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1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
J Pharmacol Exp Ther;
323(3): 822-30, 2007 Dec.
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| MEDLINE | ID: mdl-17895400
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