Combined fungal and bacterial infection in deep burns of the lower limb - a case report.

Fungal infections are one of the most common diseases. Superficial mycoses affect the skin and visible mucous membranes. Deep mycoses include organ and systemic mycoses. The incidence of these diseases is increasing due to the use of broad-spectrum antibiotics, corticosteroids and cytostatics. Mycoses (yeasts and filamentous fungi) occur more often in patients with burns than in other patients; especially in patients with large and deep extent burns. In this case report, we are presenting a case of a 62-year-old patient hospitalized at the Department of Burns and Plastic Surgery, University Hospital Brno, with extensive deep burns (2nd-4th degree) covering 35% total body surface area (TBSA), predominantly in both lower limbs. During hospitalization, the patient was diagnosed with a combined bacterial and fungal infection for which targeted therapy was indicated.

Rare Mucor circinelloides and Fusarium infection in latissimus free flap reconstruction after devastating foot injury in non-neutropenic patient.

Nowadays, free flap reconstruction in devastating lower limb trauma is a standard procedure in reconstructive surgery. The greatest factor directly affecting limb salvage is still the risk of infectious complications, whether local or systemic. Fungal wound infections are not among the most common infection complications in surgery, but their low incidence is compensated for by their fulminant and serious course, as well as severe local tissue destruction and strong angio-invasive potential together with the possibility of dissemination. In this case study, we present an example of a devastating lower leg injury, solved using latissimus free flap reconstruction, with subsequent difficult and prolonged healing, due to an invasive filamentous fungi infection. In the final part of the article, we focus briefly on the occurrence of similar cases in the literature.