Nonlinear Dynamic Analysis of a Piezoelectric Energy Harvester with Mechanical Plucking Mechanism.

In this study, we propose an analytical approach based on the modified differential transform method to investigate the dynamic behavior of a plucking energy harvester. The harvester consists of a piezoelectric cantilever oscillator and a rotating plectrum. The analytical approach provides a closed-form solution that helps determine the starting and ending points of the contact phase between the piezoelectric cantilever and the plectrum. This analytical approach is valuable for simulating complex dynamic interferences in multiple or periodic plucking processes. To evaluate the effects of plucking speed and overlap length of the plectrum on single and periodic plucking, a series of simulations were carried out. The output voltage of the piezoelectric energy harvester increases as the overlap length of the plectrum increases. On the other hand, increasing the plucking speed tends to amplify the magnitude of the contact force while reducing the duration of the contact phase. Therefore, it is crucial to optimize the plucking speed to achieve the maximum linear impulse. For periodic plucking, successful synchronization between the motions of the piezoelectric energy harvester and the rotating plectrum must occur within a limited contact zone. Otherwise, dynamic interferences often cause the plectrum to fail to pluck the energy harvester exactly within the contact zone. Additionally, reducing the plucking speed of the plectrum and increasing the overlap length would be more advantageous for successful periodic-plucking energy harvesting.

Load Resistance Optimization of Bi-Stable Electromagnetic Energy Harvester Based on Harmonic Balance.

In this study, a semi-analytic approach to optimizing the external load resistance of a bi-stable electromagnetic energy harvester is presented based on the harmonic balance method. The harmonic balance analyses for the primary harmonic (period-1T) and two subharmonic (period-3T and 5T) interwell motions of the energy harvester are performed with the Fourier series solutions of the individual motions determined by spectral analyses. For each motion, an optimization problem for maximizing the output power of the energy harvester is formulated based on the harmonic balance solutions and then solved to estimate the optimal external load resistance. The results of a parametric study show that the optimal load resistance significantly depends on the inductive reactance and internal resistance of a solenoid coil--the higher the oscillation frequency of an interwell motion (or the larger the inductance of the coil) is, the larger the optimal load resistance. In particular, when the frequency of the ambient vibration source is relatively high, the non-linear dynamic characteristics of an interwell motion should be considered in the optimization process of the electromagnetic energy harvester. Compared with conventional resistance-matching techniques, the proposed semi-analytic approach could provide a more accurate estimation of the external load resistance.

Ellagic Acid Prevents Particulate Matter-Induced Pulmonary Inflammation and Hyperactivity in Mice: A Pilot Study.

The inhalation of fine particulate matter (PM) is a significant health-related environmental issue. Previously, we demonstrated that repeated PM exposure causes hyperlocomotive activity in mice, as well as inflammatory and hypoxic responses in their lungs. In this study, we evaluated the potential efficacy of ellagic acid (EA), a natural polyphenolic compound, against PM-induced pulmonary and behavioral abnormalities in mice. Four treatment groups were assigned in this study (n = 8): control (CON), particulate-matter-instilled (PMI), low-dose EA with PMI (EL + PMI), and high-dose EA with PMI (EH + PMI). EA (20 and 100 mg/kg body weight for low dose and high dose, respectively) was orally administered for 14 days in C57BL/6 mice, and after the eighth day, PM (5 mg/kg) was intratracheally instilled for 7 consecutive days. PM exposure induced inflammatory cell infiltration in the lungs following EA pretreatment. Moreover, PM exposure induced inflammatory protein expression in the bronchoalveolar lavage fluid and the expression of inflammatory (tumor necrosis factor alpha (Tnfα), interleukin (Il)-1b, and Il-6) and hypoxic (vascular endothelial growth factor alpha (Vegfα), ankyrin repeat domain 37 (Ankrd37)) response genes. However, EA pretreatment markedly prevented the induction of expression of inflammatory and hypoxic response genes in the lungs. Furthermore, PM exposure significantly triggered hyperactivity by increasing the total moving distance with an increase in moving speed in the open field test. On the contrary, EA pretreatment significantly prevented PM-induced hyperactivity. In conclusion, dietary intervention with EA may be a potential strategy to prevent PM-induced pathology and activity.

Dietary Intervention with Quercetin Attenuates Diesel Exhaust Particle-Instilled Pulmonary Inflammation and Behavioral Abnormalities in Mice.

Exposure to diesel exhaust particles (DEPs) is inevitable and closely linked with increased health hazards, causing pulmonary abnormalities by increasing inflammation, hypoxia, and so on. Moreover, long-term exposure to DEPs may trigger whole-body toxicity with behavioral alterations. Therefore, nutritional intervention with natural components may be desirable to prevent and/or ameliorate DEP-inducible pathophysiology in mammals. Quercetin has been demonstrated to reduce metabolic complications by possessing antioxidative, anti-inflammatory, and antimutagenic effects. In this study, we investigated the effects of quercetin on pulmonary inflammation and behavioral alteration in male C57BL/6 mice against DEP instillation. The experimental mice were separated into four treatment groups (n = 8 per group), which include: vehicle control, DEP instillation, dietary intervention with a low dose of quercetin (20 mg/kg) for 14 days with DEP instillation for 7 days, or dietary intervention with a high dose of quercetin (100 mg/kg) for 14 days with DEP instillation for 7 days. Compared with the DEP-instilled group, dietary intervention with quercetin significantly attenuated eosinophils in the bronchoalveolar lavage fluid analysis, pulmonary cytokine, and hypoxic mRNA expressions regardless of quercetin concentrations. DEP instillation triggered hyperactivities in the experimental mice, while quercetin pretreatment successfully normalized DEP-inducible abnormalities regardless of the dosage. Therefore, dietary intervention with quercetin may be an applicable means to prevent DEP-triggered pulmonary and behavioral abnormalities.

An Exploratory Study of the Relationships Between Diesel Engine Exhaust Particle Inhalation, Pulmonary Inflammation and Anxious Behavior.

Recent technical developments brought negative side effects such as air pollution and large-scale fires, increasingly exposing people to diesel engine exhaust particles (DEP). Testing how DEP inhalation triggers pathophysiology in animal models could be useful in determining how it affects humans. To this end, the aim of this study was to investigate the effects of pulmonary exposure to DEP for seven consecutive days in experimental male C5BL6/N mice. Twenty-four C5BL6/N mice were treated with one of the three test materials: distilled water for control, a low DEP exposure (5 mg/kg), or a high DEP exposure (15 mg/kg). Exposure to DEP induced decreased body weight; however, it gradually increased pulmonary weight in a DEP-dose-dependent manner. DEP exposure significantly elevated soot accumulation in the lungs, with the alteration of pulmonary homeostasis. It also elevated infiltrated immune cells, thus significantly increasing inflammatory cytokine mRNA and protein production in the lungs and broncho-alveolar lavage fluid, respectively. Pulmonary DEP exposure also altered behavioral responses in the open field test (OFT). Low exposure elevated moving distance and speed, while significantly decreasing the number of trials to enter the central zone. Different concentrations of DEP resulted in different behavioral changes; however, while anxiety levels increased, their degree was independent of DEP concentrations. Results suggest that DEP exposure may possess pro-inflammatory responses in the lungs and trigger anxiety.