RESUMEN
To determine the incidence and characteristics of measles, cases reported to the Health Center for Diseases Control 2000-2002 were reviewed. Demographics data, vaccination status and its relation to occurrence the disease were analysed. A total of 729 cases (270 women,162, 269, 298, over the 3 years) were reported. The annual incidence rates over the 3 years were 7.1, 11.9 and 12.7 for each 10(5) population. In full vaccinated subjects, 46.5% of the cases occurred and 39.9% of the cases had not been vaccinated. Because of the high incidence rate of measles both in vaccinated and unvaccinated individuals, paying more attention to proper shipping and storing of vaccine, and even catch-up immunization for increasing herd immunity are recommended.
Asunto(s)
Accesibilidad a los Servicios de Salud , Programas de Inmunización/estadística & datos numéricos , Vacuna Antisarampión/provisión & distribución , Sarampión/epidemiología , Sarampión/prevención & control , Adolescente , Adulto , Niño , Preescolar , Demografía , Femenino , Humanos , Incidencia , Lactante , Recién Nacido , Irán/epidemiología , Masculino , Sarampión/etiología , Servicios Preventivos de Salud , Gobierno EstatalRESUMEN
We evaluated the seroprevalence of measles antibody and response to measles reimmunization in 590 previously vaccinated adolescents and young adults; 263 were seronegative. To differentiate between primary and secondary vaccine failure, anti-measles IgM and IgG titres were assessed again 2-4 weeks after revaccination in 144 (105 seronegative, 39 seropositive) individuals: 75 seronegative participants responded to revaccination anamnestically (P < 0.001) and developed immunity, 11 also showed IgM response (probably primary vaccine failure); 38 seropositive participants remained seroprotected without significant increase in antibody titre (P = 0.577). Primary vaccine failure was 4.7%; secondary vaccine failure was 27.1%. After revaccination, 87.3% were seroprotected.