Detalles de la búsqueda
1.
Human iPSC-Derived 2D and 3D Platforms for Rapidly Assessing Developmental, Functional, and Terminal Toxicities in Neural Cells.
Int J Mol Sci;
22(4)2021 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33672998
2.
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.
Toxicol Appl Pharmacol;
322: 60-74, 2017 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28259702
3.
Transcriptional Variabilities in Human hiPSC-derived Cardiomyocytes: All Genes Are Not Equal and Their Robustness May Foretell Donor's Disease Susceptibility.
bioRxiv;
2024 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38659937
4.
High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.
Am J Physiol Heart Circ Physiol;
301(5): H2006-17, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21890694
5.
Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
Am J Physiol Heart Circ Physiol;
298(6): H1842-9, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20363883
6.
Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids.
PLoS One;
15(10): e0240991, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33091047
7.
A human population-based organotypic in vitro model for cardiotoxicity screening.
ALTEX;
35(4): 441-452, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29999168
8.
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study.
Toxicol Sci;
164(2): 550-562, 2018 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29718449
9.
Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Circulation;
113(3): 365-73, 2006 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-16432067
10.
Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery.
Cell Chem Biol;
24(5): 624-634.e3, 2017 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28434878
11.
Blockade of HERG channels by HIV protease inhibitors.
Lancet;
365(9460): 682-6, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15721475
12.
Comparison of HERG channel blocking effects of various beta-blockers-- implication for clinical strategy.
Br J Pharmacol;
147(6): 642-52, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16314852
13.
Biology of cardiac arrhythmias: ion channel protein trafficking.
Circ Res;
94(11): 1418-28, 2004 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-15192037
14.
Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells in Phenotypic Screening: A Transforming Growth Factor-ß Type 1 Receptor Kinase Inhibitor Induces Efficient Cardiac Differentiation.
Stem Cells Transl Med;
5(2): 164-74, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26683871
15.
Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes.
Toxicol Sci;
154(1): 174-182, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27503387
16.
Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.
Circulation;
105(24): 2830-5, 2002 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-12070109
17.
An intronic mutation causes long QT syndrome.
J Am Coll Cardiol;
44(6): 1283-91, 2004 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15364333
18.
Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes.
Tissue Eng Part C Methods;
21(8): 852-61, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25654582
19.
Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy.
J Biomol Screen;
18(10): 1203-11, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24071917
20.
Comparative gene expression profiling in human-induced pluripotent stem cell--derived cardiocytes and human and cynomolgus heart tissue.
Toxicol Sci;
131(1): 292-301, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22982684