Detalles de la búsqueda
1.
Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: Design, synthesis, bioactivity evaluation, and in silico studies.
Bioorg Chem;
133: 106383, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36764231
2.
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases.
Molecules;
27(19)2022 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36234686
3.
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase.
Bioorg Med Chem;
31: 115962, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33422908
4.
Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases.
Molecules;
26(21)2021 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34770981
5.
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor.
Molecules;
26(15)2021 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34361750
6.
Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest.
Bioorg Chem;
94: 103347, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31810757
7.
Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation.
J Enzyme Inhib Med Chem;
35(1): 1840-1853, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33040634
8.
From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3).
Org Biomol Chem;
18(1): 154-162, 2019 12 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31803883
9.
Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies.
Bioorg Med Chem;
27(10): 2083-2089, 2019 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30967303
10.
Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi.
Mar Drugs;
17(10)2019 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31600933
11.
Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides.
Mar Drugs;
17(2)2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30717235
12.
Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration.
Bioorg Med Chem Lett;
28(13): 2250-2255, 2018 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29853332
13.
From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines.
Molecules;
23(11)2018 Nov 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30428591
14.
Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129.
Mar Drugs;
15(4)2017 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28387732
15.
[Screening marine resources to find novel chemical inhibitors of disease-relevant protein kinases]. / Le criblage à Roscoff - Une recherche d'inhibiteurs de kinases tournée vers la mer.
Med Sci (Paris);
31(5): 538-45, 2015 May.
Artículo
en Francés
| MEDLINE | ID: mdl-26059305
16.
Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases.
Molecules;
20(7): 12412-35, 2015 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26184130
17.
Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration.
ACS Pharmacol Transl Sci;
7(5): 1377-1385, 2024 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38751642
18.
Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity.
Eur J Med Chem;
236: 114369, 2022 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35447555
19.
Synthesis and biological evaluation of selected 7H-pyrrolo[2,3-d]pyrimidine derivatives as novel CDK9/CyclinT and Haspin inhibitors.
Chem Biol Interact;
349: 109643, 2021 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34508710
20.
Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors.
Chem Biol Interact;
343: 109478, 2021 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33905741