness regarding vaccine safety and efficacy for children and their attitude and adherence to children's vaccination, including their hesitancy towards vaccines. RESULTS: The survey included 796 participants (response rate: 100%) whose ages ranged from 18 to 55 years. Two-thirds (63.4%) of the participants were female. Regarding vaccination adherence and hesitancy among participants, more than three-quarters completely adhered to the vaccination schedule for their children, and only 3.9% were non-adherent. With regards to participants' awareness regarding vaccine safety and efficacy for children, 89.3% agreed that vaccination keeps children healthy, 84.2% reported that vaccines are safe and effective for children and 83.4% reported that all scheduled vaccines in Saudi Arabia are effective. CONCLUSION: Vaccine hesitancy among participants was not low, and this should be taken into account notwithstanding their high awareness levels. The recorded antivaccine action was mostly related to vaccine safety and not its efficacy.

Assessing knowledge and practice about eye injuries first aid, with awareness about the importance of early management among general population in Asser Region, 2020.

BACKGROUND: Eye injury is a leading cause of monocular blindness and is second only to cataract as the commonest cause of visual impairment. Injury is the commonest reason for eye-related emergency department visits. AIM: To assess population awareness regarding eye injuries first aids in Aseer region, Saudi Arabia. METHODOLOGY: A descriptive cross-sectional approach was used targeting all accessible population in Aseer region, Southern of Saudi Arabia. Data were collected from participants using electronic pre-structured questionnaire. The tool will cover participants' socio-demographic data, participants' history of eye injury, awareness and practice regarding different types of eye injuries first aids. RESULTS: The survey included 1213 participants who completed the questionnaire. Participants' ages ranged from 18 to 60 years old with mean age of 22.3 ± 11.9 years old. About 69% of the participants reported for having constant eye pain, 68.3% reported in case of Foreign Body (FB) in the eye, 66.9% reported for torn eye lid. Regarding signs of scratch eye, 64.2% reported for feel FB inside, 58% reported for eye pain and 55.2% reported for blurred vision. Exact of 25.7% of participants reported that they should blink several times in case of getting eye scratch, whereas 77.8% reported that they should rub the eye to try to remove any foreign object, 36.3% preferred to use the soothing eye drop. CONCLUSIONS: In conclusion, the study revealed that public awareness regarding eye injury first aid in Aseer region was poor especially for chemical injuries. Physician role should be augmented and health education campaigns are advised.