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1.
Molecules ; 29(2)2024 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-38257268

RESUMEN

This study successfully synthesized zinc oxide nanorod needles (ZnO-NRNs) using an environmentally friendly method employing Cymbopogon Proximus extract. The resulting ZnO-NRNs exhibited exceptional physicochemical and structural properties, confirmed through various characterization techniques, including UV-Vis spectrophotometry, dynamic light scattering (DLS), transmission electron microscopy (TEM), X-ray diffraction (XRD), and energy-dispersive X-ray spectroscopy (EDX). The analysis revealed a hexagonal wurtzite structure with high crystallinity, a 3.6 eV band gap, and a notably blue-shifted absorption band. ZnO-NRNs showed impressive photocatalytic activity, degrading Rhodamine B dye by 97% under UV and visible sunlight, highlighting their photostability and reusability. This green synthesis process offers cost effectiveness and environmental sustainability for practical applications.

2.
J Sleep Res ; 32(1): e13666, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-35670277

RESUMEN

The COVID-19 pandemic had a major impact on people of all ages. Adolescents' exposure to online learning is linked to excessive screen time on digital devices, which leads to poor sleep quality. This study aimed to investigate the association between screen time on different electronic devices and sleep quality among adolescents in the United Arab Emirates. This study was based on a self-reported questionnaire, which was administered online to school-aged adolescents (aged 12-19 years). The multicomponent questionnaire collected information on sociodemographic characteristics, sleep quality using the Pittsburgh Sleep Quality Index (PSQI), and screen time (minutes) on TV, TV-connected devices, laptops, smartphones, and tablets on weekdays, weeknight, and weekends using the Screen Time Questionnaire (STQ). Univariate and multivariate analyses were used to identify factors correlated with poor sleep quality. A total of 1720 adolescents were recruited from private and public schools (mean age 14.6 ± 1.97 years). The mean PSQI score was 8.09 ± 3.37, and 74.3% of participants reported poor sleep (cutoff score >5). Mean scores were highest for the sleep latency (1.85 ± 0.97) and sleep disturbance (1.56 ± 0.62) domains. The highest STQ score was observed for smartphones, with a median screen time of 420 min on weekdays and 300 min on weekends. Screen time related to smartphones on weekends (p = 0.003) and increased screen time in bed (p < 0.001) were significantly associated with poor sleep. Our results confirmed the correlation between sleep and screen time in adolescents. The results may inform educational polices that target screen time and sleep among adolescents during and after the COVID-19 pandemic.


Asunto(s)
COVID-19 , Calidad del Sueño , Humanos , Adolescente , Niño , Tiempo de Pantalla , Emiratos Árabes Unidos/epidemiología , Pandemias , Estudios Transversales , Sueño , Encuestas y Cuestionarios
3.
Nanotechnology ; 35(8)2023 Dec 08.
Artículo en Inglés | MEDLINE | ID: mdl-37816334

RESUMEN

Electrodeposited polyaniline over the carbon nanotubes fiber (CNTF) has been investigated as potential candidate to substitutes the Pt based auxiliary electrodes in unidimensional fibrous solar cells. CNTF, with excellent electrical and mechanical properties, modified with conducting polymer (polyaniline) via facile electrodeposition process which employed as cathodic materials showed efficient electrochemical reduction of triiodide ions in the fiber shaped dye-sensitized solar cells. Scanning electron microscopic analysis showed the efficacious integration of conducting polymer over the CNTF surface. The admirable electrocatalytic behavior of the fabricated electrode has investigated by electrochemical impedance spectroscopy and cyclic voltammetry. Current density and voltage (J-V) curves are used to quantify the photovoltaic performance of devices with different counter electrodes with fixed photoanode. With lower peak to peak separation, improved current density and better fill factor, exhibited the superior efficiency of modified electrode (PANI@CNTF). As compared to pristine fiber, polyaniline modification showed the outstanding performance with improved photovoltaics and electrochemical parameters measured by theJ-Vand CV curves, respectively.

4.
BMC Med Educ ; 23(1): 968, 2023 Dec 18.
Artículo en Inglés | MEDLINE | ID: mdl-38110914

RESUMEN

BACKGROUND: Regardless of a proliferation of interest in reducing unsafe practices in healthcare, threats to patient safety (PS) remain high. Moreover, little attention has been paid towards the role of interprofessional education (IPE) in enhancing PS. This qualitative study was conducted to unfold the insights of the senior medical, dental and health sciences students at the University of Sharjah (UoS) in the United Arab Emirates (UAE) about PS in an online IPE-based workshop. METHODS: This inductive thematic analysis study was conducted on senior medical and health students at the Colleges of Medicine, Dental Medicine, Health Sciences, and Pharmacy of UoS. During an online workshop, students discussed plausible solutions for four real practice-based clinical scenarios with elements of unsafe healthcare practices. During the breakout rooms, the students exhibited high level of articulation and proactively participated in discussions. The data from the online workshop were transcribed and then coding, categorizing, and labelling of recurrent themes were carried out. Multiple individual deliberations, consolidation, incorporation of the identified preliminary themes, and merging and reorganizing sub-themes led to a final thematic framework. RESULTS: This work delved into the perspectives of 248 students regarding teamwork, communication, problem-solving, and other aspects concerning PS in interprofessional settings in an online workshop. The iterative process of data transcription, curating and qualitative analysis surfaced 32 codes. Later, the inductive themaric analysis yielded five themes with distinct yet interconnected nested subthemes in the context of PS in IPE settings. These themes of information sharing and grounding (problem-solving, social skills), maintaining communication (clinical reasoning, shared mental model), executing interprofessional activities (collaborative practice, collaboration scripts), professional cognitive abilities (cognitive maturity, metacognition), and negotiating professional identities (systematic change, socio-economic scaffolding) emerged as fundamental pillars for enhancing PS in healthcare. CONCLUSION: Our study demonstrated the outcome of an innovative and team-based workshop which embedded PS within a scaffold of IPE environment. This research calls for incorporation of the emerging areas of clinical reasoning, problem solving, collaborative practice, and shared mental model into medical curricula for structured IPE in improving PS domains in medical education. These findings underscore the need for multifaceted dimensions of IPE imperatives for cultivating collaborative competence.


Asunto(s)
Relaciones Interprofesionales , Seguridad del Paciente , Humanos , Educación Interprofesional , Investigación Cualitativa , Curriculum
5.
Molecules ; 27(13)2022 Jul 04.
Artículo en Inglés | MEDLINE | ID: mdl-35807545

RESUMEN

Coming into the second year of the pandemic, the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants continue to be a serious health hazard globally. A surge in the omicron wave, despite the discovery of the vaccines, has shifted the attention of research towards the discovery and use of bioactive compounds, being potential inhibitors of the viral structural proteins. The present study aimed at the green synthesis of zinc oxide (ZnO) nanoparticles with seed extracts of Nigella sativa and Pimpinella anisum-loaded nanostructured oil carriers (NLC)-using a mixture of olive and black seed essential oils. The synthesized ZnO NLC were extensively characterized. In addition, the constituent compounds in ZnO NLC were investigated as a potential inhibitor for the SARS-CoV-2 main protease (3CLpro or Mpro) where 27 bioactive constituents, along with ZnO in the nanostructure, were subjected to molecular docking studies. The resultant high-score compounds were further validated by molecular dynamics simulation. The study optimized the compounds dithymoquinone, δ-hederin, oleuropein, and zinc oxide with high docking energy scores (ranging from -7.9 to -9.9 kcal/mol). The RMSD and RMSF data that ensued also mirrored these results for the stability of proteins and ligands. RMSD and RMSF data showed no conformational change in the protein during the MD simulation. Histograms of every simulation trajectory explained the ligand properties and ligand-protein contacts. Nevertheless, further experimental investigations and validation of the selected candidates are imperative to take forward the applicability of the nanostructure as a potent inhibitor of COVID-19 (Coronavirus Disease 2019) for clinical trials.


Asunto(s)
Tratamiento Farmacológico de COVID-19 , Nanoestructuras , Nigella sativa , Pimpinella , Óxido de Zinc , Cisteína Endopeptidasas/química , Humanos , Ligandos , Simulación del Acoplamiento Molecular , Simulación de Dinámica Molecular , Nigella sativa/metabolismo , Péptido Hidrolasas/metabolismo , Extractos Vegetales/farmacología , Inhibidores de Proteasas/química , SARS-CoV-2 , Semillas/metabolismo , Proteínas no Estructurales Virales/metabolismo , Óxido de Zinc/farmacología
6.
BMC Oral Health ; 21(1): 197, 2021 04 19.
Artículo en Inglés | MEDLINE | ID: mdl-33874916

RESUMEN

BACKGROUND: Candida's potential association with dental caries has previously been reported in children. This research aimed at investigating the associations between Candida species in whole saliva and dental and periodontal health indices in a sample of adult patients. METHODS: A cross-sectional study involving 160 patients investigated the associations between Candida species collected by oral rinse technique, and Decayed, Missing, and Filled Surfaces (DMFS), and periodontal health indices. Chi-square and Independent Samples t-test were used to assess the associations between Candida carriage and confounding variables. Binary logistic regression was used to assess association strengths between Candida carriage and DMFS, adjusted for socio-demographic variables, diabetes mellitus and plaque index. RESULTS: Candida colonies were identified in 49 (30.6%) patients with CFUs ranging from 103 to 105 colonies per mL. The quantity of Candida CFUs increased with age (r = 0.200; p < 0.05). Among all dental and periodontal health indices, only DMFS was significantly associated with higher values of Candida carriage (p = 0.034), and this association was independent from sex, age, smoking, diabetes mellitus and plaque index (OR: 1.014; 95% CI 1.0-1.03; p = 0.048). CONCLUSION: The association between Candida species in whole saliva and DMFS reported here supports an etiological role of Candida in dental cariogenesis among adults.


Asunto(s)
Caries Dental , Adulto , Candida , Niño , Estudios Transversales , Índice CPO , Caries Dental/epidemiología , Índice de Placa Dental , Humanos , Saliva
7.
Health Qual Life Outcomes ; 18(1): 182, 2020 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-32539861

RESUMEN

BACKGROUND: Nearly a quarter of the population in the UAE has type 2 diabetes mellitus (T2DM), and this medical condition is associated with poorer oral health. The effects on oral health-related quality of life (OHRQoL), however, have not been examined in this population. Therefore, the objective of this study was to assess the impact of oral health problems, such as caries and periodontitis, on OHRQoL among Arab patients with and without T2DM. METHODS: This matched case-control study included 88 diabetic and 88 non-diabetic participants recruited from University Dental Hospital Sharjah and University Hospital Sharjah, UAE. Participants completed a sociodemographic questionnaire as well as the Oral Health Impact Profile short form (OHIP-14), which measures OHRQoL. Clinical examinations were conducted to assess participants' dental caries status, using the Decayed Missing Filled Teeth (DMFT) Index, and periodontal condition, via clinical attachment loss (CAL) dichotomized to CAL < 3 mm and CAL ≥3 mm. Linear regression models were used to identify the association among OHIP domains, clinical attachment loss, DMFT scores, and diabetes status. RESULTS: The mean age of participants was 43.0 years. A significantly (p = 0.01) higher proportion of diabetic patients (23%) had a CAL ≥3 mm than non-diabetic patients (10%). No significant differences in OHIP scores were observed between diabetic and non-diabetic patients. The results of the linear regression suggested that irrespective of diabetic status, DMFT scores were significantly associated with physical disability, physical pain, psychological discomfort, and psychological disability, as well as total OHIP scores. CAL was significantly associated with the handicap domain. Among non-diabetic patients, OHIP scores were significantly associated with DMFT scores in five OHIP domains (functional limitation, physical disability, physical pain, psychological discomfort, psychological disability), as well as total OHIP scores. Among diabetic patients, CAL was significantly associated with both the social disability and handicap domains, while only the handicap domain reached statistical significance among non-diabetic patients. CONCLUSIONS: Participants who had decayed teeth, irrespective of their diabetic status, reported substantial physical and psychological impacts on OHRQoL. CAL also had a significant impact on OHRQoL, being primarily associated with the OHIP handicap domain in both diabetic and non-diabetic patients.


Asunto(s)
Diabetes Mellitus Tipo 2/complicaciones , Salud Bucal , Calidad de Vida , Adulto , Estudios de Casos y Controles , Caries Dental/complicaciones , Caries Dental/psicología , Diabetes Mellitus Tipo 2/psicología , Personas con Discapacidad/psicología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Periodontitis/complicaciones , Periodontitis/psicología , Encuestas y Cuestionarios , Pérdida de Diente/complicaciones , Pérdida de Diente/psicología , Emiratos Árabes Unidos
8.
BMC Pediatr ; 20(1): 245, 2020 05 25.
Artículo en Inglés | MEDLINE | ID: mdl-32450837

RESUMEN

BACKGROUND: Anxiety disorders are common among children and adolescents. However, there is a paucity of up-to-date data on the prevalence and correlates of anxiety-related disorders among children and adolescents in the United Arab Emirates (UAE). METHODS: We conducted a cross sectional study to determine the prevalence of specific anxiety-related disorders (e.g., generalized anxiety disorder, panic disorder, separation anxiety, social anxiety) in the UAE, and identify correlations between these disorders and adolescents' demographic variables. Participants were 968 adolescents aged 13-18 years attending secondary schools across the UAE. Convenience sampling was used to recruit participants. We collected demographic information and data about participants' anxiety levels. Anxiety was assessed using the Arabic and English versions of the Screen for Child Anxiety Related Disorders scale. Univariate analyses (independent sample t-tests and analysis of variance) were performed to evaluate factors affecting participants' anxiety scores. Chi-square tests were used to compare factors associated with anxiety disorders. RESULTS: Participants' mean age was 16 ± 1.8 years, and 65.8% were female. The overall prevalence of anxiety disorders was 28%, with this being significantly higher in girls (33.6%) than boys (17.2%) (p < 0.0001). Participants aged < 16 years had higher generalized anxiety, separation anxiety, and social anxiety scores compared with those aged ≥16 years (p ≤ 0.05). Those from households with a maid had significantly higher generalized anxiety, panic disorder, separation anxiety, and significant school avoidance scores than those without a maid (p ≤ 0.05). In addition, participants from middle and low economic backgrounds had higher separation anxiety scores compared with children from high economic backgrounds (p ≤ 0.05). The multivariate analysis showed the main associated factors with anxiety were gender (being female, p < 0.001) and caregiver (other than mother and father together, p < 0.001). CONCLUSIONS: We found a high incidence of anxiety-related disorders among school-aged adolescents in the UAE, with girls being more affected than boys. This suggests that age-appropriate initiatives are urgently needed to reduce the high rate of anxiety-related disorders. It may also be necessary to further investigate the two main associated factors with anxiety identified in this study (being female and non-parental caregivers).


Asunto(s)
Trastornos de Ansiedad , Ansiedad , Adolescente , Ansiedad/epidemiología , Trastornos de Ansiedad/epidemiología , Niño , Estudios Transversales , Femenino , Humanos , Masculino , Prevalencia , Emiratos Árabes Unidos/epidemiología
9.
J Oral Rehabil ; 47(4): 473-479, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-31860124

RESUMEN

BACKGROUND: Dentine hypersensitivity is a frequent oral complaint that is usually associated with several factors including diet and oral hygiene practices. OBJECTIVE: The aim of this study was to assess the prevalence, severity and correlates of dentine hypersensitivity and dentine exposure-related risk indicators in a sample from six Arab countries. METHODS: A multinational cross-sectional study was conducted on a sample of 2924 participants, attending dental practices, aged 18-35 years from six Arab countries. Trained examiners assessed dentine hypersensitivity using the Schiff scale and scored the tooth with the highest value in each sextant. Participants were asked to complete a questionnaire that assessed the frequency of drinking and eating acidic foods and their oral health habits. RESULTS: Overall, the Schiff score 1 was found in 938 (32.6%), score 2 in 613 (21%) and score 3 in 274 (9%) of the participants. There was variation between countries with Saudi Arabia (13.9%) and Oman (15%) having the highest prevalence of hypersensitivity and Kuwait (2.2) and Jordan the lowest (4.8%). Participants who experienced toothache and difficulty eating once a day were significantly more likely to have Schiff score 2 or 3 (OR: 2.51, 95% CI: 1.54-2.87; OR: 1.34, 95% CI: 1.04-1.73, respectively). Furthermore, drinking soft drinks once a day was also significantly associated with dentine exposure (OR: 1.4, 95% CI: 1.19, 1.65). CONCLUSION: In this cross-sectional study, dentine sensitivity and exposure were common in Arab patient populations.


Asunto(s)
Sensibilidad de la Dentina , Adolescente , Adulto , Árabes , Estudios Transversales , Dentina , Humanos , Prevalencia , Arabia Saudita , Adulto Joven
10.
Molecules ; 25(18)2020 Sep 14.
Artículo en Inglés | MEDLINE | ID: mdl-32937751

RESUMEN

Nanoparticles (NPs) have unique properties compared to their bulk counterparts, and they have potentials for various applications in many fields of life science. Green-synthesized NPs have garnered considerable interest due to their inherent features such as rapidity, eco-friendliness and cost-effectiveness. Zinc oxide nanoparticles (ZnO NPs) were synthesized using an aqueous extract of Kalanchoe blossfeldiana as a reducing agent. The resulting nanoparticles were characterized via X-ray diffraction (XRD), dynamic light scattering (DLS), UV-Vis spectroscopy, photoluminescence (PL), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS). The antimicrobial potential of the synthesized ZnO NPs against bacterial and fungal strains was examined by the disk diffusion method, and they showed a promising antibacterial and antifungal potential. The catalytic activity of the synthesized ZnO NPs in reducing methylene blue (MB) and eosin was studied via UV-Vis spectroscopy. The decolorization percentages of the MB and Eosin Y dyes were 84% and 94%, respectively, which indicate an efficient degradation of the ZnO NPs. In addition, the cytotoxic activity of the ZnO NPs on the HeLa cell line was evaluated via in vitro assay. The MTT assay results demonstrate a potent cytotoxic effect of the ZnO NPs against the HeLa cancer cell line.


Asunto(s)
Antiinfecciosos/farmacología , Nanopartículas del Metal/química , Óxido de Zinc/química , Óxido de Zinc/farmacología , Antiinfecciosos/química , Catálisis , Ensayos de Selección de Medicamentos Antitumorales , Tecnología Química Verde , Células HeLa , Humanos , Kalanchoe/química , Luz , Luminiscencia , Microscopía Electrónica de Rastreo , Microscopía Electrónica de Transmisión , Fotoquímica/métodos , Extractos Vegetales/química , Sustancias Reductoras/química , Dispersión de Radiación , Espectrofotometría Ultravioleta , Difracción de Rayos X
11.
East Mediterr Health J ; 24(7): 653-663, 2018 Sep 06.
Artículo en Inglés | MEDLINE | ID: mdl-30215475

RESUMEN

BACKGROUND: Interventions to promote healthy eating in adolescents are needed in the United Arab Emirates. To design effective interventions, adolescent eating behaviours need to be understood. AIMS: This study aimed to describe eating behaviours of adolescents in Dubai and the factors associated with fruit and vegetable intake. METHODS: This was a sequential explanatory study using a mixed methods approach. Ten of the 34 Arabic high schools in Dubai were randomly selected and students in grades 10-12 were included. Data were collected on self-reported fruit and vegetables intake, eating behaviours, food availability and sociodemographic variables. In the qualitative phase, 14 students were interviewed about their eating behaviour. RESULTS: A total of 620 students were included: 57% were boys and most reported medium/high family affluence. Only 28% of the participants met the recommended daily fruit and vegetable intake, with significantly more males than females meeting it (P < 0.01). Lunch was the most frequently eaten meal, breakfast was frequently skipped, and there were high levels of fast food and soft drink consumption. Adequate fruit and vegetable intake was positively associated with increased lunch frequency, being male, parental support for healthy eating, and positive perception of family meals. CONCLUSIONS: There are significant differences in eating habits between Emirati male and female adolescents. Lunch, as the main family meal, faces threats because of modern working hours. The gender-specific social context may require targeted interventions to achieve optimal outcomes in each group.


Asunto(s)
Dieta/estadística & datos numéricos , Frutas , Verduras , Adolescente , Conducta Alimentaria , Femenino , Humanos , Masculino , Psicología del Adolescente/estadística & datos numéricos , Factores Sexuales , Factores Socioeconómicos , Encuestas y Cuestionarios , Emiratos Árabes Unidos , Adulto Joven
12.
Clin Oral Implants Res ; 25(1): 46-51, 2014 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23735197

RESUMEN

OBJECTIVES: To determine the difference in oral health-related quality of life (OHRQoL) in patients who received mandibular 2-implant overdentures and conventional dentures in a pragmatic international study. MATERIALS AND METHODS: In this prospective study, data were gathered from 203 edentulous patients (mean age, 68.8; SD: 10.4 years) at eight centres in North America, South America and Europe. The patients were provided with new mandibular conventional dentures or implant overdentures supported by 2 implants and ball attachments and opposed by conventional dentures. At baseline and at 6 months post-treatment, patients rated their oral health-related quality of life using the OHIP-20. RESULTS: A significantly higher proportion of the participants in the implant group in North America reported improvement in both the psychological and the handicap domains, compared to those who received conventional dentures (93% vs. 52%; P < 0.05). In South America, 100% of participants who received implant overdentures reported improvement in physical pain, compared to 66% in the conventional group (P < 0.05). Differences in mean change scores among those who expressed improvement were not significantly different between sites or treatments. CONCLUSION: Mandibular 2-implant overdentures are more likely than conventional dentures to improve OHRQL for edentulous patients. Cultural differences were also observed in the impact of implant overdentures on the different domains of the OHIP-20.


Asunto(s)
Prótesis Dental de Soporte Implantado , Prótesis de Recubrimiento , Salud Bucal , Satisfacción del Paciente , Anciano , Implantes Dentales , Retención de Dentadura , Dentadura Completa Inferior , Femenino , Humanos , Masculino , Mandíbula , Estudios Prospectivos , Calidad de Vida , Encuestas y Cuestionarios
13.
J Pharm Bioallied Sci ; 16(Suppl 2): S1461-S1464, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38882801

RESUMEN

Oral submucous fibrosis (OSF) is a chronic disorder prevalent in South and Southeast Asia and is mainly related to the habit of chewing betel quid. Although there are numerous South-Asian studies about OSF, there is no study that evaluates the awareness of OSF among expatriate populations of South-Asian origin. Evaluated the awareness of OSF among South-Asian expatriate patients reporting to a dental hospital in Sharjah. Prevalidated questionnaires were given to 150 expatriate patients of South-Asian origin with quid-chewing habit reporting to the teaching clinics of a dental hospital in the United Arab Emirates. Among the 150 patients, 103 responded to the questionnaire. Among the 103 respondents, 11.65% were aware of OSF. Respondents living in shared residency and labor camps had significantly (P = 0.43) lower awareness of OSF compared to respondents living with their families. The results of our study show that the awareness of OSF is lower among the respondents living in labor camps and shared residencies. The younger respondents had more awareness of OSMF and were more likely to quit the quid-chewing habit.

14.
Int J Nanomedicine ; 19: 4451-4464, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38799694

RESUMEN

Introduction: Researchers are increasingly favouring the use of biological resources in the synthesis of metallic nanoparticles. This synthesis process is quick and affordable. The current study examined the antibacterial and anticancer effects of silver nanoparticles (AgNPs) derived from the Neurada procumbens plant. Biomolecules derived from natural sources can be used to coat AgNPs to make them biocompatible. Methods: UV-Vis spectroscopy was used to verify the synthesis of AgNPs from Neurada procumbens plant extract, while transmission electron microscopy (TEM), photoluminescence (PL) spectroscopy, dynamic light scattering (DLS), and Fourier transform infrared spectroscopy (FTIR) were used to characterize their morphology, crystalline structure, stability, and coating. Results: UV-visible spectrum of AgNPs shows an absorption peak at 422 nm, indicating the isotropic nature of these nanoparticles. As a result of the emergence of a transmission peak at 804.53 and 615.95 cm-1 in the spectrum of the infrared light emitted by atoms in a sample, FTIR spectroscopy demonstrated that the Ag stretching vibration mode is metal-oxygen (M-O). Electron dispersive X-ray (EDX) spectral analysis shows that elementary silver has a peak at 3 keV. Irradiating the silver surface with electrons, photons, or laser beams triggers the illumination. The emission peak locations have been found between 300 and 550 nm. As a result of DLS analysis, suspended particles showed a bimodal size distribution, with their Z-average particle size being 93.38 nm. Conclusion: The findings showed that the antibacterial action of AgNPs was substantially (p≤0.05) more evident against Gramme-positive strains (S. aureus and B. cereus) than E. coli. The biosynthesis of AgNPs is an environmentally friendly method for making nanostructures that have antimicrobial and anticancer properties.


Asunto(s)
Tecnología Química Verde , Nanopartículas del Metal , Plata , Nanomedicina Teranóstica , Plata/química , Plata/farmacología , Nanopartículas del Metal/química , Tecnología Química Verde/métodos , Humanos , Nanomedicina Teranóstica/métodos , Antibacterianos/farmacología , Antibacterianos/química , Extractos Vegetales/química , Extractos Vegetales/farmacología , Antineoplásicos/farmacología , Antineoplásicos/química , Invasividad Neoplásica/prevención & control , Tamaño de la Partícula , Pruebas de Sensibilidad Microbiana , Espectroscopía Infrarroja por Transformada de Fourier , Línea Celular Tumoral , Neoplasias/tratamiento farmacológico , Neoplasias/patología , Escherichia coli/efectos de los fármacos , Staphylococcus aureus/efectos de los fármacos
15.
J Epidemiol Glob Health ; 14(2): 349-362, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38407717

RESUMEN

OBJECTIVES: To investigate the clinical and epidemiological factors associated with severe COVID-19 cases in hospitalized patients across two emirates within the United Arab Emirates (UAE). METHODS: A retrospective observational analytical study analysed data from 738 medical records and conducted 573 in-depth interviews with patients hospitalized across multiple healthcare centers in the UAE, between 29 January 2020 and 14 October 2021. Regression analysis predicted risk factors for COVID-19 severity. RESULTS: Main risk factors identified were crowding (aOR 1.919; 95%CI 1.144, 3.221), obesity (aOR 2.383; 95%CI 1.332, 4.263), diabetes (aOR 11.14; 95%CI 2.653-46.797), severe dehydration (aOR 3.219; 95%CI 2.161, 4.795), cough or sore throat (aOR 1.607; 95%CI 1.032, 2.502), shortness of breath (aOR 1.921; 95%CI 1.294, 2.853), increased days from symptom onset to admission (aOR 1.055; 95%CI 1.006, 1.105), elevated ANC (aOR 1.263, 95%CI 1.121, 1.424), and AST/SGOT (aOR 1.055, 95% CI 1.016, 1.095). Protective factors included smoking (aOR 0.367; 95%CI 0.182, 0.740), first dose of COVID-19 vaccination (aOR 0.595; 95%CI 0.377, 0.93), higher oxygen saturation (aOR 0.853; 95%CI: 0.801, 0.907) and elevated ALC (aOR 0.540; 95%CI 0.323, 0.905). CONCLUSION: Identifying risk factors is crucial for high-risk individuals who may require closer monitoring to improve their outcomes. This can provide guidance for surveillance systems and early detection strategies to mitigate the impact of future outbreaks.


Asunto(s)
COVID-19 , Hospitalización , SARS-CoV-2 , Índice de Severidad de la Enfermedad , Humanos , Emiratos Árabes Unidos/epidemiología , COVID-19/epidemiología , Estudios Retrospectivos , Masculino , Femenino , Persona de Mediana Edad , Adulto , Factores de Riesgo , Hospitalización/estadística & datos numéricos , Anciano , Adulto Joven , Adolescente
16.
Materials (Basel) ; 16(6)2023 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-36984236

RESUMEN

This study aimed to evaluate the effect of seven different decontamination methods (water, ZirCleanTM, 37% phosphoric acid, 9.5% hydrofluoric acid, Al2O3 sandblasting, low-speed dental stone, and high-speed dental stone) on the fracture resistance, microstructure, and surface roughness of monolithic and multilayered zirconia. The as-received and sandblasted zirconia was used as a control. One-way ANOVA and t-test were performed. As-received monolithic zirconia was stronger (856 ± 94 MPa) than multilayered zirconia (348.4 ± 63 MPa). Only phosphoric acid (865 ± 141 MPa) and low-speed dental stone (959 ± 116 MPa) significantly increased the flexural strength of sandblasted monolithic zirconia (854 ± 99 MPa), but all tested decontamination methods except phosphoric acid (307 ± 57 MPa) and Al2O3 (322 ± 69 MPa) significantly increased the flexural strength of sandblasted multilayered zirconia (325 ± 74 MPa). Different decontamination methods did not significantly affect the flexural modulus, but introduced irregularities in the crystal as well as deep surface flaws in both types of zirconia. The surface of sandblasted monolithic zirconia is more resistant to change than multilayered zirconia. Among different decontamination methods, a low-speed dental stone could be beneficial as it significantly increased the surface roughness and fracture resistance of both types of zirconia.

17.
Eur J Dent ; 17(3): 749-755, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37059445

RESUMEN

OBJECTIVES: The purpose of this pilot study is to assess the United Arab Emirates dentists' preparedness to manage medical emergencies. MATERIALS AND METHODS: Ninety-seven licensed dentists participated in this study. Dentists responded to self-administrated questionnaires that contained 23 questions divided into five parts. The first part collected data on participants' sex, years of experience, and whether they are general dental practitioner (GDP) or specialists. The second part included seven questions that asked participants to indicate if they took medical history, obtained vital signs, and attended basic life support courses. The third part included six multiple choice questions regarding the availability of emergency drugs in the dental clinic. The fourth part consisted of three multiple-choice questions that assessed the dentists' immediate response to a medical emergency. Finally, the fifth part comprised four questions to evaluate the dentists' knowledge of proper treatment of special emergency cases they may encounter in the dental offices. RESULTS: Out of the 97 participants, only 51% (N = 49) indicated that they can handle emergencies such as anaphylactic shock and syncope in the dental office. The majority of the dentists (80%) indicated that they have emergency kits. Only 46% of the specialists and 42% of the GDPs were able to correctly plan extractions in a patient with a prosthetic heart valve. Less than half of the participants (N = 35, 36%) were able to correctly answer the question regarding management of a foreign-body aspiration by attempting Heimlich/Triple maneuver. CONCLUSIONS: Within the limitations of this study, dentists need further hands-on training to improve their skills and knowledge about medical emergencies that could occur in the dental settings. Furthermore, we recommend that guidelines should be available in the clinic to strengthen the dentists' ability to deal with medical emergencies.

18.
Front Oral Health ; 4: 1160428, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37441619

RESUMEN

Background: Obesity and dental caries among adolescents is a growing worldwide public health issue. They share some common and modifiable influences. The objective of this study was to evaluate the association between obesity and dental caries among adolescents in the United Arab Emirates (UAE). Methods: This pilot cross-sectional study enrolled 161 adolescents 13-19 years old from private and public schools in the UAE. Participants were classified as normal weight, underweight, overweight or obese. Dental caries was diagnosed according to the criteria recommended by the World Health Organization (WHO). Independent t-tests were used to compare average number of decayed, missing and filled surfaces (DMFS) by age, sex, school type, mothers' employment, BMI categories, waist circumference, oral health habits and plaque index. Additionally, a multiple linear regression model was applied to analyze the association between BMI, waist circumference and dental caries, adjusted for confounding factors considered in this study. Results: The average age of the participants was 16.2 ± 1.4 years old. The prevalence of overweight/obesity was 42% (N = 68) measured by BMI. In addition, 82% (N = 132) had average waist circumference and 18% (N = 29) with above average waist circumference. Overall, the average DMFS score was 4.35 ± 4.5, with significantly lower dental caries rates among girls ([3.3 (SD:4.0)] than boys (6.7 (SD:5.3), (p < 0.05). The linear regression model revealed that, being a male, attending a public school and having average waist circumference were all positively and significantly associated with dental caries (p < 0.05). Conclusion: Obesity measured by waist circumference was significantly associated with dental caries among adolescents in the UAE. Further research is required to investigate the complex association between obesity and dental caries and how dietary habits, oral hygiene habits, and parental socioeconomic status mediate the association between obesity and dental caries.

19.
Environ Pollut ; 332: 121946, 2023 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-37307860

RESUMEN

The aim of the present study was a qualitative assessment of potential microplastics (MPs) in the sewage effluent collected from a local sewage treatment plant located in Riyadh City, Saudi Arabia. The composite samples of domestic sewage effluent were subjected to UV (ultraviolet) light-induced zinc oxide nanoparticles (ZnONPs) mediated photocatalysis. The first phase of the study included the synthesis of the ZnONPs with an extensive characterization. The synthesized nanoparticles were 220 nm in size with a characteristic spherical/hexagonal shape. These NPs were then used at three different concentrations (10 mM, 20 mM, and 30 mM) for the UV light-induced photocatalysis. A shift in the Raman spectra on photodegradation mirrored the surface changes of the functional groups shown by the FTIR spectra; presence of functional groups containing oxygen and C-C bonds associated with oxidation and chain scission. SEM micrographs showed photodegraded particles. Complementary elemental maps from the EDS analysis showed the presence of C, O, and Cl suggesting the potential presence of MPs. The O/C ratio was used to assess potential oxidation degree. In addition, an evaluation of the toxicological effects of the potential MPs in the sewage effluent on Nile tilapia (Oreochromis niloticus) exposed to the effluent at two concentrations (50% and 75%) elicited a marked response in the endpoints evaluated; EROD activity, MDA (malondialdehyde), 8-oxo-2'-deoxyguanosine levels in and AChE (acetylcholinesterase) activity in the brain. Thus, the key results provide new insights into the use of clean technologies to combat global MP pollution in aquatic ecosystems.


Asunto(s)
Cíclidos , Nanopartículas , Óxido de Zinc , Animales , Cíclidos/metabolismo , Microplásticos/metabolismo , Óxido de Zinc/química , Plásticos/metabolismo , Aguas del Alcantarillado , Acetilcolinesterasa/metabolismo , Ecosistema
20.
Front Public Health ; 11: 1182758, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37680271

RESUMEN

Background: College students report disturbed sleep patterns that can negatively impact their wellbeing and academic performance. Objectives: This study examined the effect of a 4-week sleep hygiene program that included sleep education and actigraph sleep trackers (FITBITs) on improving sleep quality and reducing psychological worry without control group. Design settings and participants: A pilot quasi-experimental design, participants were randomly selected medical and health sciences from a university students in the United-Arab-Emirates. Methods: Students were asked to wear FITBITs and log their daily sleep data and completed the Pittsburgh Sleep Quality Index (PSQI) and Penn State Worry Questionnaire (PSWQ). Extensive sleep hygiene education was delivered via lectures, a WhatsApp group, and the Blackboard platform. In total, 50 students completed pre-and post-assessments and returned FITBIT data. Results: There was a significant difference in the prevalence of good sleep postintervention compared with pre-intervention (46% vs. 28%; p = 0.0126). The mean PSQI score was significantly lower post-intervention compared with pre-intervention (6.17 ± 3.16 vs. 7.12.87; p = 0.04, Cohen's d 0.33). After the intervention, subjective sleep quality, sleep latency, and daytime dysfunction were significantly improved compared with pre-intervention (p < 0.05). In addition, FITBIT data showed total sleep time and the number of restless episodes per night were significantly improved postintervention compared with pre-intervention (p = 0.013). The mean PSWQ score significantly decreased from pre-intervention to p = 0.049, Cohen' d = 0.25. The correlation between PSQI and PSWQ scores was significant post-intervention (ß = 0.40, p = 0.02). Conclusion: Our results may inform university educational policy and curricular reform to incorporate sleep hygiene awareness programs to empower students and improve their sleep habits.


Asunto(s)
Higiene del Sueño , Calidad del Sueño , Humanos , Escolaridad , Estudiantes , Sueño
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