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1.

Cytomegalovirus subverts macrophage identity.

Baasch, Sebastian; Giansanti, Piero; Kolter, Julia; Riedl, André; Forde, Aaron James; Runge, Solveig; Zenke, Simon; Elling, Roland; Halenius, Anne; Brabletz, Simone; Hengel, Hartmut; Kuster, Bernhard; Brabletz, Thomas; Cicin-Sain, Luka; Arens, Ramon; Vlachos, Andreas; Rohr, Jan Christopher; Stemmler, Marc Philippe; Kopf, Manfred; Ruzsics, Zsolt; Henneke, Philipp.

Cell; 184(14): 3774-3793.e25, 2021 07 08.

Artículo en Inglés | MEDLINE | ID: mdl-34115982

2.

Tissue-resident memory CD8⁺ T cells shape local and systemic secondary T cell responses.

Behr, Felix M; Parga-Vidal, Loreto; Kragten, Natasja A M; van Dam, Teunis J P; Wesselink, Thomas H; Sheridan, Brian S; Arens, Ramon; van Lier, Rene A W; Stark, Regina; van Gisbergen, Klaas P J M.

Nat Immunol; 21(9): 1070-1081, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32661361

3.

'Reverse evolution' in T cell biology.

Redeker, Anke; Arens, Ramon.

Nat Immunol; 21(4): 360-362, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32205884

4.

In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity.

Halle, Stephan; Keyser, Kirsten Anja; Stahl, Felix Rolf; Busche, Andreas; Marquardt, Anja; Zheng, Xiang; Galla, Melanie; Heissmeyer, Vigo; Heller, Katrin; Boelter, Jasmin; Wagner, Karen; Bischoff, Yvonne; Martens, Rieke; Braun, Asolina; Werth, Kathrin; Uvarovskii, Alexey; Kempf, Harald; Meyer-Hermann, Michael; Arens, Ramon; Kremer, Melanie; Sutter, Gerd; Messerle, Martin; Förster, Reinhold.

Immunity; 44(2): 233-45, 2016 Feb 16.

Artículo en Inglés | MEDLINE | ID: mdl-26872694

5.

CRISPR Activation Screening Identifies VGLL3-TEAD1-RUNX1/3 as a Transcriptional Complex for PD-L1 Expression.

Wijdeven, Ruud H; Cabukusta, Birol; Behr, Felix M; Qiu, Xueer; Amiri, Deeba; Borras, Daniel M; Arens, Ramon; Liang, Yun; Neefjes, Jacques.

J Immunol; 209(5): 907-915, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-35922063

6.

Enhanced HPV16 E6/E7⁺ tumor eradication via induction of tumor-specific T cells by therapeutic vaccination with virosomes presenting synthetic long peptides.

Stegmann, Toon; Wiekmeijer, Anna-Sophia; Kwappenberg, Kitty; van Duikeren, Suzanne; Bhoelan, Farien; Bemelman, Denzel; Beenakker, Thomas J M; Krebber, Willem-Jan; Arens, Ramon; Melief, Cornelis J M.

Cancer Immunol Immunother; 72(8): 2851-2864, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37222770

7.

Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells.

Feau, Sonia; Arens, Ramon; Togher, Susan; Schoenberger, Stephen P.

Nat Immunol; 12(9): 908-13, 2011 Jul 31.

Artículo en Inglés | MEDLINE | ID: mdl-21804558

8.

Mucosal memory CD8âº T cells are selected in the periphery by an MHC class I molecule.

Huang, Yujun; Park, Yunji; Wang-Zhu, Yiran; Larange, Alexandre; Arens, Ramon; Bernardo, Iván; Olivares-Villagómez, Danyvid; Herndler-Brandstetter, Dietmar; Abraham, Ninan; Grubeck-Loebenstein, Beatrix; Schoenberger, Stephen P; Van Kaer, Luc; Kronenberg, Mitchell; Teitell, Michael A; Cheroutre, Hilde.

Nat Immunol; 12(11): 1086-95, 2011 Oct 02.

Artículo en Inglés | MEDLINE | ID: mdl-21964609

9.

Genetic Screening for Novel Regulators of Immune Checkpoint Molecules.

Arens, Ramon; Scheeren, Ferenc A.

Trends Immunol; 41(8): 692-705, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32605801

10.

Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.

Aslam, Muhammad Assad; Alemdehy, Mir Farshid; Kwesi-Maliepaard, Eliza Mari; Muhaimin, Fitriari Izzatunnisa; Caganova, Marieta; Pardieck, Iris N; van den Brand, Teun; van Welsem, Tibor; de Rink, Iris; Song, Ji-Ying; de Wit, Elzo; Arens, Ramon; Jacobs, Heinz; van Leeuwen, Fred.

EMBO Rep; 22(2): e51184, 2021 02 03.

Artículo en Inglés | MEDLINE | ID: mdl-33410591

11.

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.

Qiao, Xiaohang; van der Zanden, Sabina Y; Wander, Dennis P A; Borràs, Daniel M; Song, Ji-Ying; Li, Xiaoyang; van Duikeren, Suzanne; van Gils, Noortje; Rutten, Arjo; van Herwaarden, Tessa; van Tellingen, Olaf; Giacomelli, Elisa; Bellin, Milena; Orlova, Valeria; Tertoolen, Leon G J; Gerhardt, Sophie; Akkermans, Jimmy J; Bakker, Jeroen M; Zuur, Charlotte L; Pang, Baoxu; Smits, Anke M; Mummery, Christine L; Smit, Linda; Arens, Ramon; Li, Junmin; Overkleeft, Hermen S; Neefjes, Jacques.

Proc Natl Acad Sci U S A; 117(26): 15182-15192, 2020 06 30.

Artículo en Inglés | MEDLINE | ID: mdl-32554494

12.

Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model.

Kumar, Sumit; Schoonderwoerd, Mark J A; Kroonen, Jessie S; de Graaf, Ilona J; Sluijter, Marjolein; Ruano, Dina; González-Prieto, Román; Verlaan-de Vries, Matty; Rip, Jasper; Arens, Ramon; de Miranda, Noel F C C; Hawinkels, Lukas J A C; van Hall, Thorbald; Vertegaal, Alfred C O.

Gut; 71(11): 2266-2283, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-35074907

13.

The curious case of IL-33 in homeostasis and infection.

Nadafi, Reza; Arens, Ramon.

Eur J Immunol; 51(1): 60-63, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33222176

14.

Interleukin-6-mediated resistance to immunotherapy is linked to impaired myeloid cell function.

Beyranvand Nejad, Elham; Labrie, Camilla; van der Sluis, Tetje C; van Duikeren, Suzanne; Franken, Kees L M C; Roosenhoff, Rueshandra; Arens, Ramon; van Hall, Thorbald; van der Burg, Sjoerd H.

Int J Cancer; 148(1): 211-225, 2021 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-32875568

15.

Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets.

Van Belle, Tom L; Nierkens, Stefan; Arens, Ramon; von Herrath, Matthias G.

Immunity; 36(6): 1060-72, 2012 Jun 29.

Artículo en Inglés | MEDLINE | ID: mdl-22579473

16.

Peripheral and systemic antigens elicit an expandable pool of resident memory CD8⁺ T cells in the bone marrow.

Pascutti, Maria Fernanda; Geerman, Sulima; Collins, Nicholas; Brasser, Giso; Nota, Benjamin; Stark, Regina; Behr, Felix; Oja, Anna; Slot, Edith; Panagioti, Eleni; Prier, Julia E; Hickson, Sarah; Wolkers, Monika C; Heemskerk, Mirjam H M; Hombrink, Pleun; Arens, Ramon; Mackay, Laura K; van Gisbergen, Klaas P J M; Nolte, Martijn A.

Eur J Immunol; 49(6): 853-872, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30891737

17.

The hallmarks of CMV-specific CD8 T-cell differentiation.

van den Berg, Sara P H; Pardieck, Iris N; Lanfermeijer, Josien; Sauce, Delphine; Klenerman, Paul; van Baarle, Debbie; Arens, Ramon.

Med Microbiol Immunol; 208(3-4): 365-373, 2019 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-30989333

18.

Human plasmacytoid dendritic cells acquire phagocytic capacity by TLR9 ligation in the presence of soluble factors produced by renal epithelial cells.

Ruben, Jurjen M; García-Romo, Gina Stella; Breman, Eytan; van der Kooij, Sandra; Redeker, Anke; Arens, Ramon; van Kooten, Cees.

Kidney Int; 93(2): 355-364, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29061332

19.

The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection.

Panagioti, Eleni; Redeker, Anke; van Duikeren, Suzanne; Franken, Kees Lmc; Drijfhout, Jan Wouter; van der Burg, Sjoerd H; Arens, Ramon.

PLoS Pathog; 12(9): e1005895, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27637068

20.

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors.

Dekhtiarenko, Iryna; Ratts, Robert B; Blatnik, Renata; Lee, Lian N; Fischer, Sonja; Borkner, Lisa; Oduro, Jennifer D; Marandu, Thomas F; Hoppe, Stephanie; Ruzsics, Zsolt; Sonnemann, Julia K; Mansouri, Mandana; Meyer, Christine; Lemmermann, Niels A W; Holtappels, Rafaela; Arens, Ramon; Klenerman, Paul; Früh, Klaus; Reddehase, Matthias J; Riemer, Angelika B; Cicin-Sain, Luka.

PLoS Pathog; 12(12): e1006072, 2016 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-27977791

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