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1.

Safety, pharmacokinetics and pharmacodynamics of TAK-418, a novel inhibitor of the epigenetic modulator lysine-specific demethylase 1A.

Yin, Wei; Arkilo, Dimitrios; Khudyakov, Polyna; Hazel, Jim; Gupta, Saurabh; Quinton, Maria S; Lin, Jie; Hartman, Deborah S; Bednar, Martin M; Rosen, Laura; Wendland, Jens R.

Br J Clin Pharmacol; 87(12): 4756-4768, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-33990969

2.

Current state of Alzheimer's fluid biomarkers.

Molinuevo, José Luis; Ayton, Scott; Batrla, Richard; Bednar, Martin M; Bittner, Tobias; Cummings, Jeffrey; Fagan, Anne M; Hampel, Harald; Mielke, Michelle M; Mikulskis, Alvydas; O'Bryant, Sid; Scheltens, Philip; Sevigny, Jeffrey; Shaw, Leslie M; Soares, Holly D; Tong, Gary; Trojanowski, John Q; Zetterberg, Henrik; Blennow, Kaj.

Acta Neuropathol; 136(6): 821-853, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30488277

3.

Phosphodiesterase-5 Inhibitor PF-03049423 Effect on Stroke Recovery: A Double-Blind, Placebo-Controlled Randomized Clinical Trial.

Di Cesare, Franco; Mancuso, Jessica; Woodward, Phil; Bednar, Martin M; Loudon, Peter T.

J Stroke Cerebrovasc Dis; 25(3): 642-9, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-26738812

4.

Safety and pharmacokinetics of PF-04360365 following a single-dose intravenous infusion in Japanese subjects with mild-to-moderate Alzheimer's disease: a multicenter, randomized, double-blind, placebo-controlled, dose-escalation study.

Miyoshi, Izuru; Fujimoto, Yoko; Yamada, Masahito; Abe, Sadahiro; Zhao, Qinying; Cronenberger, Carol; Togo, Kanae; Ishibashi, Taro; Bednar, Martin M; Kupiec, James W; Binneman, Brendon.

Int J Clin Pharmacol Ther; 51(12): 911-23, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-24131736

5.

The histamine skin prick test: An analysis of the method for use in clinical trials.

Brevard, Julie; Elder, Mary Anne; Berman, Gary; Tan, Ye; Volfson, Dmitri; Ogden, Adam; Evans, Barbara; Bednar, Martin M.

Ann Allergy Asthma Immunol; 117(4): 433-435, 2016 10.

Artículo en Inglés | MEDLINE | ID: mdl-27519579

6.

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup.

Sperling, Reisa A; Jack, Clifford R; Black, Sandra E; Frosch, Matthew P; Greenberg, Steven M; Hyman, Bradley T; Scheltens, Philip; Carrillo, Maria C; Thies, William; Bednar, Martin M; Black, Ronald S; Brashear, H Robert; Grundman, Michael; Siemers, Eric R; Feldman, Howard H; Schindler, Rachel J.

Alzheimers Dement; 7(4): 367-85, 2011 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-21784348

7.

Endogenous tissue generation and restoration: Maximizing our human potential.

Bednar, Martin M.

Issues Law Med; 31(2): 217-220, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-29108181

8.

Stroke: working toward a prioritized world agenda.

Hachinski, Vladimir; Donnan, Geoffrey A; Gorelick, Philip B; Hacke, Werner; Cramer, Steven C; Kaste, Markku; Fisher, Marc; Brainin, Michael; Buchan, Alastair M; Lo, Eng H; Skolnick, Brett E; Furie, Karen L; Hankey, Graeme J; Kivipelto, Miia; Morris, John; Rothwell, Peter M; Sacco, Ralph L; Smith, Sidney C; Wang, Yulun; Bryer, Alan; Ford, Gary A; Iadecola, Costantino; Martins, Sheila C O; Saver, Jeff; Skvortsova, Veronika; Bayley, Mark; Bednar, Martin M; Duncan, Pamela; Enney, Lori; Finklestein, Seth; Jones, Theresa A; Kalra, Lalit; Kleim, Jeff; Nitkin, Ralph; Teasell, Robert; Weiller, Cornelius; Desai, Bhupat; Goldberg, Mark P; Heiss, Wolf-Dieter; Saarelma, Osmo; Schwamm, Lee H; Shinohara, Yukito; Trivedi, Bhargava; Wahlgren, Nils; Wong, Lawrence K; Hakim, Antoine; Norrving, Bo; Prudhomme, Stephen; Bornstein, Natan M; Davis, Stephen M.

Stroke; 41(6): 1084-99, 2010 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-20498453

9.

Stroke: working toward a prioritized world agenda.

Hachinski, Vladimir; Donnan, Geoffrey A; Gorelick, Philip B; Hacke, Werner; Cramer, Steven C; Kaste, Markku; Fisher, Marc; Brainin, Michael; Buchan, Alastair M; Lo, Eng H; Skolnick, Brett E; Furie, Karen L; Hankey, Graeme J; Kivipelto, Miia; Morris, John; Rothwell, Peter M; Sacco, Ralph L; Smith, Sidney C; Wang, Yulun; Bryer, Alan; Ford, Gary A; Iadecola, Costantino; Martins, Sheila C O; Saver, Jeff; Skvortsova, Veronika; Bayley, Mark; Bednar, Martin M; Duncan, Pamela; Enney, Lori; Finklestein, Seth; Jones, Theresa A; Kalra, Lalit; Kleim, Jeff; Nitkin, Ralph; Teasell, Robert; Weiller, Cornelius; Desai, Bhupat; Goldberg, Mark P; Heiss, Wolf-Dieter; Saarelma, Osmo; Schwamm, Lee H; Shinohara, Yukito; Trivedi, Bhargava; Wahlgren, Nils; Wong, Lawrence K; Hakim, Antoine; Norrving, Bo; Prudhomme, Stephen; Bornstein, Natan M; Davis, Stephen M.

Cerebrovasc Dis; 30(2): 127-47, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-20516682

10.

The pathway to secondary prevention of Alzheimer's disease.

McDade, Eric; Bednar, Martin M; Brashear, H Robert; Miller, David S; Maruff, Paul; Randolph, Christopher; Ismail, Zahinoor; Carrillo, Maria C; Weber, Christopher J; Bain, Lisa J; Hake, Ann Marie.

Alzheimers Dement (N Y); 6(1): e12069, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32885024

11.

Combination therapy for Alzheimer's disease and related dementias.

Bednar, Martin M.

Prog Mol Biol Transl Sci; 168: 289-296, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31699322

12.

Immunotherapy with ponezumab for probable cerebral amyloid angiopathy.

Leurent, Claire; Goodman, James A; Zhang, Yao; He, Ping; Polimeni, Jonathan R; Gurol, Mahmut Edip; Lindsay, Monica; Frattura, Linda; Sohur, Usharbudh Shivraj; Viswanathan, Anand; Bednar, Martin M; Smith, Eric E; Greenberg, Steven M.

Ann Clin Transl Neurol; 6(4): 795-806, 2019 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-31020004

13.

The role of sildenafil in the treatment of stroke.

Bednar, Martin M.

Curr Opin Investig Drugs; 9(7): 754-9, 2008 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-18600581

14.

Ponezumab in mild-to-moderate Alzheimer's disease: Randomized phase II PET-PIB study.

Landen, Jaren W; Andreasen, Niels; Cronenberger, Carol L; Schwartz, Pamela F; Börjesson-Hanson, Anne; Östlund, Henrik; Sattler, Catherine A; Binneman, Brendon; Bednar, Martin M.

Alzheimers Dement (N Y); 3(3): 393-401, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-29067345

15.

Multiple-dose ponezumab for mild-to-moderate Alzheimer's disease: Safety and efficacy.

Landen, Jaren W; Cohen, Sharon; Billing, Clare B; Cronenberger, Carol; Styren, Scot; Burstein, Aaron H; Sattler, Catherine; Lee, Jae-Hong; Jack, Clifford R; Kantarci, Kejal; Schwartz, Pamela F; Duggan, William T; Zhao, Qinying; Sprenger, Ken; Bednar, Martin M; Binneman, Brendon.

Alzheimers Dement (N Y); 3(3): 339-347, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-29067341

16.

Interventions for heart disease and their effects on Alzheimer's disease.

Wolozin, Benjamin; Bednar, Martin M.

Neurol Res; 28(6): 630-6, 2006 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-16945215

17.

Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty.

Lee, Todd A; Wolozin, Benjamin; Weiss, Kevin B; Bednar, Martin M.

J Alzheimers Dis; 7(4): 319-24, 2005 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16131734

18.

Reversal of scopolamine-induced deficits with a single dose of donepezil, an acetylcholinesterase inhibitor.

Snyder, Peter J; Bednar, Martin M; Cromer, Jennifer R; Maruff, Paul.

Alzheimers Dement; 1(2): 126-35, 2005 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-19595845

19.

The Safety and Efficacy of PF-04958242 in Age-Related Sensorineural Hearing Loss: A Randomized Clinical Trial.

Bednar, Martin M; DeMartinis, Nick; Banerjee, Anindita; Bowditch, Stephen; Gaudreault, Francois; Zumpano, Laura; Lin, Frank R.

JAMA Otolaryngol Head Neck Surg; 141(7): 607-13, 2015 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-25997115

20.

Combining antiplatelet and thrombolytic therapies for stroke.

Bednar, Martin M.

Expert Opin Pharmacother; 3(4): 401-10, 2002 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-11934343

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Safety, pharmacokinetics and pharmacodynamics of TAK-418, a novel inhibitor of the epigenetic modulator lysine-specific demethylase 1A.

Current state of Alzheimer's fluid biomarkers.

Phosphodiesterase-5 Inhibitor PF-03049423 Effect on Stroke Recovery: A Double-Blind, Placebo-Controlled Randomized Clinical Trial.

Safety and pharmacokinetics of PF-04360365 following a single-dose intravenous infusion in Japanese subjects with mild-to-moderate Alzheimer's disease: a multicenter, randomized, double-blind, placebo-controlled, dose-escalation study.

The histamine skin prick test: An analysis of the method for use in clinical trials.

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup.

Endogenous tissue generation and restoration: Maximizing our human potential.

Stroke: working toward a prioritized world agenda.

Stroke: working toward a prioritized world agenda.

The pathway to secondary prevention of Alzheimer's disease.

Combination therapy for Alzheimer's disease and related dementias.

Immunotherapy with ponezumab for probable cerebral amyloid angiopathy.

The role of sildenafil in the treatment of stroke.

Ponezumab in mild-to-moderate Alzheimer's disease: Randomized phase II PET-PIB study.

Multiple-dose ponezumab for mild-to-moderate Alzheimer's disease: Safety and efficacy.

Interventions for heart disease and their effects on Alzheimer's disease.

Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty.

Reversal of scopolamine-induced deficits with a single dose of donepezil, an acetylcholinesterase inhibitor.

The Safety and Efficacy of PF-04958242 in Age-Related Sensorineural Hearing Loss: A Randomized Clinical Trial.

Combining antiplatelet and thrombolytic therapies for stroke.