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1.
Synthesis and evaluation of pyridylbenzofuran, pyridylbenzothiazole and pyridylbenzoxazole derivatives as ¹8F-PET imaging agents for ß-amyloid plaques.
Bioorg Med Chem Lett;
22(13): 4332-7, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22647721
2.
Synthesis and evaluation of 2-pyridylbenzothiazole, 2-pyridylbenzoxazole and 2-pyridylbenzofuran derivatives as 11C-PET imaging agents for beta-amyloid plaques.
Bioorg Med Chem Lett;
20(6): 1976-80, 2010 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20153963
3.
In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Abeta aggregation.
Bioorg Med Chem;
18(16): 5896-902, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20659803
4.
Optimizing DMPK Properties: Experiences from a Big Pharma DMPK Department.
Curr Drug Metab;
17(3): 253-70, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26651977
5.
Core refinement toward permeable ß-secretase (BACE-1) inhibitors with low hERG activity.
J Med Chem;
56(11): 4181-205, 2013 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23126626
6.
Discovery of novel potent and highly selective glycogen synthase kinase-3ß (GSK3ß) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J Med Chem;
55(21): 9107-19, 2012 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22489897
7.
Design and synthesis of ß-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of ß-amyloid peptides.
J Med Chem;
55(21): 9346-61, 2012 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22924815
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