Is quality of life associated with compliance to pharmacoterapy in patients with chronic kidney disease undergoing maintenance hemodialysis?

Objective To analyzed the association of quality of life and compliance to drug treatment in chronic kidney disease patients. Methods The Short Form Health Survey was used to evaluate the quality of life of these patients, and the therapeutic complexity index was verified. The Morisky-Green test and the Brief Medication Questionnaire were applied to check compliance to drug therapy. Results A total of 197 patients were included. The Morisky-Green test and Brief Medication Questionnaire showed that most patients had low compliance to treatment (50.3% and 80.6%, respectively). Compliance was highly associated with gender (male) and slightly associated with complexity of therapy, mental health, and social aspects. Conclusion We observed a slight association between compliance to pharmacotherapy and quality of life and complexity of therapy, and a strong association with gender.

Is quality of life associated with compliance to pharmacoterapy in patients with chronic kidney disease undergoing maintenance hemodialysis? / Existe associação entre qualidade de vida e adesão à farmacoterapia em pacientes com doença renal crônica em hemodiálise?

ABSTRACT Objective To analyzed the association of quality of life and compliance to drug treatment in chronic kidney disease patients. Methods The Short Form Health Survey was used to evaluate the quality of life of these patients, and the therapeutic complexity index was verified. The Morisky-Green test and the Brief Medication Questionnaire were applied to check compliance to drug therapy. Results A total of 197 patients were included. The Morisky-Green test and Brief Medication Questionnaire showed that most patients had low compliance to treatment (50.3% and 80.6%, respectively). Compliance was highly associated with gender (male) and slightly associated with complexity of therapy, mental health, and social aspects. Conclusion We observed a slight association between compliance to pharmacotherapy and quality of life and complexity of therapy, and a strong association with gender.

RESUMO Objetivo Analisar a associação entre a qualidade de vida e a adesão ao tratamento farmacológico de pacientes com doença renal crônica. Métodos Utilizou-se o Short Form Health Survey para avaliar a qualidade de vida destes pacientes. O índice de complexidade terapêutico foi avaliado. O teste de Morisky-Green e o Brief Medication Questionnaire foram aplicados para avaliar a adesão a farmacoterapia. Resultados Nos 197 pacientes que participaram do estudo, o teste de Morisky-Green e o Brief Medication Questionnaire mostraram que a maioria deles apresentava baixa adesão ao tratamento (50,3% e 80,6%, respectivamente). A adesão esteve altamente associada ao sexo (masculino) e ligeiramente associada à complexidade da terapia, à saúde mental e aos aspectos sociais. Conclusão Observaram-se ligeira associação da adesão farmacoterapêutica com qualidade de vida e complexidade terapêutica, e forte associação com o sexo.