Detalles de la búsqueda
1.
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy.
Med Res Rev;
38(4): 1031-1072, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28682469
2.
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Bioorg Chem;
80: 361-374, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29986184
3.
Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.
J Enzyme Inhib Med Chem;
33(1): 727-742, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29620429
4.
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists.
Med Res Rev;
37(4): 936-983, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27976413
5.
Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor.
Bioorg Med Chem;
22(1): 148-66, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24332652
6.
Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.
Bioorg Med Chem;
20(2): 1046-59, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22204739
7.
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Bioorg Med Chem;
20(5): 1690-8, 2012 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22325155
8.
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.
J Med Chem;
62(3): 1274-1290, 2019 02 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30633509
9.
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.
Bioorg Med Chem;
16(5): 2419-30, 2008 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18077171
10.
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists.
Bioorg Med Chem;
16(24): 10281-94, 2008 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19006671
11.
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.
J Med Chem;
61(3): 1340-1354, 2018 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29309142
12.
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Eur J Med Chem;
143: 683-698, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29220790
13.
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents.
Eur J Med Chem;
134: 258-270, 2017 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28419928
14.
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.
Sci Rep;
7: 46356, 2017 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28406191
15.
Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB2 cannabinoid receptor inverse agonists.
Eur J Med Chem;
113: 11-27, 2016 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26922225
16.
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole.
Sci Rep;
6: 26602, 2016 05 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-27216165
17.
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists.
J Med Chem;
58(13): 5355-60, 2015 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-26046697
18.
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH).
Eur J Med Chem;
97: 289-305, 2015 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26002335
19.
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor.
J Med Chem;
58(7): 3253-67, 2015 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25780876
20.
Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors.
Med Chem;
11(4): 342-53, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25494808