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1.
Int J Neurosci ; 132(7): 735-743, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33866943

RESUMEN

AIM: Brain arteriovenous malformations (AVMs) are congenital anomalies that present as intracranial hemorrhage or epilepsy. AVMs often remain clinically silent for extended periods. Although AVM treatment methods are controversial, three treatment strategies are usually combined or applied alone: surgical removal, embolization and stereotactic radiosurgery. We compared clinical and radiological outcomes in intracranial AVM patients treated via surgical resection with and without prior embolization. MATERIALS AND METHODS: Patients who did (30 patients) and did not (30 patients) undergo endovascular embolization before surgical resection at the Izmir Katip Çelebi University Atatürk Training and Research Hospital Neurosurgery Clinic from 2011 to 2019 were included in this retrospective, cohort study. Symptoms at diagnosis, comorbidities and clinical (AVM and Spetzler-Martin grade) and morphological characteristics were assessed. RESULTS: A mean one-year follow-up assessed outcomes using the modified Rankin score, and imaging studies assessed AVM obliteration post-procedure. Mean operation times for surgical resection with and without embolization were 166.50 ± 32.02 and 204.47 ± 26.66 min, respectively. Mean patient hospitalization periods for surgical resection with and without embolization were 8.43 ± 3.60 and 12.00 ± 5.51 days, respectively. CONCLUSION: Among patients who underwent surgical resection, significant operation time and hospitalization time differences were observed in favor of patients who underwent embolization, indicating that preoperative embolization is a safe and beneficial method for treating ruptured and non-ruptured AVMs.


Asunto(s)
Embolización Terapéutica , Malformaciones Arteriovenosas Intracraneales , Radiocirugia , Estudios de Cohortes , Embolización Terapéutica/métodos , Estudios de Seguimiento , Humanos , Malformaciones Arteriovenosas Intracraneales/diagnóstico por imagen , Malformaciones Arteriovenosas Intracraneales/cirugía , Radiocirugia/métodos , Estudios Retrospectivos , Resultado del Tratamiento
2.
Child Care Health Dev ; 48(3): 465-473, 2022 05.
Artículo en Inglés | MEDLINE | ID: mdl-34904251

RESUMEN

BACKGROUND: This study aims to translate the caregiver difficulties scale (CDS) into Turkish language and to reveal its reliability and validity in Turkish informal family caregivers of children with cerebral palsy (CP). METHODS: This study included 130 participants (39.9 ± 7.8 years; range 24-58 years; 106 females and 24 males). Demographic properties of participants, relationship with the care recipient, income, caregiving time, CP type and diseases of the child (e.g., epilepsy, hydrocephalus and congenital heart disease) and the caregiver were recorded. The CDS, caregiver well-being scale (CWBS), World Health Organization Quality of Life (WHOQOL-BREF) and Beck depression inventory (BDI) were used for data collection. The internal consistency of the CDS was assessed using the calculation of Cronbach's alpha coefficient. A test-retest interval of 2 weeks was used to assess the reliability. The intercorrelation of variables was evaluated using the Spearman correlation coefficient. The receiver operating characteristic (ROC) analysis was performed to find the predictive power of CDS scores for depression. RESULTS: A total of 130 family caregivers of children with CP completed the test/retest procedures. The Cronbach alpha coefficients were found as 0.878 for the test and 0.852 for the retest. Intraclass correlation coefficient (ICC) value was found between 0.83 and 0.90 for test-retest reliability of the CDS. In addition, the CDS showed a significantly strong correlation with CWBS-activities of living subscale and WHOQOL-BREF psychological, physical and environment domains, as well as a significantly moderate correlation with CWBS basic needs subscale, BDI and WHOQOL-BREF general health and social domains. CDS scores that are >46 resulted in a sensitivity of 81.48% and a specificity of 73.79% for moderate-severe depression. CONCLUSION: The Turkish version of the CDS is a valid and reliable measure for caregiver burden of family caregivers of children with CP.


Asunto(s)
Cuidadores , Parálisis Cerebral , Carga del Cuidador , Cuidadores/psicología , Niño , Femenino , Humanos , Lenguaje , Masculino , Calidad de Vida , Reproducibilidad de los Resultados , Encuestas y Cuestionarios
3.
Br J Neurosurg ; 35(2): 186-190, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-32672074

RESUMEN

Background: As an advanced imaging technique for the human brain, the importance of magnetic resonance imaging technique (MRI) is indisputable. The study aims to contribute to the literature by imaging post-mortem human brain hemispheres fixed with the Klinger method through the a 3.0 Tesla MRI Scanner and by defining the supratentorial major white matter tracts and central core anatomical structures.Methods: In our study, 10 post-mortem human brain hemisphere specimens were placed in 10% formalin solution for at least two months according to the Klingler method. The images were obtained using a 3.0 Tesla MRI Scanner. Anatomical structures were described on the T1-T2 axial, coronal, and sagittal MRI sections and compared with control images obtained from healthy humans.Results: Our examination revealed major association fibers, the basal cores and nuclei were denser, and the connections between them were clearly visible. The basal nuclei particularly were visualized more clearly compared with the normal MRI examinations. The claustrum, putamen, lateral and medial part of globus pallidus, and the caudolenticular bridges of the caudate nucleus could be clearly distinguished. The optic radiation line toward the occipital area as well as the forceps major and minor were distinct in the axial sections. Meanwhile, the imaging emphasized the importance of temporal stem, and the fibers it contained were clearly observed in the coronal sections.Conclusion: The use of hemispheres fixed using the Klinger method in post-mortem MRI examinations on brain hemispheres showed a clear separation of white matter fibers and nuclear structures.


Asunto(s)
Cerebro , Sustancia Blanca , Autopsia , Encéfalo/diagnóstico por imagen , Humanos , Imagen por Resonancia Magnética , Sustancia Blanca/diagnóstico por imagen
4.
J Org Chem ; 84(24): 15972-15977, 2019 12 20.
Artículo en Inglés | MEDLINE | ID: mdl-31769288

RESUMEN

The fluorescence emission of the parent 2-aminobenzimidazole (ABZ, 1), the mono- and disubstituted derivatives (2, 3), 2-aminonaphthoimidazole (4), and 4-amino dinaphthodiazepine 5 (λem = 315-400 nm) is strongly quenched in the presence of aqueous hydrogen peroxide. The quenching process is dual: for diazepine 5, quenching is dynamic at lower H2O2 concentrations with linear reduction of the fluorescence lifetime from 4.3 to 2.6 ns. At higher H2O2 concentrations, a second species appears in the absorption and emission spectra with fluorescence lifetimes of 1.3 ns, indicating the formation of a new (ground-state) hydrogen-bonded ABZ-H2O2 complex (static quenching). Sensors 1 and 2 show also dual quenching that fits with a static 1:1 and 1:2 model with K1:1 = 8(11) M-1 and K1:2 = 21(147) M-1 for 1(2). The formation of a 1:2 complex (1:(H2O2)2) is also supported by density functional theory (DFT) calculations and spectra simulations.

5.
J Craniofac Surg ; 30(3): 818-822, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31048611

RESUMEN

Basilar invagination, Platibasi, increased tentorium angle, and posterior fossa hypoplasia are the anomalies associated with Chiari malformation. When Chiari is symptomatic; tonsillary ectopenia appears to be a definitive criterion for diagnosis and treatment, the detection of additional anomaly may alter the surgical outcome. The aim of this study is to investigate the relationship between tonsillar ectopia and other anomalies.The authors retrospectively reviewed 31 cases which had Chiari Malformation at our Hospital. There were 8 men (25.8%) and 23 female (74.2%). Average age of the samples is 37.93 ±â€Š12.93 years. Seventeen patients (54.8%) had tonsillar ectopia 0 to 5 mm, 14 patients had tonsillar ectopia over 5 mm. Seven patients had syrinx (22.6%), 2 patients had mild hydrocephalus (6.5%). Six patients had surgery for the treatment. The mean length of the clivus was 39.3 mm, supraoksiput length was 40.4 mm, cerebellar hemisphere length was 61.08 mm, Mc Rae line was 33.14 mm, Twinning Line was 79.4mm, and Tentorium-Twinning line angle was 40.35°. There was no significant difference between Tonsillar ectopia, syrinks, and hydrocephalus. Basilar invagination had relationship between platibasi (6 patients had platibasi according to 2 mm criteria, 2 patients had platibasi according to 5 mm criteria (P < 0.05). Patients with syrinx had relationship between Chamberlain line (P < 0.05).In the authors' study, although there was no statistically significant difference between the tonsillary ectopia and the criteria of these anomalies, the relationship between basilar invagination and platibasi was significant.


Asunto(s)
Malformación de Arnold-Chiari/diagnóstico por imagen , Cefalometría/métodos , Imagen por Resonancia Magnética/métodos , Base del Cráneo/diagnóstico por imagen , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
6.
Int Braz J Urol ; 45(1): 179-182, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30648825

RESUMEN

INTRODUCTION: Double-J stent insertion during laparoscopic pyeloplasty is a difficult and time-consuming process and several techniques were defined to perform a double-J stent with an antegrade approach. In this study we present the technique (PICA) of antegrade double-J placement during laparoscopic pyeloplasty by using 14 gauge intravenous cannula. Surgical technique: After we complete the suturing of the posterior wall of the anastomosis during laparoscopic pyeloplasty, we first puncture the abdominal wall with a 14-gauge "intravenous cannula" from a location that provides most suitable angle for inserting the double-J stent into the ureter. We remove the metal needle of the cannula, and the sheath which has an inner diameter of 5.2F remains over the abdominal wall. The double J stent is then advanced from inside the cannula sheath to the intraperitoneal area; under laparoscopic imaging the stent is gently grasped at its distal end using an atraumatic laparoscopic forceps to insert it into the ureter. The stent is then pulled down to its proximal end, and after the guidewire is removed, the proximal end of the double-J stent is placed inside the renal pelvis with an atraumatic forceps. With this technique we can apply the double-J stent in just one step. Additionaly we can use a 14-gauge IV cannula sheath as a trocar when needed during laparoscopic pyeloplasty to retract an organ or reveal an anastomosis line. COMMENTS: Our new technique of antegrade double-J placement during laparoscopic pyeloplasty by 14 gauge intravenous cannula sheath, is very easy and quick to perform.


Asunto(s)
Cánula , Laparoscopía/métodos , Stents , Procedimientos Quirúrgicos Urológicos/métodos , Humanos , Procedimientos Quirúrgicos Urológicos/instrumentación
7.
Turk J Med Sci ; 49(3): 922-927, 2019 06 18.
Artículo en Inglés | MEDLINE | ID: mdl-31121999

RESUMEN

Background/aim: Application fields of bone tissue engineering studies continue to expand. New biocompatible materials aimed to improve bone repairment and regeneration of implants are being discovered everyday by scientists, engineers, and surgeons. Our objective in this study is to combine polylactic acid which is a polymer with hydroxyapatite in the repairment of bone defects considering the increased need by medical application fields. Materials and methods: After 750 g of PLA with a diameter of 2.85 mm was granulated into minimum particles, these particles were homogenously mixed with hydroxyapatite prepared in laboratory environment. Using this mixture, HA-PLA filament with a diameter of 2.85 mm was prepared in the extrusion device in Kütahya Medical Sciences University Innovative Technology Laboratory. The temperature was 250 °C and the gearmotor speed was 9 rpm during extrusion. X-ray diffraction (XRD) analysis was made for crystal phase analyses of the produced hydroxyapatite powder, to determine the produced main phase and examine whether a minor phase occurred. Vickers microhardness test was applied on both samples to measure the endurance levels of the samples prepared with HA-PLA filament. A loading force of 10 kg was applied on the samples for 10 s. Results: Hydroxyapatite peaks in XRD spectrum of the sample presented in figures are concordant with Joint Committee on Powder Diffraction Standards, JCPDS - File Card No. 01-075-9526 and no significant minor phase was observed. For both samples, hardness value was observed to increase between 3 and 5 mm. Conclusion: Surfacing hydroxyapatite on metallic materials is possible. By similar logic, to increase durability with low cost, characteristics of biomaterials can be improved with combinations such as hydroxyapatite PLA. Thus, we found that while these materials have usage limitations due to present disadvantages when used alone, it is possible to increase their efficiency and availability through different combinations.


Asunto(s)
Sustitutos de Huesos/química , Durapatita/química , Poliésteres/química , Impresión Tridimensional , Ingeniería de Tejidos/instrumentación , Ensayo de Materiales , Difracción de Rayos X
8.
J Med Genet ; 51(4): 239-44, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24431330

RESUMEN

BACKGROUND: Azoospermia is the absence of a measurable level of spermatozoa in the semen. It affects approximately 1% of all men, and the genetic basis of the majority of idiopathic cases is unknown. We investigated two unrelated consanguineous families with idiopathic azoospermia. In family 1, there were three azoospermic brothers and one oligozoospermic brother; and in family 2, there were three azoospermic brothers. Testis biopsy in the brothers in family 2 had led to the diagnosis of maturation arrest in the spermatid stage. METHODS: Candidate disease loci were found via linkage mapping using data from single nucleotide polymorphism genome scans. Exome sequencing was applied to find the variants at the loci. RESULTS: We identified two candidate loci in each family and homozygous truncating mutations p.R611X in TAF4B in family 1 and p.K507Sfs*3 in ZMYND15 in family 2. We did not detect any mutations in these genes in a cohort of 45 azoospermic and 15 oligozoospermic men. Expression studies for ZMYND15 showed that the highest expression was in the testis. CONCLUSIONS: Both genes are known to have roles in spermatogenesis in mice but neither has been studied in humans. To our knowledge, they are the first genes identified for recessive idiopathic spermatogenic failure in men. Assuming that recessive genes for isolated azoospermia are as numerous in men as in mice, each gene is possibly responsible for only a small fraction of all cases.


Asunto(s)
Azoospermia/genética , Proteínas Portadoras/genética , Genes Recesivos/genética , Mutación/genética , Factores Asociados con la Proteína de Unión a TATA/genética , Factor de Transcripción TFIID/genética , Animales , Familia , Femenino , Sitios Genéticos/genética , Haplotipos/genética , Homocigoto , Humanos , Infertilidad Masculina/genética , Masculino , Ratones , Linaje
9.
J Sex Med ; 11(7): 1816-22, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24612455

RESUMEN

INTRODUCTION: The pathophysiology of erectile dysfunction (ED) may be vasculogenic, hormonal, anatomical, neurogenic, drug-induced and/or psychogenic in origin. Neuropathic pain (NP) may facilitate ED, because it is frequently associated with anxiety, depression, and its drug, pregabalin, may also contribute ED. AIM: The objective of this study was to determine whether pregabalin treatment for patients with neuropathic pain promotes erectile dysfunction. METHODS: The study sample consisted of a total of 102 male subjects that were subdivided into three groups. Group 1 patients (n = 31) had a pre-existing diagnosis of NP and was treated with 300 mg/day of pregabalin for at least 3 months. Group 2 patients (n = 34) were diagnosed with NP for at least 3 months; however, neither were they treated with pregabalin nor did they received physical therapy throughout the study. Lastly, healthy age-matched control subjects comprised group 3 (n = 37). MAIN OUTCOME MEASURES: Patients in all groups completed the International Index for Erectile Function (IIEF) questionnaire. RESULTS: Mean age and mean body mass index did not differ significantly between each of the three groups. The cause of NP and the mean duration of having a diagnosis of NP did not differ significantly in groups 1 and 2. However, IIEF scores were significantly lower for group 1 when compared to group 2 in terms of erectile function, orgasmic function, overall satisfaction and total score. Yet groups 1 and 2 did not diverge significantly in the intercourse satisfaction and sexual desire scores. Overall IIEF scores for group 3 were significantly higher than those of group 2 except for mean erectile function scores. CONCLUSION: Taking pregabalin for the treatment of neuropathic pain poses an increased risk for developing ED in male patients. Thus, clinicians prescribing pregabalin to patients diagnosed with neuropathic pain should assess for ED before and during treatment with this medication.


Asunto(s)
Analgésicos/efectos adversos , Disfunción Eréctil/inducido químicamente , Neuralgia/tratamiento farmacológico , Ácido gamma-Aminobutírico/análogos & derivados , Adulto , Coito/fisiología , Depresión/etiología , Disfunción Eréctil/tratamiento farmacológico , Humanos , Libido/efectos de los fármacos , Masculino , Satisfacción del Paciente , Pregabalina , Encuestas y Cuestionarios , Resultado del Tratamiento , Ácido gamma-Aminobutírico/efectos adversos
10.
Arch Ital Urol Androl ; 86(4): 300-3, 2014 Dec 30.
Artículo en Inglés | MEDLINE | ID: mdl-25641458

RESUMEN

In recent years, day by day, robotic surgery applications have increase their role in our medical life. In this article, we reported the discovery of the first primitive robotic applications as automatic machines for the sensitive calculation of liquids such as blood in the literature. Al-Jazari who wrote the book "Elcâmi 'Beyne'l - 'ilm ve'l - 'amel en-nâfi 'fi es-sinaâ 'ti'l - hiyel", lived in Anatolian territory between 1136 and 1206. In this book that was written in the twelfth century, Al-Jazari described nearly fifty graphics of robotic machines and six of them that were designed for medical purposes. We found that some of the robots mentioned in this book are related to medical applications. This book reviews approximately 50 devices, including water clocks, candle clocks, ewers, various automata used for amusement in drink assemblies, automata used for ablution, blood collection tanks, fountains, music devices, devices for water lifting, locks, a protractor, a boat-shaped water clock, and the gate of Diyarbakir City in south-east of Turkey, actually in northern Mesopotamia. We found that automata used for ablution and blood collection tanks were related with medical applications; therefore, we will describe these robots.


Asunto(s)
Robótica/historia , Asia , Diseño de Equipo , Historia Medieval , Robótica/instrumentación
11.
Turk Neurosurg ; 34(3): 429-434, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38650556

RESUMEN

AIM: To evaluate outcome of patients with hemifacial spasm surgically treated by microvascular decompression without the use of neuromonitoring and fix retraction. MATERIAL AND METHODS: Of the 78 patients with hemifacial spasm operated by the senior author of this study between 2016 and 2020, 60 patients who were followed up were included and retrospectively investigated. The female:male ratio was 32:28, and the mean age was 42.5 ± 11.5 years (range 23?71 years). All the patients were operated via the lateral retrosigmoid suboccipital infrafloccular approach, and no permanent retractor was employed during the procedures. Additionally, intraoperative neuromonitoring was not performed for any of the patients. RESULTS: Single vessel compression was observed in 77% of the patients, whereas 16% and 6% experienced compression in two and three vessels, respectively. Immediate recovery was achieved in 70% of the patients. Half of the remaining 30% fully recovered within 6 months?2 years. Furthermore, the complaints of 5% of the patients were alleviated, whereas no improvement was observed in 10% of the patients. One patient developed a recurrence. CONCLUSION: Microvascular decompression is a highly effective method for the treatment of hemifacial spasm. In this study, we did not resort to intraoperative neuromonitoring and observed that our postoperative complication rates were consistent with the existing literature.


Asunto(s)
Espasmo Hemifacial , Cirugía para Descompresión Microvascular , Humanos , Espasmo Hemifacial/cirugía , Cirugía para Descompresión Microvascular/métodos , Femenino , Masculino , Adulto , Persona de Mediana Edad , Anciano , Resultado del Tratamiento , Estudios Retrospectivos , Adulto Joven
12.
Turk Neurosurg ; 34(2): 250-255, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38497177

RESUMEN

AIM: To compare the clinical and radiological outcomes of unilateral percutaneous kyphoplasty (PKP) surgeries performed using 3D printing technology in patients with osteoporotic compression fractures to conventional unilateral PKP surgeries. MATERIAL AND METHODS: Patients with acute painful single-level osteoporotic vertebral compression fracture (OVCF) who need surgical treatment were divided into two groups: group A (patients who had 3D template-guided PKP) and group B (patients who conventional PKP). To compare the two surgical procedures, Total Absorbed Radiation Dose (TARD), pre- and postoperative visual analog scale (VAS) scores, and Total Surgery Time (TST) were calculated and compared between groups in both surgical groups. RESULTS: A total of 44 patients with single-level OVCF who were experiencing acute pain were successfully operated on, with 22 patients in each group. TARD (2.6 ± 0.4 mGy vs. 6.1 ± 1.9 mGy, p < 0.05) and TST (12.4 ± 2.6 min vs. 20.2 ± 3.2 min, p < 0.05) differed significantly different between groups A and B. There was no statistically significant difference between the patient groups in preoperative and postoperative VAS values (p > 0.05). Cement leakage was lower in group A (3/22, 13.6%) than in group B (6/22, 27.3%) (p > 0.05). There were no neurological complications or infections in either group. CONCLUSION: When compared to the conventional procedure, the unilateral percutaneous kyphoplasty method was supported by a 3D printing guide template. By reducing operative time and radiation exposure, tt has resulted in a more effective surgical procedure for patients and a safer surgical procedure for surgeons and anaesthesiologists.


Asunto(s)
Fracturas por Compresión , Cifoplastia , Fracturas Osteoporóticas , Fracturas de la Columna Vertebral , Vertebroplastia , Humanos , Cifoplastia/efectos adversos , Fracturas por Compresión/diagnóstico por imagen , Fracturas por Compresión/cirugía , Fracturas de la Columna Vertebral/diagnóstico por imagen , Fracturas de la Columna Vertebral/cirugía , Columna Vertebral , Vertebroplastia/métodos , Fracturas Osteoporóticas/diagnóstico por imagen , Fracturas Osteoporóticas/cirugía
13.
J Mater Chem C Mater ; 12(24): 8759-8776, 2024 Jun 20.
Artículo en Inglés | MEDLINE | ID: mdl-38912177

RESUMEN

Metal-organic frameworks (MOFs) have gathered significant interest due to their tunable porosity leading to diverse potential applications. In this study, we investigate the incorporation of the fluorosolvatochromic dye 2-butyl-5,6-dimethoxyisoindoline-1,3-dione ([double bond, length as m-dash]Phth) into various MOF structures as a means to assess the polarity of these porous materials. As a purely inorganic compound, zeolite Y was tested for comparison. The fluorosolvatochromic behavior of Phth, which manifests as changes in its emission spectra in response to solvent polarity, provides a sensitive probe for characterizing the local environment within the MOF pores. Through systematic variation of the MOF frameworks, we demonstrate the feasibility of using (fluoro-)solvatochromic dyes as probes for assessing the polarity gradients within MOF structures. Additionally, the fluorosolvatochromic response was studied as a function of loading amount. Our findings not only offer insights into the interplay between MOF architecture and guest molecule interactions but also present a promising approach for the rational design and classification of porous materials based on their polarity properties.

14.
J Urol ; 189(3): 1054-60, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23022000

RESUMEN

PURPOSE: We conducted a multicenter pediatric study of ureteral stents unintentionally left in situ. MATERIALS AND METHODS: A total of 22 patients with encrusted Double-J® ureteral stents unintentionally left in situ were treated at 4 centers between January 2007 and March 2012. Stone burdens were estimated using plain radiography and computerized tomography. Treatment decision was made based on clinical and radiological findings or stone burden. RESULTS: Nine girls and 13 boys with a mean age of 9.5 years (range 2 to 16) were analyzed. Mean indwelling time of ureteral stent was 21.7 months (range 6 to 60). Stents were inserted for the indication of urolithiasis (17 patients) and reconstructive urological intervention (5). In 2 patients stents had been placed bilaterally. Mean stent stone burden was 184 mm(2) on plain radiography and 247 mm(2) on computerized tomography, a difference that was statistically significant (p = 0.002). Shock wave lithotripsy was done in 6 cases. Endoscopic procedures were performed in all patients, including ureteroscopy in 8, simple stent removal in 7, endoscopic cystolithotripsy in 6, percutaneous nephrolithotomy in 5, retrograde intrarenal surgery in 3 and percutaneous cystolithotripsy in 2. Surgical removal of each stent required a mean of 1.5 interventions and a mean hospital stay of 4.4 days. CONCLUSIONS: At experienced centers combined endourological techniques can achieve successful and safe management of forgotten stents even in the pediatric age group. Thus, routine preprocedural tomography is a must in children with forgotten ureteral stents.


Asunto(s)
Remoción de Dispositivos/métodos , Reacción a Cuerpo Extraño/cirugía , Stents/efectos adversos , Uréter/cirugía , Cálculos Ureterales/cirugía , Ureteroscopía/métodos , Adolescente , Niño , Preescolar , Femenino , Estudios de Seguimiento , Reacción a Cuerpo Extraño/diagnóstico , Humanos , Masculino , Estudios Retrospectivos , Tomografía Computarizada por Rayos X , Uréter/diagnóstico por imagen
15.
Rheumatol Int ; 33(5): 1265-70, 2013 May.
Artículo en Inglés | MEDLINE | ID: mdl-23124696

RESUMEN

The purpose of the present study is to compare male patients with the fibromyalgia syndrome (FMS) with healthy individuals in terms of the sexual function. For the purposes of this study, 37 sexually active male FMS patients and 30 healthy controls were enrolled. The demographic data of the patients were recorded, and the widespread pain observed in FMS was graded with the help of the visual analogue scale (VAS 0-100 mm). Sexual function was assessed according to the international index of erectile function (IIEF) scoring system. The disease-related quality of life was measured with the help of the Short Form-36 quality of life questionnaire (SF-36 QoL). Levels of anxiety and depression observed in the patients were graded through the Hospital Anxiety and Depression Scale (HADS). Patients with FMS had significantly lower scores in each of the five domains of the IIEF in comparison with the healthy control group (p < 0.001). Patients' age and widespread pain were negatively correlated with the IIEF scores (p < 0.05). The SF-36 scores (physical functioning, role limitations due to physical problems, pain and general health perception) were observed to be positively correlated with the IIEF scores (p < 0.05). No significant relationship has been observed between the scores obtained from the domains of IIEF and the psychological status (p > 0.05). FMS leads to an impairment in the sexual function in male patients, which is especially strongly associated with the age, widespread pain and the quality of life.


Asunto(s)
Fibromialgia/complicaciones , Conducta Sexual , Disfunciones Sexuales Fisiológicas/etiología , Disfunciones Sexuales Psicológicas/etiología , Sexualidad , Adulto , Factores de Edad , Estudios de Casos y Controles , Estudios Transversales , Fibromialgia/diagnóstico , Fibromialgia/fisiopatología , Fibromialgia/psicología , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Erección Peniana , Valor Predictivo de las Pruebas , Calidad de Vida , Factores de Riesgo , Factores Sexuales , Disfunciones Sexuales Fisiológicas/fisiopatología , Disfunciones Sexuales Fisiológicas/psicología , Disfunciones Sexuales Psicológicas/fisiopatología , Disfunciones Sexuales Psicológicas/psicología , Encuestas y Cuestionarios , Turquía , Adulto Joven
16.
Cureus ; 15(7): e41322, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37539428

RESUMEN

OBJECTIVE: In this study, we analyzed the vertical geometry of the anterior communicating artery (AComA) complex with the aim to improve the surgical site orientation during aneurysm operations. Further, the geometric data that can contribute to the success of the surgical technique applied for AComA aneurysms are reported. METHODS: Computed tomography angiography data of the cerebral arteries of 100 patients who visited our clinic were analyzed. A three-dimensional examination was performed according to the Frankfurt horizontal plane (FHP) using the RadiAnt DICOM Viewer (Medixant, Poznan, Poland), and vertical measurements of the AComA complex were calculated. RESULTS: The Willis polygon values were found to be consistent with those in the literature. The mean height of the AComA complex was 30.58 ± 4.80 mm according to the FHP. CONCLUSIONS: Preoperative evaluation of the vertical geometry of the AComA complex is essential for AComA aneurysm surgery. The height of the AComA complex is a key parameter affecting intraoperative surgical site visibility. Preoperative calculation of the height of the AComA complex relative to FHP can facilitate intraoperative surgical site orientation.

17.
Turk Neurosurg ; 33(1): 110-117, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-35713261

RESUMEN

AIM: To uncover factors that can predict the development of C5 palsy before surgery by evaluating several different parameters. MATERIAL AND METHODS: A total of 177 patients who underwent surgery between 2015 and 2020 were included in the study. In total, C5 palsy was observed in 22 (12.4%) of our patients. The radiological and clinical data of the patients were retrospectively analyzed and added to the data. RESULTS: A total of 177 patients who satisfied the criteria were included in the study, among whom 117 (66.1%) and 60 (33.9%) were male and female, respectively. Patients with ossified posterior longitudinal ligament (OPLL) (92; 52.0%) needed surgery the most. C5 palsy developed in 16/92 (17.3%) patients who had surgery for OPLL. This result was statistically significant (p < 0.001). However, a significant difference in the postoperative Pavlov ratio was noted between both groups (p=0.027). The foraminal dimensions for the C5 palsy group were significantly lower than those for the non-C5 palsy group. CONCLUSION: Smaller C5 root foramina diameter measurements were the most important predictive factor for the development of C5 palsy after open-door cervical laminoplasty. Although the pathophysiology remains to be fully understood, ischemia-reperfusion injury supposedly plays a role therein.


Asunto(s)
Laminoplastia , Humanos , Masculino , Femenino , Laminoplastia/efectos adversos , Laminoplastia/métodos , Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/cirugía , Estudios Retrospectivos , Parálisis/epidemiología , Parálisis/etiología , Parálisis/cirugía , Radiografía
18.
J Urol ; 187(4): 1301-5, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22341291

RESUMEN

PURPOSE: A questionnaire was administered to urologists to evaluate attitudes and behaviors about protection from radiation exposure during fluoroscopy guided endourological procedures. MATERIALS AND METHODS: The questionnaire was e-mailed to 1,482 urologists, including urology residents, specialists and urologists holding all levels of academic degrees, between May and June 2011. The questionnaire administered to study participants was composed of demographic questions, and questions on radiation exposure frequency, and the use of dosimeters and flexible protective clothes. If a respondent reported not using dosimeters or protective clothes, additional questions asked for the reason. RESULTS: Of the 1,482 questionnaires 394 (26.58%) were returned, of which 363 had completed answers. A total of 307 physicians (84.58%) were exposed to ionizing radiation, of whom 79.61% stated that they perform percutaneous nephrolithotomy at the clinic. Fluoroscopy guidance was the initial choice of 96.19% of urologists during percutaneous nephrolithotomy. Despite the common use of lead aprons (75.24%) most urologists did not use dosimeters (73.94%), eyeglasses (76.95%) or gloves (66.67%) while 46.44% always used thyroid shields during fluoroscopy. When asked why they did not use protective clothing, the most common answers were that protective clothes are not ergonomic and not practical. CONCLUSIONS: Results clearly highlight the lack of use of ionizing radiation protection devices and dosimeters during commonly performed fluoroscopy guided endourological procedures among urologists in Turkey.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Exposición Profesional/prevención & control , Protección Radiológica , Urología , Adulto , Fluoroscopía/efectos adversos , Humanos , Encuestas y Cuestionarios , Turquía
19.
Urol Res ; 40(4): 317-25, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-21833788

RESUMEN

Aim of study was to present costs of forgotten ureteral stents extraction so as to distract attentions of the urologists on this issue. Medical files of 27 accessible patients who referred to our clinics between 2001 and 2010 because of forgotten ureteral stent were retrospectively analyzed. The indwelling time of double-j stents (DJS) was calculated from the time of its insertion. Costs related to radiological investigations, all invasive, and noninvasive interventions, duration of hospital stay, and medical treatments used were calculated. These estimations were based on 2010 prices determined by Turkey Ministry of Health. Mean age of the patients was 31.2 (8-86 years) years. Mean indwelling time of ureteral DJSs was 36.7 months (14-84 months). Seventy-one [extracorporeal shock wave lithotripsy (ESWL), n = 26; invasive/noninvasive interventions, n = 32] procedures were applied for 27 patients. In six patients without incrustation, after a single session of ESWL DJSs could be removed cystoscopically. A various combination of a multimodal therapy was used for other 21 patients. Total financial burden of 27 patients was US $ 34,300. Cost of treatment was estimated to be 6.9-fold (1.8- to 21-fold) higher than an average timely stent extraction. Financial burden of the treatments increased in parallel with the duration of the stent retention (p = 0.001). Management of forgotten DJS is time consuming, difficult, complicated, risky, and costly. Therefore; financial burden, increased labour loss, and impaired quality of life brought by the application of these modalities must not be forgotten.


Asunto(s)
Catéteres de Permanencia , Remoción de Dispositivos , Cuerpos Extraños/terapia , Stents/efectos adversos , Uréter , Cateterismo Urinario/instrumentación , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Análisis Costo-Beneficio , Femenino , Costos de la Atención en Salud , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
20.
Urol Res ; 40(3): 253-8, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21792673

RESUMEN

The objective of this study was to describe and present the initial results of a computer-based system that tracks ureteral stents and automatically sends a reminder through a short message service (SMS) to both the patient's and the urologist's mobile phones Using an integrated stent register program (SRP) and a stent extraction reminder program (SERP) with an electronic patient record program (EPRP) located within our hospital's computer network. In this system, the demographic data of all of the patients are recorded into the password-protected EPRP. After a stent is inserted, the surgeon enters the details of the operation into the EPRP. The SRP automatically asks the user to define the "optimal stent life (OSL)". The SERP checks the recorded patients daily and sends an SMS reminder to staff and patient when the OSL is reached. The SERP continues to send reminders via the SMS until stent is removed. We analyzed the success of the SMS recall system. A total of 186 patients received stents over an 11-month period. The patients in group-2 (n = 108) were recalled by the SERP, and the remainder of the patients (n = 78, group-1) were not included in the project. The mean delay from the designated OSL to the time of stent removal was 307 ± 118.6 (72-1,344) and 14.6 ± 2.06 (5-36) h in groups 1 and 2, respectively (p < 0.0001). Our initial results showed that the SRP and SERP prevent stent removal from being forgotten, thus preventing related medical and legal problems.


Asunto(s)
Remoción de Dispositivos , Sistemas Recordatorios , Stents , Envío de Mensajes de Texto , Obstrucción Ureteral/prevención & control , Registros Electrónicos de Salud , Humanos , Sistema de Registros
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