Detalles de la búsqueda
1.
RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule.
Cell;
157(2): 313-328, 2014 04 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24656405
2.
Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule.
Cell;
170(2): 407, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28709005
3.
Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.
J Neurosci;
43(13): 2222-2241, 2023 03 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-36868853
4.
Monitoring drug-target interactions through target engagement-mediated amplification on arrays and in situ.
Nucleic Acids Res;
50(22): e129, 2022 12 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36189884
5.
Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity.
Br J Clin Pharmacol;
88(9): 4121-4133, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35404513
6.
High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.
Pharm Res;
39(7): 1599-1613, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35089508
7.
Correlations between 4ß-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range.
Eur J Clin Pharmacol;
78(8): 1289-1299, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35648149
8.
Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.
Int J Mol Sci;
23(13)2022 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35806468
9.
Hepatocyte size fractionation allows dissection of human liver zonation.
J Cell Physiol;
236(8): 5885-5894, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33452735
10.
Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes.
Mol Pharm;
18(4): 1792-1805, 2021 04 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33739838
11.
A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity.
Drug Metab Dispos;
48(1): 8-17, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31685482
12.
Cell-type-resolved proteomic analysis of the human liver.
Liver Int;
40(7): 1770-1780, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32243721
13.
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.
Proc Natl Acad Sci U S A;
114(30): E6231-E6239, 2017 07 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-28701380
14.
Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking.
J Proteome Res;
18(1): 217-224, 2019 01 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30336047
15.
Image-Based Quantification of Cell Debris as a Measure of Apoptosis.
Anal Chem;
91(9): 5548-5552, 2019 05 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31001971
16.
A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu,cell).
Pharm Res;
36(12): 178, 2019 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31701258
17.
A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes.
Arch Toxicol;
93(3): 819-829, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30560367
18.
Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates.
Drug Metab Dispos;
46(4): 387-396, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29343608
19.
Structural and conformational determinants of macrocycle cell permeability.
Nat Chem Biol;
12(12): 1065-1074, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27748751
20.
Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids.
Mol Pharm;
15(6): 2224-2233, 2018 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29709195