[Are hybrid technologies appropriate for revascularization of aortoiliac-femoral segment?] / Opravdano li primenenie gibridnykh tekhnologii pri revaskulyarizatsii aorto-podvzdoshno-bedrennogo segmenta.

OBJECTIVE: To compare various approaches to revascularization of aortoiliac-femoral segment. MATERIAL AND METHODS: Data were collected prospectively for retrospective analysis. There were 192 patients with atherosclerotic lesion of the aortoiliac-femoral segment who underwent reconstructive surgeries. All patients were divided into 3 groups depending on the type of reconstruction: 85 patients underwent open surgical interventions, 63 patients - endovascular interventions, 44 patients - hybrid techniques. Between-group differences were considered significant at p-value <0.05. RESULTS: Hybrid revascularization is characterized by less duration of surgery, blood loss and morbidity. Hybrid interventions ensured favorable primary patency compared to open surgery within the follow-up period. CONCLUSION: Hybrid revascularization of aortoiliac-femoral segment is characterized by less duration of surgery, blood loss and morbidity.

Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice.

Traumatic brain injury (TBI) can result in long-lasting changes in hippocampal function. The changes induced by TBI on the hippocampus contribute to cognitive deficits. The adult hippocampus harbors neural stem cells (NSCs) that generate neurons (neurogenesis), and astrocytes (astrogliogenesis). While deregulation of hippocampal NSCs and neurogenesis have been observed after TBI, it is not known how TBI may affect hippocampal astrogliogenesis. Using a controlled cortical impact model of TBI in male mice, single cell RNA sequencing and spatial transcriptomics, we assessed how TBI affected hippocampal NSCs and the neuronal and astroglial lineages derived from them. We observe an increase in NSC-derived neuronal cells and a concomitant decrease in NSC-derived astrocytic cells, together with changes in gene expression and cell dysplasia within the dentate gyrus. Here, we show that TBI modifies NSC fate to promote neurogenesis at the cost of astrogliogenesis and identify specific cell populations as possible targets to counteract TBI-induced cellular changes in the adult hippocampus.

Search for a Higgs boson in the diphoton final state in pp collisions at sqrt[s]=1.96 TeV.

A search for a narrow Higgs boson resonance in the diphoton mass spectrum is presented based on data corresponding to 7.0 fb{-1} of integrated luminosity from pp collisions at sqrt[s]=1.96 TeV collected by the CDF experiment. No evidence of such a resonance is observed, and upper limits are set on the cross section times branching ratio of the resonant state as a function of Higgs boson mass. The limits are interpreted in the context of the standard model and one fermiophobic benchmark model where the data exclude fermiophobic Higgs bosons with masses below 114 GeV/c{2} at a 95% Bayesian credibility level.

Measurements of the angular distributions in the decays B→K(*)µ(+)µ(-) at CDF.

We report an indirect search for nonstandard model physics using the flavor-changing neutral current decays B→K(*)µ(+)µ(-). We reconstruct the decays and measure their angular distributions, as a function of q(2)=M(µµ)(2)c(2), where M(µµ) is the dimuon mass, in pp¯ collisions at √s=1.96 TeV using a data sample corresponding to an integrated luminosity of 6.8 fb(-1). The transverse polarization asymmetry A(T)(2) and the time-reversal-odd charge-and-parity asymmetry A(im) are measured for the first time, together with the K* longitudinal polarization fraction F(L) and the muon forward-backward asymmetry A(FB) for the decays B(0)→K(*0)µ(+)µ(-) and B(+)→K(*+)µ(+)µ(-). The B→K*µ(+)µ(-) forward-backward asymmetry in the most sensitive kinematic regime, 1≤q(2)<6 GeV(2)/c(2), is measured to be A(FB)=0.29(-0.23)(+0.20)(stat)±0.07(syst), the most precise result to date. No deviations from the standard model predictions are observed.

Search for a low-mass standard model Higgs boson in the ττ decay channel in pp collisions at sqrt[s]=1.96 TeV.

We report on a search for the standard model Higgs boson decaying into pairs of τ leptons in pp collisions produced by the Tevatron at sqrt[s]=1.96 TeV. The analyzed data sample was recorded by the CDFII detector and corresponds to an integrated luminosity of 6.0 fb(-1). The search is performed in the final state with one τ decaying leptonically and the second one identified through its semihadronic decay. Since no significant excess is observed, a 95% credibility level upper limit on the production cross section times branching ratio to the ττ final state is set for hypothetical Higgs boson masses between 100 and 150 GeV/c2. For a Higgs boson of 120 GeV/c2 the observed (expected) limit is 14.6 (15.3) the predicted value.

Search for high mass resonances decaying to muon pairs in √s=1.96 TeV pp collisions.

We present a search for a new narrow, spin-1, high mass resonance decaying to µ(+)µâ»+X, using a matrix-element-based likelihood and a simultaneous measurement of the resonance mass and production rate. In data with 4.6 fb⁻¹ of integrated luminosity collected by the CDF detector in pp collisions at √s=1960 GeV, the most likely signal cross section is consistent with zero at 16% confidence level. We therefore do not observe evidence for a high mass resonance and place limits on models predicting spin-1 resonances, including M>1071 GeV/c² at 95% confidence level for a Z' boson with the same couplings to fermions as the Z boson.

Measurement of b hadron lifetimes in exclusive decays containing a J/ψ in pp collisions at √s=1.96 TeV.

We report on a measurement of b-hadron lifetimes in the fully reconstructed decay modes B(+)→J/ψK(+), B°â†’J/ψK*(892)°, B°â†’J/ψK(s)°, and Λ(b)°â†’J/ψΛ° using data corresponding to an integrated luminosity of 4.3 fb⁻¹, collected by the CDF II detector at the Fermilab Tevatron. The measured lifetimes are τ(B(+))=[1.639±0.009(stat)±0.009(syst)] ps, τ(B°)=[1.507±0.010(stat)±0.008(syst)] ps, and τ(Λ(b)°)=[1.537±0.045(stat)±0.014(syst)] ps. The lifetime ratios are τ(B(+))/τ(B°)=[1.088±0.009(stat)±0.004(syst)] and τ(Λ(b)°)/τ(B°)=[1.020±0.030(stat)±0.008(syst)]. These are the most precise determinations of these quantities from a single experiment.

Search for heavy bottomlike quarks decaying to an electron or muon and jets in pp collisions at √s = 1.96 TeV.

We report the most sensitive direct search for pair production of fourth-generation bottomlike chiral quarks (b') each decaying promptly to tW. We search for an excess of events with an electron or muon, at least five jets (one identified as due to a b or c quark), and an imbalance of transverse momentum by using data from pp collisions collected by the CDF II detector at Fermilab with an integrated luminosity of 4.8 fb(-1). We observe events consistent with background expectation, calculate upper limits on the b' pair-production cross section (σ(bb')) ≲30 fb for m(b') > 375 GeV/c2), and exclude m(b') < 372 GeV/c2 at 95% confidence level assuming a 100% branching ratio of b' to tW.

First measurement of the angular coefficients of Drell-Yan e(+)e(-) pairs in the Z mass region from pp¯ collisions at √s=1.96 TeV.

We report on the first measurement of the angular distributions of final state electrons in pp¯ → γ*/Z → e(+)e(-) + X events produced in the Z boson mass region at √s1.96 TeV. The data sample collected by the CDF II detector for this result corresponds to 2.1 fb(-1) of integrated luminosity. The angular distributions are studied as a function of the transverse momentum of the electron-positron pair and show good agreement with the Lam-Tung relation, consistent with a spin-1 description of the gluon, and demonstrate that, at high values of the transverse momentum, Z bosons are produced via quark-antiquark annihilation and quark-gluon Compton processes.

Measurement of the forward-backward asymmetry in the B→K*µ(+)µ(-) decay and first observation of the B(s)0→ϕµ(+)µ(-) decay.

We reconstruct the rare decays B(+)→K(+)µ(+0µ(-0, B90)→K*(892)(0)µ(+)µ(-), and B(s)(0)→ϕ(1020)µ(+)µ(-) in a data sample corresponding to 4.4 fb(-1) collected in pp collisions at √[s]=1.96 TeV by the CDF II detector at the Tevatron Collider. Using 121±16 B(+)→K(+)µ(+)µ(-) and 101±12 B(0)→K(*0)µ(+)µ(-) decays we report the branching ratios. In addition, we report the differential branching ratio and the muon forward-backward asymmetry in the B(+) and B(0) decay modes, and the K(*0) longitudinal polarization fraction in the B(0) decay mode with respect to the squared dimuon mass. These are consistent with the predictions, and most recent determinations from other experiments and of comparable accuracy. We also report the first observation of the B(s)(0)→ϕµ(+)µ(-) decay and measure its branching ratio BR(B(s)(0)→ϕµ(+)µ(-))=[1.44±0.33±0.46]×10(-6) using 27±6 signal events. This is currently the most rare B(s)(0) decay observed.

Measurement of the mass difference between t and t quarks.

We present a direct measurement of the mass difference between t and t quarks using tt candidate events in the lepton+jets channel, collected with the CDF II detector at Fermilab's 1.96 TeV Tevatron pp Collider. We make an event by event estimate of the mass difference to construct templates for top quark pair signal events and background events. The resulting mass difference distribution of data is compared to templates of signals and background using a maximum likelihood fit. From a sample corresponding to an integrated luminosity of 5.6 fb(-1), we measure a mass difference, ΔM(top) = M(t) - M(t) = -3.3 ± 1.4(stat) ± 1.0(syst) GeV/c2, approximately 2 standard deviations away from the CPT hypothesis of zero mass difference.

Invariant mass distribution of jet pairs produced in association with a W boson in pp collisions at sqrt[s]=1.96 TeV.

We report a study of the invariant mass distribution of jet pairs produced in association with a W boson using data collected with the CDF detector which correspond to an integrated luminosity of 4.3 fb(-1). The observed distribution has an excess in the 120-160 GeV/c(2) mass range which is not described by current theoretical predictions within the statistical and systematic uncertainties. In this Letter, we report studies of the properties of this excess.

Measurements of direct CP violating asymmetries in charmless decays of strange bottom mesons and bottom baryons.

We report measurements of direct CP-violating asymmetries in charmless decays of neutral bottom hadrons to pairs of charged hadrons with the upgraded Collider Detector at the Fermilab Tevatron. Using a data sample corresponding to 1 fb(-1) of integrated luminosity, we obtain the first measurements of direct CP violation in bottom strange mesons, A(CP)(B(s)(0)→K(-)π(+))=+0.39±0.15(stat)±0.08(syst), and bottom baryons, A(CP)(Λ(b)(0)→pπ(-))=+0.03±0.17(stat)±0.05(syst) and A(CP)(Λ(b)(0)→pK(-))=+0.37±0.17(stat)±0.03(syst). In addition, we measure CP violation in B(0)→K(+)π(-) decays with 3.5σ significance, A(CP)(B(0)→K(+)π(-))=-0.086±0.023(stat)±0.009(syst), in agreement with the current world average. Measurements of branching fractions of B(s)(0)→K(+)K(-) and B(0)→π(+)π(-) decays are also updated.

Search for production of heavy particles decaying to top quarks and invisible particles in pp collisions at √s = 1.96 TeV.

We present a search for a new particle T' decaying to top quark via T' → t + X, where X is an invisible particle. In a data sample with 4.8 fb(-1) of integrated luminosity collected by the CDF II detector at Fermilab in pp collisions with √s = 1.96 TeV, we search for pair production of T' in the lepton + jets channel, pp → tt + X + X → ℓνbqq'b + X + X. We interpret our results primarily in terms of a model where T' are exotic fourth generation quarks and X are dark matter particles. Current direct and indirect bounds on such exotic quarks restrict their masses to be between 300 and 600 GeV/c2, the dark matter particle mass being anywhere below m(T'). The data are consistent with standard model expectations, and we set 95% confidence level limits on the generic production of T'T' → tt + X + X. For the dark matter model we exclude T' at 95% confidence level up to m(T') = 360 GeV/c2 for m(X) ≤ 100 GeV/c2.

Search for new physics in high pT like-sign dilepton events at CDF II.

We present a search for new physics in events with two high pT leptons of the same electric charge, using data with an integrated luminosity of 6.1 fb(-1). The observed data are consistent with standard model predictions. We set 95% C.L. lower limits on the mass of doubly charged scalars decaying to like-sign dileptons, m(H±±) > 190-245 GeV/c(2), assuming 100% BR to ee, µµ or eµ.

Measurement of polarization and search for CP violation in B(s)0→φφ decays.

We present the first measurement of polarization and CP-violating asymmetries in a B(s)(0) decay into two light vector mesons, B(s)(0)→φφ, and an improved determination of its branching ratio using 295 decays reconstructed in a data sample corresponding to 2.9 fb(-1) of integrated luminosity collected by the CDF experiment at the Fermilab Tevatron collider. The fraction of longitudinal polarization is determined to be f(L)=0.348±0.041(stat)±0.021(syst), and the branching ratio B(B(s)(0)→φφ)=[2.32±0.18(stat)±0.82(syst)]×10(-5). Asymmetries of decay angle distributions sensitive to CP violation are measured to be A(u)=-0.007±0.064(stat)±0.018(syst) and A(v)=-0.120±0.064(stat)±0.016(syst).

Search for a heavy toplike quark in pp collisions at √s=1.96 TeV.

We present the results of a search for pair production of a heavy toplike (t') quark decaying to Wq final states using data corresponding to an integrated luminosity of 5.6 fb(-1) collected by the CDF II detector in pp collisions at √s=1.96 TeV. We perform parallel searches for t'→Wb and t'→Wq (where q is a generic down-type quark) in events containing a lepton and four or more jets. By performing a fit to the two-dimensional distribution of total transverse energy versus reconstructed t' quark mass, we set upper limits on the t't' production cross section and exclude a standard model fourth-generation t' quark decaying to Wb (Wq) with mass below 358 (340) GeV/c(2) at 95% C.L.

Measurement of the B(s)0 lifetime in fully and partially reconstructed B(s)0→D(s)(-)(ϕπ(-))X decays in p¯p collisions at √s=1.96 TeV.

We present a measurement of the B(s)(0) lifetime in fully and partially reconstructed B(s)(0)→D(s)(-)(ϕπ(-))X decays in 1.3 fb(-1) collected in pp ¯ collisions at √s=1.96 TeV by the CDF II detector at the Fermilab Tevatron. We measure τ(B(s)(0))=1.518±0.041(stat)±0.027(syst) ps. The ratio of this result and the world average B(0) lifetime yields τ(B(s)(0))/τ(B(0))=0.99±0.03, which is in agreement with recent theoretical predictions.

Search for B(s)(0) → µ+ µ- and B(0) → µ+ µ- decays with CDF II.

A search has been performed for B(s)(0) → µ+ µ- and B(0) → µ+ µ- decays using 7 fb(-1) of integrated luminosity collected by the CDF II detector at the Fermilab Tevatron collider. The observed number of B(0) candidates is consistent with background-only expectations and yields an upper limit on the branching fraction of B(B(0) → µ+ µ-) < 6.0 × 10(-9) at 95% confidence level. We observe an excess of B(s)(0) candidates. The probability that the background processes alone could produce such an excess or larger is 0.27%. The probability that the combination of background and the expected standard model rate of B(s)(0) → µ+ µ- could produce such an excess or larger is 1.9%. These data are used to determine B(B(s)(0)→ µ+ µ-) = (1.8(-0.9) (+1.1)) × 10(-8) and provide an upper limit of B(B(s)(0) → µ+ µ-) < 4.0 × 10(-8) at 95% confidence level.

Search for New T' particles in final states with large jet multiplicities and missing transverse energy in p p collisions at sqrt[s] = 1.96 TeV.

We present a search for a new particle T' decaying to a top quark via T' → t + X, where X goes undetected. We use a data sample corresponding to 5.7 fb(-1) of integrated luminosity of p p collisions with sqrt[s] = 1.96 TeV, collected at Fermilab Tevatron by the CDF II detector. Our search for pair production of T' is focused on the hadronic decay channel, pp → T'T' → tt + XX → bqq b qq + XX. We interpret our results in terms of a model where T' is an exotic fourth generation quark and X is a dark matter particle. The data are consistent with standard model expectations. We set a limit on the generic production of T'T' → tt + XX, excluding the fourth generation exotic quarks T' at 95% confidence level up to m(T') = 400 GeV/c(2) for m(X) ≤ 70 GeV/c(2).